SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d9n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.72A 1jnoA-5d9nA:
undetectable		 1jnoA-5d9nA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.72A 1jnoB-5d9nA:
undetectable		 1jnoB-5d9nA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.87A 1jo3A-5d9nA:
undetectable		 1jo3A-5d9nA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.87A 1jo3B-5d9nA:
undetectable		 1jo3B-5d9nA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.89A 1jo4A-5d9nA:
undetectable		 1jo4A-5d9nA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.89A 1jo4B-5d9nA:
undetectable		 1jo4B-5d9nA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.78A 1magA-5d9nA:
undetectable		 1magA-5d9nA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.78A 1magB-5d9nA:
undetectable		 1magB-5d9nA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.74A 1ng8A-5d9nA:
undetectable		 1ng8A-5d9nA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.73A 1ng8B-5d9nA:
undetectable		 1ng8B-5d9nA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.83A 1nruA-5d9nA:
undetectable		 1nruA-5d9nA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 ALA A  32
VAL A  73
TRP A  89
 None
 0.83A 1nruB-5d9nA:
undetectable		 1nruB-5d9nA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		4 / 5 GLN A 236
TRP A 141
GLU A 158
LEU A 155
 None
 1.30A 1ulvA-5d9nA:
undetectable		 1ulvA-5d9nA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 LYS A 214
ASP A 253
ASP A 241
 XYS  A 408 ( 2.9A)
None
XYS  A 408 ( 3.4A)
 1.01A 2br4D-5d9nA:
undetectable		 2br4D-5d9nA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		4 / 7 ARG A 194
GLU A  10
ASN A 231
ALA A  13
 None
 1.47A 2ejgB-5d9nA:
undetectable		 2ejgB-5d9nA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		4 / 5 LEU A 148
ILE A  71
ILE A  96
ALA A  95
 None
 0.77A 2i2zA-5d9nA:
undetectable		 2i2zA-5d9nA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		4 / 4 LEU A 148
ILE A  71
ILE A  96
ALA A  95
 None
 0.82A 2i30A-5d9nA:
undetectable		 2i30A-5d9nA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		5 / 12 ASN A 161
GLU A 162
HIS A 238
GLU A 280
TRP A 324
 None
XYS  A 408 ( 3.7A)
None
CA  A 401 ( 4.9A)
None
 0.60A 2v3dA-5d9nA:
7.4		 2v3dA-5d9nA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		4 / 6 PRO A 275
ILE A 277
ASN A 204
LEU A 156
 None
 1.28A 2wekB-5d9nA:
undetectable		 2wekB-5d9nA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		4 / 8 HIS A 284
ILE A 327
VAL A 343
GLN A 306
 None
 0.71A 3fi0G-5d9nA:
undetectable		 3fi0G-5d9nA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		5 / 12 GLY A  65
LYS A 312
ALA A 350
ASP A 316
ASN A  67
 None
 1.20A 3qowA-5d9nA:
undetectable		 3qowA-5d9nA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		5 / 9 ARG A 333
ALA A  68
GLY A 279
PRO A  72
LEU A  26
 None
 1.10A 3u7sB-5d9nA:
undetectable		 3u7sB-5d9nA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		4 / 7 ILE A 206
ASN A 208
GLU A 158
MET A 347
 None
 1.07A 4g0vA-5d9nA:
undetectable		 4g0vA-5d9nA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		3 / 3 PRO A  72
ASN A 161
HIS A 238
 None
 1.03A 4ma3H-5d9nA:
undetectable
4ma3L-5d9nA:
undetectable		 4ma3H-5d9nA:
19.66
4ma3L-5d9nA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		5 / 9 VAL A  97
VAL A  93
ILE A 144
PHE A 157
LEU A 155
 None
 1.41A 5e4dA-5d9nA:
undetectable		 5e4dA-5d9nA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		5 / 7 ILE A 263
THR A 321
ILE A 278
SER A 319
LEU A 260
 XYS  A 410 ( 4.7A)
None
None
None
None
 1.15A 5fukA-5d9nA:
undetectable
5fukB-5d9nA:
undetectable		 5fukA-5d9nA:
22.78
5fukB-5d9nA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5d9n B-1,4-ENDOGLUCANASE
(Prevotella
bryantii) 		5 / 12 VAL A  97
ALA A 107
VAL A 109
GLY A  23
PHE A 328
 None
 1.13A 5igiA-5d9nA:
undetectable		 5igiA-5d9nA:
21.39