SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5da8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		5 / 9 ILE A  99
LEU A 426
VAL A 124
ALA A 509
LEU A 505
 None
 1.10A 1e7bA-5da8A:
undetectable		 1e7bA-5da8A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		6 / 11 PHE A   8
ALA A  12
VAL A 107
LEU A 104
ALA A 512
LEU A  16
 None
 1.39A 1jinA-5da8A:
undetectable		 1jinA-5da8A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		5 / 11 VAL A 107
LEU A 104
GLY A 103
ILE A  99
THR A 517
 None
 1.17A 3bjwB-5da8A:
undetectable		 3bjwB-5da8A:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		5 / 12 VAL A 107
LEU A 104
GLY A 103
ILE A  99
THR A 517
 None
 1.06A 3bjwF-5da8A:
undetectable		 3bjwF-5da8A:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		5 / 11 VAL A 107
LEU A 104
GLY A 103
ILE A  99
THR A 517
 None
 1.17A 3bjwH-5da8A:
undetectable		 3bjwH-5da8A:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		4 / 5 PRO A 497
VAL A 500
THR A  30
GLY A  53
 None
 1.18A 3elzB-5da8A:
undetectable		 3elzB-5da8A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		4 / 7 VAL A 470
LYS A 469
TYR A 486
GLU A 484
 None
 1.29A 3hs4A-5da8A:
undetectable		 3hs4A-5da8A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		4 / 5 VAL A 177
LEU A 379
ILE A 158
ALA A 399
 None
 0.85A 3n8yB-5da8A:
0.9		 3n8yB-5da8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		5 / 9 ALA A 218
ILE A 332
ILE A 249
ILE A 325
ILE A 323
 None
 0.94A 3s45A-5da8A:
undetectable		 3s45A-5da8A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 416
VAL A 500
ASP A 496
GLY A 478
ALA A 492
 None
 1.10A 3sugA-5da8A:
undetectable		 3sugA-5da8A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		4 / 6 GLY A 414
VAL A 495
ASP A 496
THR A 501
 None
 0.86A 3vqrA-5da8A:
undetectable		 3vqrA-5da8A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		4 / 5 GLY A 414
VAL A 495
ASP A 496
THR A 501
 None
 0.87A 3vqrB-5da8A:
undetectable		 3vqrB-5da8A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		5 / 12 LEU A 489
VAL A 413
ASP A 476
GLY A 475
ILE A 420
 None
 0.98A 4xdrA-5da8A:
undetectable		 4xdrA-5da8A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		5 / 12 ALA A  78
ALA A 504
THR A 501
THR A  90
PRO A 450
 None
None
None
SO4  A 601 (-3.6A)
None
 1.19A 5k9dA-5da8A:
undetectable		 5k9dA-5da8A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		3 / 3 ALA A 111
GLN A 436
THR A 438
 None
 0.75A 5n0oA-5da8A:
undetectable		 5n0oA-5da8A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5da8 60 KDA CHAPERONIN
(Chlorobaculum
tepidum) 		4 / 7 ALA A 399
THR A 403
ILE A 144
ALA A 145
 None
 0.93A 6ma7A-5da8A:
undetectable		 6ma7A-5da8A:
10.04