SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d8w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 7 ASP A 215
TRP A 264
PHE A 232
ARG A 270
None
1.42A 1b2iA-5d8wA:
undetectable
1b2iA-5d8wA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 5 GLU A 322
ARG A  76
ASP A 118
THR A 203
None
1.46A 1k4tA-5d8wA:
undetectable
1k4tA-5d8wA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RR8_A_TTCA100_1
(DNA TOPOISOMERASE I)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 5 GLU A 322
ARG A  76
ASP A 118
THR A 203
None
1.40A 1rr8C-5d8wA:
undetectable
1rr8C-5d8wA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RRJ_B_TTCB990_1
(DNA TOPOISOMERASE I)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 5 GLU A 322
ARG A  76
ASP A 118
THR A 203
None
1.40A 1rrjA-5d8wA:
undetectable
1rrjA-5d8wA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 12 LEU A 104
LEU A  51
GLY A 312
ASN A 313
ALA A  30
None
1.10A 2bm9C-5d8wA:
undetectable
2bm9C-5d8wA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 10 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.93A 2f16K-5d8wA:
undetectable
2f16L-5d8wA:
undetectable
2f16K-5d8wA:
20.82
2f16L-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 10 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.92A 2f16Y-5d8wA:
undetectable
2f16Z-5d8wA:
undetectable
2f16Y-5d8wA:
20.82
2f16Z-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 7 ASP A 215
TRP A 264
PHE A 232
ARG A 270
None
1.20A 2pk4A-5d8wA:
undetectable
2pk4A-5d8wA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
6 / 12 ASN A 163
GLU A 164
HIS A 235
TYR A 237
GLU A 276
TRP A 309
None
0.80A 2v3dA-5d8wA:
7.3
2v3dA-5d8wA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 11 ASN A 163
GLU A 164
TYR A 237
GLU A 276
TRP A 309
None
0.89A 2v3dB-5d8wA:
6.4
2v3dB-5d8wA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 7 ASP A 215
TRP A 264
PHE A 232
ARG A 270
None
1.21A 3kivA-5d8wA:
undetectable
3kivA-5d8wA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 7 GLY A  59
PHE A  24
PHE A 273
PHE A  75
None
1.12A 3ko0L-5d8wA:
undetectable
3ko0N-5d8wA:
undetectable
3ko0L-5d8wA:
11.58
3ko0N-5d8wA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 7 PHE A  75
GLY A  59
PHE A  24
PHE A 273
None
1.09A 3ko0K-5d8wA:
undetectable
3ko0S-5d8wA:
undetectable
3ko0K-5d8wA:
11.58
3ko0S-5d8wA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 11 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.93A 3mg0K-5d8wA:
undetectable
3mg0L-5d8wA:
undetectable
3mg0K-5d8wA:
20.82
3mg0L-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 12 PHE A  34
PRO A  50
PRO A  78
VAL A 307
ALA A 311
None
1.40A 4a84A-5d8wA:
undetectable
4a84A-5d8wA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 8 ASP A 233
ASP A 118
ASN A 163
ASP A  33
None
1.14A 4gkhC-5d8wA:
undetectable
4gkhK-5d8wA:
undetectable
4gkhC-5d8wA:
21.29
4gkhK-5d8wA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 8 ASP A 233
ASP A 118
ASN A 163
ASP A  33
None
1.13A 4gkiE-5d8wA:
undetectable
4gkiG-5d8wA:
undetectable
4gkiE-5d8wA:
21.29
4gkiG-5d8wA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 12 TRP A 258
ALA A 272
ASP A 233
ILE A 158
GLY A 308
None
1.42A 4iilA-5d8wA:
undetectable
4iilA-5d8wA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 12 LEU A 173
PRO A 169
ALA A 123
ASP A 139
GLY A 134
None
1.09A 4j7xA-5d8wA:
2.0
4j7xA-5d8wA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 5 LEU A 304
GLY A 305
ILE A 158
LYS A 156
None
1.12A 4ma8C-5d8wA:
undetectable
4ma8C-5d8wA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 11 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.95A 4qvlK-5d8wA:
undetectable
4qvlL-5d8wA:
undetectable
4qvlK-5d8wA:
20.82
4qvlL-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 11 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.95A 4qvlY-5d8wA:
undetectable
4qvlZ-5d8wA:
undetectable
4qvlY-5d8wA:
20.82
4qvlZ-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 9 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.95A 4qvmK-5d8wA:
undetectable
4qvmL-5d8wA:
undetectable
4qvmK-5d8wA:
20.82
