SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		5 / 12 VAL A  60
ILE A  24
ILE A  49
VAL A  95
LEU A  93
 None
 1.07A 1qhyA-5d88A:
undetectable		 1qhyA-5d88A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		5 / 11 VAL A 179
ARG A 209
LEU A  36
ILE A 173
ASP A 177
 None
None
ACT  A 302 (-3.9A)
ACT  A 302 (-3.8A)
None
 1.36A 1t6zA-5d88A:
undetectable		 1t6zA-5d88A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		5 / 11 VAL A 179
ARG A 209
LEU A  36
ILE A 173
ASP A 177
 None
None
ACT  A 302 (-3.9A)
ACT  A 302 (-3.8A)
None
 1.28A 1t6zB-5d88A:
undetectable		 1t6zB-5d88A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		5 / 11 GLY A  70
ALA A  69
ASP A 102
GLY A  78
THR A  85
 ZN  A 301 ( 4.3A)
None
None
None
None
 0.93A 3ekxA-5d88A:
undetectable		 3ekxA-5d88A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		3 / 3 TYR A  40
ASP A  65
ASP A 102
 None
 0.91A 3ou6B-5d88A:
undetectable		 3ou6B-5d88A:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		4 / 7 ASP A  15
THR A  16
SER A  10
HIS A  12
 None
 1.41A 4o4dA-5d88A:
undetectable		 4o4dA-5d88A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		4 / 5 SER A 120
ALA A 101
HIS A 121
LEU A  63
 None
None
ACT  A 302 (-3.9A)
None
 1.40A 5dzkf-5d88A:
2.4
5dzkt-5d88A:
undetectable		 5dzkf-5d88A:
22.18
5dzkt-5d88A:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		4 / 5 HIS A 133
VAL A 119
GLY A 138
ALA A 139
 None
 0.98A 5hwaA-5d88A:
undetectable		 5hwaA-5d88A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		4 / 6 GLU A  45
ARG A  39
VAL A  26
PRO A  27
 None
 1.41A 6fgdA-5d88A:
undetectable		 6fgdA-5d88A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		5 / 12 LEU A   7
LEU A  37
ILE A 173
HIS A 121
ASP A  65
 None
None
ACT  A 302 (-3.8A)
ACT  A 302 (-3.9A)
None
 1.33A 6n91A-5d88A:
4.2		 6n91A-5d88A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		5 / 12 LEU A   7
LEU A  37
ILE A 173
HIS A 121
ASP A  65
 None
None
ACT  A 302 (-3.8A)
ACT  A 302 (-3.9A)
None
 1.29A 6n91B-5d88A:
3.5		 6n91B-5d88A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY
(Methanopyrus
kandleri) 		3 / 3 THR A 168
GLU A 154
ASN A 149
 None
 0.78A 6nj9K-5d88A:
undetectable		 6nj9K-5d88A:
21.38