SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5daj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZF_A_TMQA170_1
(DIHYDROFOLATE
REDUCTASE)		 5daj NALD
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  19
HIS A  56
LEU A  57
LEU A  33
ALA A  14
 None
 1.06A 1bzfA-5dajA:
undetectable		 1bzfA-5dajA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5daj NALD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  15
ALA A  18
ALA A  19
ALA A  39
HIS A  56
 None
 1.01A 1fbyA-5dajA:
undetectable		 1fbyA-5dajA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5daj NALD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  15
ALA A  18
ALA A  19
ALA A  39
HIS A  56
 None
 0.99A 1fbyB-5dajA:
undetectable		 1fbyB-5dajA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 5daj NALD
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  76
SER A  87
ASP A  90
PHE A 144
 None
 1.28A 1ismB-5dajA:
undetectable		 1ismB-5dajA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 5daj NALD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  15
ALA A  18
ALA A  19
ALA A  39
HIS A  56
 None
 1.03A 1xiuB-5dajA:
undetectable		 1xiuB-5dajA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 5daj NALD
(Pseudomonas
aeruginosa) 		5 / 10 GLU A  60
MET A  61
ASN A  63
THR A  31
LEU A  24
 None
 1.34A 2ha6A-5dajA:
undetectable		 2ha6A-5dajA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_B_SCKB952_1
(ACETYLCHOLINESTERASE)		 5daj NALD
(Pseudomonas
aeruginosa) 		5 / 10 GLU A  60
MET A  61
ASN A  63
THR A  31
LEU A  24
 None
 1.35A 2ha6B-5dajA:
undetectable		 2ha6B-5dajA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5daj NALD
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 108
GLU A  20
PHE A  23
VAL A  42
 None
 0.89A 4a97A-5dajA:
3.6		 4a97A-5dajA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5daj NALD
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 108
GLU A  20
PHE A  23
VAL A  42
 None
 0.90A 4a97D-5dajA:
4.0		 4a97D-5dajA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 5daj NALD
(Pseudomonas
aeruginosa) 		4 / 8 LEU A  88
PHE A 198
TRP A 205
PRO A  84
 None
 1.12A 4j7uD-5dajA:
undetectable		 4j7uD-5dajA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5H_A_ACTA1229_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 5daj NALD
(Pseudomonas
aeruginosa) 		4 / 4 VAL A  28
GLU A 121
THR A 119
GLU A 117
 None
 1.46A 5g5hA-5dajA:
undetectable		 5g5hA-5dajA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5daj NALD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  15
ALA A  18
ALA A  19
ALA A  39
HIS A  56
 None
 0.97A 6a60D-5dajA:
undetectable		 6a60D-5dajA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5daj NALD
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 144
LEU A 201
VAL A 202
CYH A 149
ARG A 146
 None
 1.16A 6bxmA-5dajA:
undetectable		 6bxmA-5dajA:
20.72