SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ddv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.14A 1hrkA-5ddvA:
undetectable		 1hrkA-5ddvA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.17A 1hrkB-5ddvA:
undetectable		 1hrkB-5ddvA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.16A 2hrcA-5ddvA:
undetectable		 2hrcA-5ddvA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.16A 2hrcB-5ddvA:
undetectable		 2hrcB-5ddvA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.20A 2po5A-5ddvA:
2.4		 2po5A-5ddvA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 11 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.19A 2po5B-5ddvA:
undetectable		 2po5B-5ddvA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.19A 2po7A-5ddvA:
2.5		 2po7A-5ddvA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.17A 2po7B-5ddvA:
2.6		 2po7B-5ddvA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		4 / 6 ILE A  53
PRO A  31
LEU A  37
ILE A  33
 None
 1.04A 2q83B-5ddvA:
undetectable		 2q83B-5ddvA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.16A 2qd4B-5ddvA:
2.5		 2qd4B-5ddvA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.25A 3aqiB-5ddvA:
undetectable		 3aqiB-5ddvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		4 / 7 LYS A  92
TYR A  88
LYS A 171
GLU A 175
 None
 1.25A 3hs4A-5ddvA:
undetectable		 3hs4A-5ddvA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		6 / 12 GLY A  79
GLU A  55
GLY A  80
ILE A   7
LEU A  51
VAL A  77
 None
 1.43A 3nk7B-5ddvA:
2.3		 3nk7B-5ddvA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU A 169
PHE A 164
LEU A  91
PRO A   8
VAL A  52
 None
 1.25A 3w1wB-5ddvA:
2.5		 3w1wB-5ddvA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 PHE A 164
VAL A 198
ALA A 187
GLU A 175
ALA A 172
 None
 1.20A 4fiaA-5ddvA:
undetectable		 4fiaA-5ddvA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 PHE A 164
VAL A 198
ALA A 187
GLU A 175
ALA A 172
 None
 1.20A 4fiaA-5ddvA:
undetectable		 4fiaA-5ddvA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		3 / 3 TYR A  68
HIS A  35
ARG A  38
 None
 1.03A 4htfA-5ddvA:
undetectable		 4htfA-5ddvA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Bacillus
subtilis) 		4 / 5 GLU A 117
VAL A 201
LEU A 130
HIS A 103
 None
 1.18A 6dyoA-5ddvA:
undetectable		 6dyoA-5ddvA:
16.88