SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dbn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KCE_B_D16B568_1 (THYMIDYLATE SYNTHASE)	5dbn	ACETATE COA-TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	SER B 132 LEU B 23 GLY B 24 VAL B 31 ALA B 8	None	1.24A	2kceB-5dbnB: undetectable	2kceB-5dbnB: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_A_CELA682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	5dbn	ACETATE COA-TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	VAL B 21 LEU B 43 VAL B 11 ALA B 12 LEU B 35	None	1.06A	3ln1A-5dbnB: undetectable	3ln1A-5dbnB: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_B_CELB682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	5dbn	ACETATE COA-TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	VAL B 21 LEU B 43 VAL B 11 ALA B 12 LEU B 35	None	1.06A	3ln1B-5dbnB: undetectable	3ln1B-5dbnB: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	5dbn	ACETATE COA-TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	VAL B 21 LEU B 43 VAL B 11 ALA B 12 LEU B 35	None	1.05A	3ln1C-5dbnB: undetectable	3ln1C-5dbnB: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_D_CELD682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	5dbn	ACETATE COA-TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	VAL B 21 LEU B 43 VAL B 11 ALA B 12 LEU B 35	None	1.06A	3ln1D-5dbnB: undetectable	3ln1D-5dbnB: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PGH_D_FLPD701_1 (CYCLOOXYGENASE-2)	5dbn	ACETATE COA-TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	VAL B 21 LEU B 43 VAL B 11 ALA B 12 LEU B 35	None	1.07A	3pghD-5dbnB: undetectable	3pghD-5dbnB: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKR_B_ID8B602_1 (PROSTAGLANDIN G/H SYNTHASE 2)	5dbn	ACETATE COA-TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 12	VAL B 21 LEU B 43 VAL B 11 ALA B 12 LEU B 35	None	1.05A	5ikrB-5dbnB: undetectable	5ikrB-5dbnB: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NUK_A_Z80A201_1 (BETA-LACTOGLOBULIN)	5dbn	ACETATE COA-TRANSFERASE SUBUNIT BETA (Escherichia coli)	5 / 10	ALA B 163 VAL B 135 ILE B 93 ILE B 88 ALA B 160	None	1.22A	5nukA-5dbnB: undetectable	5nukA-5dbnB: 19.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2KCE_B_D16B568_1","THYMIDYLATE SYNTHASE","5dbn","ACETATE COA-TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"SER B 132;LEU B  23;GLY B  24;VAL B  31;ALA B   8","None","1.24A","2kceB-5dbnB:undetectable","2kceB-5dbnB:21.13"],["3LN1_A_CELA682_1","PROSTAGLANDIN G\/H SYNTHASE 2","5dbn","ACETATE COA-TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"VAL B  21;LEU B  43;VAL B  11;ALA B  12;LEU B  35","None","1.06A","3ln1A-5dbnB:undetectable","3ln1A-5dbnB:17.78"],["3LN1_B_CELB682_1","PROSTAGLANDIN G\/H SYNTHASE 2","5dbn","ACETATE COA-TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"VAL B  21;LEU B  43;VAL B  11;ALA B  12;LEU B  35","None","1.06A","3ln1B-5dbnB:undetectable","3ln1B-5dbnB:17.78"],["3LN1_C_CELC682_1","PROSTAGLANDIN G\/H SYNTHASE 2","5dbn","ACETATE COA-TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"VAL B  21;LEU B  43;VAL B  11;ALA B  12;LEU B  35","None","1.05A","3ln1C-5dbnB:undetectable","3ln1C-5dbnB:17.78"],["3LN1_D_CELD682_1","PROSTAGLANDIN G\/H SYNTHASE 2","5dbn","ACETATE COA-TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"VAL B  21;LEU B  43;VAL B  11;ALA B  12;LEU B  35","None","1.06A","3ln1D-5dbnB:undetectable","3ln1D-5dbnB:17.78"],["3PGH_D_FLPD701_1","CYCLOOXYGENASE-2","5dbn","ACETATE COA-TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"VAL B  21;LEU B  43;VAL B  11;ALA B  12;LEU B  35","None","1.07A","3pghD-5dbnB:undetectable","3pghD-5dbnB:16.90"],["5IKR_B_ID8B602_1","PROSTAGLANDIN G\/H SYNTHASE 2","5dbn","ACETATE COA-TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"VAL B  21;LEU B  43;VAL B  11;ALA B  12;LEU B  35","None","1.05A","5ikrB-5dbnB:undetectable","5ikrB-5dbnB:15.61"],["5NUK_A_Z80A201_1","BETA-LACTOGLOBULIN","5dbn","ACETATE COA-TRANSFERASE SUBUNIT BETA","Escherichia coli",5,"ALA B 163;VAL B 135;ILE B  93;ILE B  88;ALA B 160","None","1.22A","5nukA-5dbnB:undetectable","5nukA-5dbnB:19.90"]]