SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5d9q NIH45-46 SINGLE
CHAIN FV
(Homo
sapiens) 		4 / 5 LEU D 276
PHE D 260
VAL D 298
ALA D 219
 None
 1.20A 2cizA-5d9qD:
undetectable		 2cizA-5d9qD:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 5d9q NIH45-46 SINGLE
CHAIN FV
(Homo
sapiens) 		4 / 6 HIS D 106
TYR D 234
GLY D  95
LYS D  96
 None
 1.45A 2i30A-5d9qD:
undetectable		 2i30A-5d9qD:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5d9q NIH45-46 SINGLE
CHAIN FV
(Homo
sapiens) 		4 / 7 PRO D  45
TYR D 234
PRO D 242
TYR D 285
 None
 0.88A 2ombC-5d9qD:
undetectable
2ombD-5d9qD:
undetectable		 2ombC-5d9qD:
23.05
2ombD-5d9qD:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5d9q NIH45-46 SINGLE
CHAIN FV
(Homo
sapiens) 		4 / 6 GLN D 235
TYR D 284
GLN D 206
ILE D 221
 None
 1.27A 3peoG-5d9qD:
undetectable		 3peoG-5d9qD:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5d9q NIH45-46 SINGLE
CHAIN FV
(Homo
sapiens) 		4 / 8 VAL D 298
LEU D 213
LEU D 276
ILE D 220
 None
 0.94A 3u5kC-5d9qD:
undetectable		 3u5kC-5d9qD:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5d9q NIH45-46 SINGLE
CHAIN FV
(Homo
sapiens) 		3 / 3 SER D 228
GLY D 229
GLN D 288
 None
 0.50A 3v4tH-5d9qD:
undetectable		 3v4tH-5d9qD:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 5d9q NIH45-46 SINGLE
CHAIN FV
(Homo
sapiens) 		3 / 3 ASN D 270
SER D 222
ARG D 224
 None
 0.88A 5b2qA-5d9qD:
undetectable		 5b2qA-5d9qD:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5d9q NIH45-46 SINGLE
CHAIN FV
(Homo
sapiens) 		4 / 4 LEU D  30
TYR D  97
PRO D  33
ILE D  34
 None
 1.26A 5esgA-5d9qD:
undetectable		 5esgA-5d9qD:
17.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 5d9q NIH45-46 SINGLE
CHAIN FV
(Homo
sapiens) 		3 / 3 TYR D  59
GLY D  65
THR D  68
 None
 0.00A 6cjkB-5d9qD:
undetectable		 6cjkB-5d9qD:
30.77