SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d9t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d9t DEHYDROASCORBATE
REDUCTASE
(Oryza
sativa) 		5 / 12 THR A  92
SER A 148
LEU A 131
VAL A 180
HIS A 134
 None
 1.40A 3u9fB-5d9tA:
undetectable
3u9fC-5d9tA:
undetectable		 3u9fB-5d9tA:
20.24
3u9fC-5d9tA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d9t DEHYDROASCORBATE
REDUCTASE
(Oryza
sativa) 		5 / 12 HIS A 134
THR A  92
SER A 148
LEU A 131
VAL A 180
 None
 1.37A 3u9fJ-5d9tA:
undetectable
3u9fL-5d9tA:
undetectable		 3u9fJ-5d9tA:
20.24
3u9fL-5d9tA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_A_CP6A201_1
(DIHYDROFOLATE
REDUCTASE)		 5d9t DEHYDROASCORBATE
REDUCTASE
(Oryza
sativa) 		5 / 10 ILE A  71
ASP A  67
THR A  29
LEU A  30
ILE A  77
 None
 1.18A 4km0A-5d9tA:
undetectable		 4km0A-5d9tA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5d9t DEHYDROASCORBATE
REDUCTASE
(Oryza
sativa) 		5 / 12 LEU A  30
ILE A  81
ILE A  77
GLY A  65
VAL A  62
 None
 0.99A 4nkvA-5d9tA:
undetectable		 4nkvA-5d9tA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5d9t DEHYDROASCORBATE
REDUCTASE
(Oryza
sativa) 		5 / 12 LEU A  30
ILE A  81
ILE A  77
GLY A  65
VAL A  62
 None
 0.98A 4nkvB-5d9tA:
undetectable		 4nkvB-5d9tA:
18.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D9W_A_ASCA301_0
(DEHYDROASCORBATE
REDUCTASE)		 5d9t DEHYDROASCORBATE
REDUCTASE
(Oryza
sativa) 		8 / 9 LYS A   8
ASP A  19
PRO A  21
PHE A 104
HIS A 160
GLY A 206
TRP A 207
LYS A 210
 None
 0.31A 5d9wA-5d9tA:
37.3		 5d9wA-5d9tA:
99.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 5d9t DEHYDROASCORBATE
REDUCTASE
(Oryza
sativa) 		4 / 8 THR A 108
TRP A 207
HIS A 160
PHE A  22
 None
 1.25A 5v4vA-5d9tA:
undetectable		 5v4vA-5d9tA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 5d9t DEHYDROASCORBATE
REDUCTASE
(Oryza
sativa) 		4 / 8 THR A 108
TRP A 207
HIS A 160
PHE A  22
 None
 1.24A 5v4vB-5d9tA:
undetectable		 5v4vB-5d9tA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5d9t DEHYDROASCORBATE
REDUCTASE
(Oryza
sativa) 		3 / 3 GLY A  18
VAL A   5
MET A  39
 None
 0.53A 5ycpA-5d9tA:
undetectable		 5ycpA-5d9tA:
14.93