SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dcp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 5dcp FILAMIN-B
(Homo
sapiens) 		4 / 6 LEU A1891
ASP A1855
LEU A1854
GLY A1853
 None
 0.95A 1n13H-5dcpA:
undetectable
1n13K-5dcpA:
undetectable		 1n13H-5dcpA:
20.44
1n13K-5dcpA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5dcp FILAMIN-B
(Homo
sapiens) 		4 / 7 LEU A1891
ASP A1855
LEU A1854
GLY A1853
 None
 0.91A 2qqcD-5dcpA:
undetectable
2qqcE-5dcpA:
undetectable		 2qqcD-5dcpA:
20.44
2qqcE-5dcpA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 5dcp FILAMIN-B
(Homo
sapiens) 		4 / 9 ILE A1800
PHE A1747
VAL A1786
GLU A1775
 None
 0.87A 2vufA-5dcpA:
undetectable		 2vufA-5dcpA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 5dcp FILAMIN-B
(Homo
sapiens) 		4 / 7 VAL A1786
PHE A1747
VAL A1832
ILE A1807
 None
 0.82A 3zjqA-5dcpA:
undetectable		 3zjqA-5dcpA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 5dcp FILAMIN-B
(Homo
sapiens) 		4 / 7 VAL A1832
PHE A1814
VAL A1764
ILE A1751
 None
 0.86A 3zjqA-5dcpA:
undetectable		 3zjqA-5dcpA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 5dcp FILAMIN-B
(Homo
sapiens) 		4 / 7 VAL A1786
PHE A1747
VAL A1832
ILE A1807
 None
 0.83A 3zjqB-5dcpA:
undetectable		 3zjqB-5dcpA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 5dcp FILAMIN-B
(Homo
sapiens) 		4 / 7 VAL A1832
PHE A1814
VAL A1764
ILE A1751
 None
 0.84A 3zjqB-5dcpA:
undetectable		 3zjqB-5dcpA:
22.75