SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d93'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)
5d93 HEAVY CHAIN OF FAB
FRAGMENT FROM A
MOUSE QSOX1-SPECIFIC
ANTIBODY

(Mus
musculus)
4 / 5 ILE C  34
PRO C  53
TYR C  52
TYR C  33
None
0.81A 3d9lA-5d93C:
undetectable
3d9lY-5d93C:
undetectable
3d9lA-5d93C:
18.26
3d9lY-5d93C:
6.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)
5d93 HEAVY CHAIN OF FAB
FRAGMENT FROM A
MOUSE QSOX1-SPECIFIC
ANTIBODY

(Mus
musculus)
4 / 5 VAL C   2
TYR C  27
ARG C  98
TYR C 105
None
0.23A 4m7kH-5d93C:
25.9
4m7kH-5d93C:
87.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
5d93 HEAVY CHAIN OF FAB
FRAGMENT FROM A
MOUSE QSOX1-SPECIFIC
ANTIBODY

(Mus
musculus)
6 / 12 VAL C 186
THR C 137
LEU C 161
VAL C 165
GLY C 164
VAL C 213
None
1.50A 6a94B-5d93C:
undetectable
6a94B-5d93C:
18.82