SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dcf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		5 / 11 LEU A  72
VAL A  58
TYR A 170
LEU A  38
HIS A 172
 None
 1.36A 1kt6A-5dcfA:
undetectable		 1kt6A-5dcfA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		4 / 4 TYR A  34
LEU A  30
LEU A  13
HIS A 144
 None
 1.42A 2x7hB-5dcfA:
undetectable		 2x7hB-5dcfA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		3 / 3 SER A 233
ARG A 237
GLN A 236
 None
 0.99A 2xnrA-5dcfA:
undetectable		 2xnrA-5dcfA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		4 / 8 GLY A 149
ARG A 177
LEU A 146
LEU A 145
 None
 0.93A 3nbqB-5dcfA:
undetectable		 3nbqB-5dcfA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		4 / 5 GLU A  10
GLY A 242
TYR A  34
GLU A  31
 None
 1.46A 3w9tA-5dcfA:
undetectable		 3w9tA-5dcfA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		4 / 5 GLU A  10
GLY A 242
TYR A  34
GLU A  31
 None
 1.46A 3w9tC-5dcfA:
undetectable		 3w9tC-5dcfA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		4 / 5 GLU A  10
GLY A 242
TYR A  34
GLU A  31
 None
 1.46A 3w9tD-5dcfA:
undetectable		 3w9tD-5dcfA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		4 / 5 GLU A  10
GLY A 242
TYR A  34
GLU A  31
 None
 1.45A 3w9tG-5dcfA:
undetectable		 3w9tG-5dcfA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		3 / 3 GLU A 176
HIS A 172
VAL A 155
 None
 0.46A 5trqB-5dcfA:
undetectable		 5trqB-5dcfA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		4 / 7 ASP A 151
GLY A  56
GLY A  73
VAL A  77
 None
 0.92A 6ekzA-5dcfA:
undetectable		 6ekzA-5dcfA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK
(Escherichia
coli) 		4 / 8 ARG A 117
HIS A 116
ASP A  26
GLU A  23
 None
 1.11A 6mn4A-5dcfA:
undetectable		 6mn4A-5dcfA:
24.67