SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dbj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		5 / 9 VAL E  33
GLY E  13
SER E  18
LEU E 130
LEU E 333
 None
FAD  E 501 ( 4.9A)
None
None
None
 1.49A 2j2pB-5dbjE:
undetectable
2j2pC-5dbjE:
undetectable		 2j2pB-5dbjE:
19.09
2j2pC-5dbjE:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		5 / 9 LEU E  24
ILE E 343
GLY E 341
SER E  22
SER E  18
 None
 1.14A 2qmmA-5dbjE:
undetectable		 2qmmA-5dbjE:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		3 / 3 ARG E  99
GLU E 102
ASP E 221
 None
 0.66A 3g2oA-5dbjE:
undetectable		 3g2oA-5dbjE:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		4 / 6 PHE E 211
ALA E 283
ALA E 216
LEU E 280
 None
 1.05A 4dtzB-5dbjE:
undetectable		 4dtzB-5dbjE:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		4 / 6 ARG E 291
ARG E 123
ASP E 122
ASP E 127
 None
FAD  E 501 (-2.9A)
None
None
 1.36A 4kcnB-5dbjE:
undetectable		 4kcnB-5dbjE:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		5 / 12 VAL E 312
ALA E 318
SER E 340
LEU E  24
VAL E 177
 None
 1.38A 4kyaB-5dbjE:
undetectable		 4kyaB-5dbjE:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		5 / 12 VAL E 312
ALA E 318
SER E 340
LEU E  24
VAL E 177
 None
 1.37A 4kyaH-5dbjE:
undetectable		 4kyaH-5dbjE:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		3 / 3 HIS E 229
TRP E 237
SER E 215
 None
 0.90A 4lrhD-5dbjE:
undetectable		 4lrhD-5dbjE:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		4 / 7 LEU E 104
GLU E 107
ILE E 103
VAL E 389
 None
 1.19A 4tvtA-5dbjE:
undetectable		 4tvtA-5dbjE:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		4 / 6 VAL E 312
LEU E  24
ALA E 339
ALA E  16
 None
None
None
FAD  E 501 (-3.2A)
 0.68A 4zf8A-5dbjE:
undetectable		 4zf8A-5dbjE:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		4 / 7 SER E  18
ALA E  21
GLY E 135
VAL E 141
 None
 0.71A 5fpdA-5dbjE:
undetectable		 5fpdA-5dbjE:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		5 / 11 TYR E 299
ASP E 322
VAL E  44
ILE E 324
PHE E 320
 FAD  E 501 ( 4.3A)
None
FAD  E 501 (-4.7A)
None
FAD  E 501 ( 4.2A)
 1.17A 5hw8D-5dbjE:
undetectable		 5hw8D-5dbjE:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		5 / 11 TYR E 299
ASP E 322
VAL E  44
ILE E 324
PHE E 320
 FAD  E 501 ( 4.3A)
None
FAD  E 501 (-4.7A)
None
FAD  E 501 ( 4.2A)
 1.17A 5hw8E-5dbjE:
undetectable		 5hw8E-5dbjE:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		4 / 8 TYR E 299
ASP E 322
VAL E  44
PHE E 320
 FAD  E 501 ( 4.3A)
None
FAD  E 501 (-4.7A)
FAD  E 501 ( 4.2A)
 0.76A 5hw8H-5dbjE:
undetectable		 5hw8H-5dbjE:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		3 / 3 THR E 244
PRO E  71
ASP E 224
 None
 0.93A 5l8dB-5dbjE:
undetectable		 5l8dB-5dbjE:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		3 / 3 THR E 244
PRO E  71
ASP E 224
 None
 0.93A 5mwuB-5dbjE:
undetectable		 5mwuB-5dbjE:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		5 / 11 GLY E  12
GLU E  35
LYS E  36
LEU E 185
ASN E 183
 FAD  E 501 (-3.1A)
FAD  E 501 (-2.4A)
FAD  E 501 (-3.4A)
FAD  E 501 ( 4.1A)
FAD  E 501 (-3.8A)
 1.23A 5x6yA-5dbjE:
undetectable		 5x6yA-5dbjE:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		3 / 3 TYR E 299
ASP E 196
ASP E 322
 FAD  E 501 ( 4.3A)
None
None
 0.67A 5x6yA-5dbjE:
undetectable		 5x6yA-5dbjE:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		4 / 5 GLY E  84
ASP E  82
ARG E  99
GLN E 390
 None
 1.49A 5zrfB-5dbjE:
undetectable		 5zrfB-5dbjE:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		5 / 12 TYR E 378
PHE E 374
ALA E 387
ALA E 101
LEU E 402
 None
 1.22A 6aybA-5dbjE:
undetectable		 6aybA-5dbjE:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		3 / 3 SER E 326
SER E  47
ALA E  77
 FAD  E 501 (-3.4A)
FAD  E 501 (-4.9A)
None
 0.54A 6dwnC-5dbjE:
0.0		 6dwnC-5dbjE:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		5 / 12 MET E 175
ALA E 173
TYR E   6
PHE E  34
VAL E 160
 None
 1.30A 6hu9N-5dbjE:
undetectable		 6hu9N-5dbjE:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5dbj FADH2-DEPENDENT
HALOGENASE PLTA
(Pseudomonas
protegens) 		5 / 10 SER E 249
GLY E  14
SER E  18
ALA E 134
VAL E 329
 None
FAD  E 501 (-3.4A)
None
None
FAD  E 501 (-3.7A)
 1.25A 6hu9L-5dbjE:
undetectable
6hu9P-5dbjE:
undetectable
6hu9T-5dbjE:
undetectable		 6hu9L-5dbjE:
23.24
6hu9P-5dbjE:
18.38
6hu9T-5dbjE:
10.90