SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dfv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5dfv FAB HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL C 409
LEU C 317
LEU C 407
THR C 321
GLU C 211
 None
 1.29A 1kw0A-5dfvC:
undetectable		 1kw0A-5dfvC:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5dfv FAB HEAVY CHAIN
(Mus
musculus) 		5 / 11 VAL C 409
LEU C 317
LEU C 407
THR C 321
GLU C 211
 None
 1.26A 1mmtA-5dfvC:
undetectable		 1mmtA-5dfvC:
20.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 5dfv FAB HEAVY CHAIN
(Mus
musculus) 		4 / 7 TRP C 212
ILE C 292
LEU C 397
TRP C 197
 None
 1.24A 1q0yH-5dfvC:
23.8
1q0yL-5dfvC:
19.3		 1q0yH-5dfvC:
71.62
1q0yL-5dfvC:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 5dfv FAB HEAVY CHAIN
(Mus
musculus) 		5 / 12 LEU C1024
VAL C1049
GLY C1043
VAL C1069
VAL C1067
 None
 0.91A 2ieoB-5dfvC:
undetectable		 2ieoB-5dfvC:
19.07