SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5daa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5daa D-AMINO ACID
AMINOTRANSFERASE
(Bacillus
sp.
YM-1) 		4 / 4 LEU A 147
GLY A  27
GLY A  29
THR A  92
 None
 0.88A 3si7A-5daaA:
undetectable		 3si7A-5daaA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5daa D-AMINO ACID
AMINOTRANSFERASE
(Bacillus
sp.
YM-1) 		4 / 6 ILE A 144
ALA A  53
ARG A  50
ASP A 207
 None
None
PLP  A 285 (-2.7A)
None
 1.06A 6hu9m-5daaA:
undetectable
6hu9q-5daaA:
undetectable		 6hu9m-5daaA:
17.59
6hu9q-5daaA:
18.71