SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d8i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 3jx5A-5d8iA:
undetectable
3jx5B-5d8iA:
undetectable		 3jx5A-5d8iA:
23.33
3jx5B-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.16A 3n5vA-5d8iA:
undetectable
3n5vB-5d8iA:
undetectable		 3n5vA-5d8iA:
23.33
3n5vB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.24A 3n5vA-5d8iA:
undetectable
3n5vB-5d8iA:
undetectable		 3n5vA-5d8iA:
23.33
3n5vB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.25A 3n5yA-5d8iA:
undetectable
3n5yB-5d8iA:
undetectable		 3n5yA-5d8iA:
23.33
3n5yB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.25A 3n5zA-5d8iA:
undetectable
3n5zB-5d8iA:
undetectable		 3n5zA-5d8iA:
23.33
3n5zB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 3n5zA-5d8iA:
undetectable
3n5zB-5d8iA:
undetectable		 3n5zA-5d8iA:
23.33
3n5zB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.28A 3svpA-5d8iA:
undetectable
3svpB-5d8iA:
undetectable		 3svpA-5d8iA:
23.33
3svpB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.28A 3ufoA-5d8iA:
undetectable
3ufoB-5d8iA:
undetectable		 3ufoA-5d8iA:
23.33
3ufoB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.31A 3ufsA-5d8iA:
undetectable
3ufsB-5d8iA:
undetectable		 3ufsA-5d8iA:
23.33
3ufsB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.26A 4imwA-5d8iA:
undetectable
4imwB-5d8iA:
undetectable		 4imwA-5d8iA:
23.33
4imwB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.33A 4imwA-5d8iA:
undetectable
4imwB-5d8iA:
undetectable		 4imwA-5d8iA:
23.33
4imwB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.23A 4jsfA-5d8iA:
undetectable
4jsfB-5d8iA:
undetectable		 4jsfA-5d8iA:
23.33
4jsfB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.27A 4jsiA-5d8iA:
undetectable
4jsiB-5d8iA:
undetectable		 4jsiA-5d8iA:
23.33
4jsiB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.21A 5ad4A-5d8iA:
undetectable
5ad4B-5d8iA:
undetectable		 5ad4A-5d8iA:
23.33
5ad4B-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 5ad4A-5d8iA:
undetectable
5ad4B-5d8iA:
undetectable		 5ad4A-5d8iA:
23.33
5ad4B-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 5fvuA-5d8iA:
undetectable
5fvuB-5d8iA:
undetectable		 5fvuA-5d8iA:
22.93
5fvuB-5d8iA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 10 PHE A 195
ARG A 220
PRO A 173
ALA A 174
VAL A 229
 None
 1.11A 5m0oA-5d8iA:
undetectable		 5m0oA-5d8iA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 8 PHE A 195
ARG A 220
PRO A 173
ALA A 174
 None
 0.94A 5m0oC-5d8iA:
undetectable		 5m0oC-5d8iA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.18A 5unvA-5d8iA:
undetectable
5unvB-5d8iA:
undetectable		 5unvA-5d8iA:
23.33
5unvB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 6 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.23A 5unvA-5d8iA:
undetectable
5unvB-5d8iA:
undetectable		 5unvA-5d8iA:
23.33
5unvB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.19A 5vujA-5d8iA:
undetectable
5vujB-5d8iA:
undetectable		 5vujA-5d8iA:
23.33
5vujB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.24A 5vujA-5d8iA:
undetectable
5vujB-5d8iA:
undetectable		 5vujA-5d8iA:
23.33
5vujB-5d8iA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 5 ASN A 246
VAL A 216
LEU A 266
SER A 250
 None
 1.10A 6a7pA-5d8iA:
undetectable		 6a7pA-5d8iA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d8i SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.26A 6auqA-5d8iA:
undetectable
6auqB-5d8iA:
undetectable		 6auqA-5d8iA:
14.58
6auqB-5d8iA:
14.58