SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dcq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 5dcq FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
equi) 		4 / 7 LEU D  66
LEU D   2
LYS D  23
TYR D   4
 None
 1.04A 1gtiD-5dcqD:
undetectable		 1gtiD-5dcqD:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 5dcq FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
equi) 		4 / 7 LEU D  66
LEU D   2
LYS D  23
TYR D   4
 None
 1.05A 1gtiE-5dcqD:
undetectable		 1gtiE-5dcqD:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		6 / 12 THR A  35
ALA A  34
LEU A  49
LEU A  53
ILE A 102
GLY A  72
 None
 1.49A 1qknA-5dcqA:
undetectable		 1qknA-5dcqA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		5 / 12 THR A 125
LEU A  99
ILE A 112
MET A 142
TYR A 160
 None
 1.13A 3gwxA-5dcqA:
undetectable		 3gwxA-5dcqA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		5 / 11 ALA A  67
ILE A  71
GLY A  41
LEU A  49
ALA A  45
 None
 1.20A 3kw2A-5dcqA:
undetectable		 3kw2A-5dcqA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		5 / 11 ALA A  98
ILE A 102
GLY A  72
LEU A  80
ALA A  76
 None
 1.21A 3kw2A-5dcqA:
undetectable		 3kw2A-5dcqA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		5 / 11 ALA A  67
ILE A  71
GLY A  41
LEU A  49
ALA A  45
 None
 1.21A 3kw2B-5dcqA:
undetectable		 3kw2B-5dcqA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		5 / 11 ALA A  98
ILE A 102
GLY A  72
LEU A  80
ALA A  76
 None
 1.23A 3kw2B-5dcqA:
undetectable		 3kw2B-5dcqA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 5dcq FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
equi) 		4 / 7 ASP D  47
GLN D  48
TYR D  16
PRO D  46
 None
 1.20A 3l2vA-5dcqD:
undetectable		 3l2vA-5dcqD:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		5 / 12 GLY A  69
GLY A  72
VAL A  77
ALA A  95
ALA A  94
 None
 1.01A 3mteA-5dcqA:
undetectable		 3mteA-5dcqA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		5 / 12 GLY A  69
GLY A  72
VAL A  77
ALA A  95
ALA A  94
 None
 1.01A 3p2kD-5dcqA:
undetectable		 3p2kD-5dcqA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		4 / 6 LEU A  22
LEU A  49
ILE A  71
TRP A  66
 None
 1.00A 4do3B-5dcqA:
undetectable		 4do3B-5dcqA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 5dcq FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
equi) 		3 / 3 ASN D 120
SER D 123
SER D 122
 None
 0.68A 5gsnA-5dcqD:
undetectable		 5gsnA-5dcqD:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		4 / 8 LEU A  53
GLU A  78
LEU A  99
ILE A 102
 None
 1.01A 5mzjA-5dcqA:
undetectable		 5mzjA-5dcqA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)
(synthetic
construct) 		4 / 8 GLY A  69
LEU A  68
ALA A  76
GLU A  74
 None
 0.77A 6mdqA-5dcqA:
undetectable		 6mdqA-5dcqA:
21.02