SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dd4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5dd4 TRANSCRIPTIONAL
REGULATOR ARAR
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 151
PRO A 150
GLU A 149
ARG A 218
 None
 1.30A 1oniA-5dd4A:
undetectable
1oniC-5dd4A:
undetectable		 1oniA-5dd4A:
21.14
1oniC-5dd4A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5dd4 TRANSCRIPTIONAL
REGULATOR ARAR
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 218
ILE A 151
PRO A 150
GLU A 149
 None
 1.35A 1oniG-5dd4A:
undetectable
1oniH-5dd4A:
undetectable		 1oniG-5dd4A:
21.14
1oniH-5dd4A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5dd4 TRANSCRIPTIONAL
REGULATOR ARAR
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 218
GLU A 149
ASN A 154
PRO A 150
 None
 1.29A 2ejgB-5dd4A:
undetectable		 2ejgB-5dd4A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5dd4 TRANSCRIPTIONAL
REGULATOR ARAR
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 218
GLU A 149
ASN A 154
PRO A 150
 None
 1.14A 2zgwA-5dd4A:
undetectable		 2zgwA-5dd4A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 5dd4 TRANSCRIPTIONAL
REGULATOR ARAR
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE A 223
LEU A 156
PHE A  22
MET A 189
PHE A 182
 None
 1.38A 3nuvA-5dd4A:
undetectable		 3nuvA-5dd4A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 5dd4 TRANSCRIPTIONAL
REGULATOR ARAR
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A  14
ILE A  18
GLY A  47
PHE A  49
 None
 0.61A 5alcL-5dd4A:
undetectable		 5alcL-5dd4A:
22.09