4qvmL-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 10 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.95A 4qvmY-5d8wA:
undetectable
4qvmZ-5d8wA:
undetectable
4qvmY-5d8wA:
20.82
4qvmZ-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 9 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.94A 4qvnK-5d8wA:
undetectable
4qvnL-5d8wA:
undetectable
4qvnK-5d8wA:
20.82
4qvnL-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 9 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.95A 4qvnY-5d8wA:
undetectable
4qvnZ-5d8wA:
undetectable
4qvnY-5d8wA:
20.82
4qvnZ-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 10 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.95A 4qvpK-5d8wA:
undetectable
4qvpL-5d8wA:
undetectable
4qvpK-5d8wA:
20.82
4qvpL-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 10 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.95A 4qvpY-5d8wA:
undetectable
4qvpZ-5d8wA:
undetectable
4qvpY-5d8wA:
20.82
4qvpZ-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 9 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.95A 4qvqK-5d8wA:
undetectable
4qvqL-5d8wA:
undetectable
4qvqK-5d8wA:
20.82
4qvqL-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 9 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.94A 4qvqY-5d8wA:
undetectable
4qvqZ-5d8wA:
undetectable
4qvqY-5d8wA:
20.82
4qvqZ-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 11 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.95A 4qw1K-5d8wA:
undetectable
4qw1L-5d8wA:
undetectable
4qw1K-5d8wA:
20.06
4qw1L-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 10 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.96A 4qw1Y-5d8wA:
undetectable
4qw1Z-5d8wA:
undetectable
4qw1Y-5d8wA:
20.06
4qw1Z-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 10 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.94A 4qw3K-5d8wA:
undetectable
4qw3L-5d8wA:
undetectable
4qw3K-5d8wA:
21.10
4qw3L-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 10 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.94A 4qw3Y-5d8wA:
undetectable
4qw3Z-5d8wA:
undetectable
4qw3Y-5d8wA:
21.10
4qw3Z-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 12 ALA A  44
GLY A  87
ILE A 147
GLU A 100
TYR A 101
None
1.01A 4r29D-5d8wA:
undetectable
4r29D-5d8wA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 11 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.94A 5bxnK-5d8wA:
undetectable
5bxnL-5d8wA:
undetectable
5bxnK-5d8wA:
20.82
5bxnL-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 11 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.94A 5bxnY-5d8wA:
undetectable
5bxnZ-5d8wA:
undetectable
5bxnY-5d8wA:
20.82
5bxnZ-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 9 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.96A 5d0xK-5d8wA:
undetectable
5d0xL-5d8wA:
undetectable
5d0xK-5d8wA:
20.83
5d0xL-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 9 ALA A 184
THR A 183
ALA A 181
GLY A 189
ALA A 148
None
0.96A 5d0xY-5d8wA:
undetectable
5d0xZ-5d8wA:
undetectable
5d0xY-5d8wA:
20.83
5d0xZ-5d8wA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 12 ILE A 158
GLY A 160
ASP A 118
ARG A  76
ALA A 190
None
1.02A 5h5fA-5d8wA:
undetectable
5h5fA-5d8wA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 8 LEU A 104
ALA A  47
TYR A  54
GLN A  53
None
1.01A 5nu7A-5d8wA:
undetectable
5nu7A-5d8wA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 12 VAL A  79
ASP A  33
LEU A 109
PRO A  49
LEU A  51
None
1.13A 5syfB-5d8wA:
2.1
5syfB-5d8wA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 12 VAL A  79
ASP A  33
LEU A 109
PRO A  49
LEU A  51
None
1.13A 6b0lB-5d8wA:
undetectable
6b0lB-5d8wA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 5 GLU A 164
ASP A 118
HIS A 120
THR A 275
None
1.30A 6b58A-5d8wA:
undetectable
6b58A-5d8wA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
4 / 5 ASN A 163
GLY A 278
HIS A 235
ASP A 233
None
1.27A 6gh9A-5d8wA:
undetectable
6gh9A-5d8wA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)
5d8w ENDOGLUCANASE
(Ganoderma
lucidum)
5 / 12 ILE A 158
LEU A 304
GLY A 305
PHE A  24
ILE A 231
None
1.08A 6qxsB-5d8wA:
undetectable
6qxsB-5d8wA:
22.02