SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dd8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 5dd8 TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Deinococcus
radiodurans) 		5 / 10 GLY A  66
SER A  65
LEU A 139
THR A  61
LEU A 143
 None
 1.48A 1a8uA-5dd8A:
undetectable		 1a8uA-5dd8A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 5dd8 TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Deinococcus
radiodurans) 		5 / 10 LEU A  46
LEU A  42
LYS A   8
LEU A  12
ALA A  10
 None
 1.33A 1ie4A-5dd8A:
undetectable
1ie4C-5dd8A:
undetectable		 1ie4A-5dd8A:
22.50
1ie4C-5dd8A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 5dd8 TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Deinococcus
radiodurans) 		4 / 7 LEU A  46
LYS A   8
LEU A  12
ALA A  10
 None
 1.14A 1sn0B-5dd8A:
undetectable
1sn0D-5dd8A:
undetectable		 1sn0B-5dd8A:
22.09
1sn0D-5dd8A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 5dd8 TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Deinococcus
radiodurans) 		4 / 7 LYS A   8
LEU A  12
ALA A  10
LEU A  46
 None
 1.10A 1sn0B-5dd8A:
undetectable
1sn0D-5dd8A:
undetectable		 1sn0B-5dd8A:
22.09
1sn0D-5dd8A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 5dd8 TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Deinococcus
radiodurans) 		4 / 5 LEU A  78
SER A  81
ARG A  80
LEU A  87
 None
None
CL  A 201 (-4.0A)
None
 1.34A 3onnA-5dd8A:
undetectable		 3onnA-5dd8A:
19.32