SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d95'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		3 / 3 PRO A 337
ASP A 341
ASP A 263
 None
 0.74A 1sqfA-5d95A:
undetectable		 1sqfA-5d95A:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 8 ALA A 397
PHE A 398
ALA A 444
LEU A 441
 None
 0.92A 2bxmA-5d95A:
undetectable		 2bxmA-5d95A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_B_CHDB1_0
(FERROCHELATASE)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 10 LEU A 118
PRO A 223
SER A 259
VAL A 273
GLY A 272
 None
 1.31A 2qd2B-5d95A:
2.2		 2qd2B-5d95A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 10 ILE A 411
ALA A 440
LEU A 417
ILE A 413
PHE A 433
 None
 1.22A 2w9sF-5d95A:
undetectable		 2w9sF-5d95A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 8 GLY A 294
ILE A 284
ALA A 134
HIS A 314
 None
 0.94A 2x0pA-5d95A:
undetectable		 2x0pA-5d95A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 9 ALA A 279
VAL A 293
GLY A 294
GLY A 295
ALA A 134
 None
 0.87A 2z0yA-5d95A:
undetectable		 2z0yA-5d95A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 9 ALA A 279
VAL A 293
GLY A 294
GLY A 295
ALA A 134
 None
 0.92A 2z0yB-5d95A:
undetectable		 2z0yB-5d95A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 5 VAL A 196
VAL A 195
PHE A 199
ARG A 139
 None
 1.39A 3bjwH-5d95A:
1.5		 3bjwH-5d95A:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 12 ALA A 438
ILE A 413
PHE A 433
HIS A 377
LEU A 378
 None
 0.97A 3dzuA-5d95A:
undetectable		 3dzuA-5d95A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 11 PRO A 171
PRO A 198
TYR A 248
ILE A 209
ILE A 202
 None
 1.39A 3ganA-5d95A:
undetectable		 3ganA-5d95A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 9 LEU A 118
PRO A 223
SER A 259
VAL A 273
GLY A 272
 None
 1.34A 3hcoA-5d95A:
2.0		 3hcoA-5d95A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 10 LEU A 118
PRO A 223
SER A 259
VAL A 273
GLY A 272
 None
 1.34A 3hcoB-5d95A:
undetectable		 3hcoB-5d95A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		3 / 3 PRO A  46
SER A  41
ASN A  10
 None
 0.91A 3lslG-5d95A:
undetectable		 3lslG-5d95A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 6 LEU A 197
PHE A 150
ILE A 221
THR A 245
 None
 0.82A 3mdrA-5d95A:
undetectable		 3mdrA-5d95A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 12 ALA A 138
LEU A 216
ILE A 221
LEU A 241
THR A 142
 None
 1.13A 4ej1B-5d95A:
undetectable		 4ej1B-5d95A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		3 / 3 GLN A 366
HIS A 379
ARG A 381
 None
 1.12A 4qyqB-5d95A:
undetectable		 4qyqB-5d95A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 8 ILE A  56
GLY A  77
THR A 423
SER A 372
 None
 0.86A 4r20A-5d95A:
undetectable		 4r20A-5d95A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 8 ASP A 341
PHE A 340
VAL A 270
ASP A 263
 None
 1.15A 4xqgA-5d95A:
undetectable		 4xqgA-5d95A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 8 ASP A 341
PHE A 340
VAL A 270
ASP A 263
 None
 1.15A 4xqgB-5d95A:
undetectable		 4xqgB-5d95A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 5 ILE A 209
GLY A 204
ILE A 244
LEU A 208
 None
 0.88A 5dzki-5d95A:
undetectable
5dzkj-5d95A:
undetectable
5dzkx-5d95A:
undetectable		 5dzki-5d95A:
17.71
5dzkj-5d95A:
17.71
5dzkx-5d95A:
1.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 10 GLY A 369
TYR A 370
GLY A 371
SER A 372
LEU A 373
 None
 1.06A 5hwkA-5d95A:
undetectable		 5hwkA-5d95A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 10 GLY A 369
TYR A 370
GLY A 371
SER A 372
LEU A 373
 None
 1.06A 5hwkB-5d95A:
undetectable		 5hwkB-5d95A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 6 ILE A 135
GLY A 295
MET A 300
ILE A 253
 None
 1.00A 5j4nB-5d95A:
undetectable		 5j4nB-5d95A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		5 / 12 SER A 259
LEU A 260
THR A 278
GLY A 266
VAL A 270
 None
 1.06A 5jo9A-5d95A:
undetectable		 5jo9A-5d95A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 6 GLU A 215
ARG A 146
LEU A 216
ARG A 213
 None
 1.21A 5l6eA-5d95A:
undetectable
5l6eB-5d95A:
undetectable		 5l6eA-5d95A:
19.42
5l6eB-5d95A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 5d95 AMINOTRANSFERASE
CLASS-III
(Sphaerobacter
thermophilus) 		4 / 6 SER A 372
GLU A 339
ARG A 342
ASP A  82
 None
 1.25A 5zw4A-5d95A:
undetectable		 5zw4A-5d95A:
20.44