SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d86'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 PRO A 235
PHE A 152
THR A  74
SER A 189
MET A 191
 None
None
None
PLP  A1001 (-2.7A)
None
 1.34A 1fm4A-5d86A:
undetectable		 1fm4A-5d86A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		4 / 6 LEU A 297
LEU A  37
PRO A  20
MET A  21
 None
 1.28A 1hz4A-5d86A:
undetectable		 1hz4A-5d86A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		4 / 6 ASP A 250
GLY A 257
ILE A 277
ILE A 229
 None
 0.77A 1n49D-5d86A:
undetectable		 1n49D-5d86A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 GLY A 271
ALA A 255
GLY A 257
ALA A 278
LEU A 307
 None
 1.03A 2nyuA-5d86A:
undetectable		 2nyuA-5d86A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 9 ASP A 250
GLY A 274
ILE A 277
VAL A 207
ILE A 247
 None
 1.06A 2q5kA-5d86A:
undetectable		 2q5kA-5d86A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 9 ILE A 229
GLY A 274
ILE A 277
VAL A 207
ILE A 247
 None
 1.18A 2r5qA-5d86A:
undetectable		 2r5qA-5d86A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 9 ILE A 229
GLY A 274
ILE A 277
VAL A 207
ILE A 247
 None
 1.18A 2r5qC-5d86A:
undetectable		 2r5qC-5d86A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 LEU A  24
ILE A 277
GLU A 265
LEU A 261
ASP A 263
 None
 1.16A 3ko0A-5d86A:
undetectable
3ko0B-5d86A:
undetectable
3ko0C-5d86A:
undetectable
3ko0D-5d86A:
undetectable		 3ko0A-5d86A:
16.92
3ko0B-5d86A:
16.92
3ko0C-5d86A:
16.92
3ko0D-5d86A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 GLU A 265
LEU A 261
ASP A 263
LEU A  24
ILE A 277
 None
 1.16A 3ko0K-5d86A:
undetectable
3ko0L-5d86A:
undetectable
3ko0M-5d86A:
undetectable
3ko0N-5d86A:
undetectable		 3ko0K-5d86A:
16.92
3ko0L-5d86A:
16.92
3ko0M-5d86A:
16.92
3ko0N-5d86A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 LEU A  24
ILE A 277
GLU A 265
LEU A 261
ASP A 263
 None
 1.15A 3ko0M-5d86A:
undetectable
3ko0N-5d86A:
undetectable
3ko0O-5d86A:
undetectable
3ko0P-5d86A:
undetectable		 3ko0M-5d86A:
16.92
3ko0N-5d86A:
16.92
3ko0O-5d86A:
16.92
3ko0P-5d86A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 GLU A 265
LEU A 261
ASP A 263
LEU A  24
ILE A 277
 None
 1.13A 3ko0M-5d86A:
undetectable
3ko0N-5d86A:
undetectable
3ko0O-5d86A:
undetectable
3ko0P-5d86A:
undetectable		 3ko0M-5d86A:
16.92
3ko0N-5d86A:
16.92
3ko0O-5d86A:
16.92
3ko0P-5d86A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		3 / 3 LYS A 100
ARG A 132
LYS A  47
 None
None
PLP  A1001 (-1.3A)
 1.26A 3okxA-5d86A:
undetectable		 3okxA-5d86A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 GLY A 270
SER A 254
GLY A 228
LEU A 261
PHE A 268
 None
None
PLP  A1001 (-4.1A)
None
None
 1.30A 3r24A-5d86A:
undetectable		 3r24A-5d86A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 GLY A 270
SER A 275
GLY A 228
LEU A 261
PHE A 268
 None
None
PLP  A1001 (-4.1A)
None
None
 1.36A 3r24A-5d86A:
undetectable		 3r24A-5d86A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 GLY A 274
GLY A 270
ASP A 250
VAL A 249
GLY A 257
 None
 0.96A 3sglA-5d86A:
undetectable		 3sglA-5d86A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		4 / 6 CYH A  95
THR A  94
ASN A 115
ILE A 101
 None
 1.17A 3w9tB-5d86A:
undetectable		 3w9tB-5d86A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 PRO A 235
PHE A 152
LEU A  78
SER A 189
MET A 191
 None
None
None
PLP  A1001 (-2.7A)
None
 1.44A 4a84A-5d86A:
undetectable		 4a84A-5d86A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		4 / 5 PRO A 298
ASP A 299
ILE A 229
VAL A 308
 PLP  A1001 (-4.3A)
PLP  A1001 (-3.2A)
None
None
 0.97A 4hytA-5d86A:
3.6		 4hytA-5d86A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 10 ASP A 299
VAL A 308
TYR A 304
SER A 272
GLY A 274
 PLP  A1001 (-3.2A)
None
None
PLP  A1001 (-2.6A)
None
 1.38A 4xp1A-5d86A:
undetectable		 4xp1A-5d86A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 11 ILE A 101
THR A  74
SER A  75
GLY A  76
ARG A 303
 None
 1.35A 4xt7A-5d86A:
2.2		 4xt7A-5d86A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		4 / 8 ILE A  55
LEU A  91
ILE A  85
LEU A  13
 None
 0.82A 4zvcA-5d86A:
undetectable
4zvcB-5d86A:
undetectable		 4zvcA-5d86A:
17.03
4zvcB-5d86A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		4 / 8 ILE A  85
LEU A  13
ILE A  55
LEU A  91
 None
 0.81A 4zvcA-5d86A:
undetectable
4zvcB-5d86A:
undetectable		 4zvcA-5d86A:
17.03
4zvcB-5d86A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		5 / 12 GLY A  43
GLY A  76
GLY A  79
THR A  74
ASP A  98
 None
 1.00A 5njvD-5d86A:
undetectable		 5njvD-5d86A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA
(Staphylococcus
aureus) 		6 / 12 ILE A  80
ALA A  81
ALA A  83
LEU A  93
ALA A  51
ILE A 101
 None
 1.48A 6a60D-5d86A:
undetectable		 6a60D-5d86A:
11.64