SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dhd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZD1_A_T27A557_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	5dhd	CHITINASE (Thermococcus kodakarensis)	5 / 12	VAL A 680 VAL A 655 TYR A 709 TYR A 679 TYR A 641	None None PE3 A 804 ( 3.9A) PE3 A 804 (-3.8A) None	1.17A	2zd1A-5dhdA: 1.4	2zd1A-5dhdA: 10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZG_A_NCAA302_0 (ADP-RIBOSYL CYCLASE 1)	5dhd	CHITINASE (Thermococcus kodakarensis)	4 / 7	GLU A 640 ASP A 642 TRP A 669 SER A 667	PE3 A 803 ( 4.6A) PE3 A 803 (-3.4A) None None	1.24A	3dzgA-5dhdA: undetectable	3dzgA-5dhdA: 17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZG_B_NCAB302_0 (ADP-RIBOSYL CYCLASE 1)	5dhd	CHITINASE (Thermococcus kodakarensis)	4 / 7	GLU A 640 ASP A 642 TRP A 669 SER A 667	PE3 A 803 ( 4.6A) PE3 A 803 (-3.4A) None None	1.24A	3dzgB-5dhdA: undetectable	3dzgB-5dhdA: 17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G1Q_A_T27A601_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	5dhd	CHITINASE (Thermococcus kodakarensis)	5 / 12	VAL A 680 VAL A 655 TYR A 709 TYR A 679 TYR A 641	None None PE3 A 804 ( 3.9A) PE3 A 804 (-3.8A) None	1.20A	4g1qA-5dhdA: 1.6	4g1qA-5dhdA: 10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IG3_A_T27A601_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	5dhd	CHITINASE (Thermococcus kodakarensis)	5 / 12	VAL A 680 VAL A 655 TYR A 709 TYR A 679 TYR A 641	None None PE3 A 804 ( 3.9A) PE3 A 804 (-3.8A) None	1.22A	4ig3A-5dhdA: undetectable	4ig3A-5dhdA: 10.99

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZD1_A_T27A557_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","5dhd","CHITINASE","Thermococcus kodakarensis",5,"VAL A 680;VAL A 655;TYR A 709;TYR A 679;TYR A 641","None;None;PE3 A 804 ( 3.9A);PE3 A 804 (-3.8A);None","1.17A","2zd1A-5dhdA:1.4","2zd1A-5dhdA:10.99"],["3DZG_A_NCAA302_0","ADP-RIBOSYL CYCLASE 1","5dhd","CHITINASE","Thermococcus kodakarensis",4,"GLU A 640;ASP A 642;TRP A 669;SER A 667","PE3 A 803 ( 4.6A);PE3 A 803 (-3.4A);None;None","1.24A","3dzgA-5dhdA:undetectable","3dzgA-5dhdA:17.94"],["3DZG_B_NCAB302_0","ADP-RIBOSYL CYCLASE 1","5dhd","CHITINASE","Thermococcus kodakarensis",4,"GLU A 640;ASP A 642;TRP A 669;SER A 667","PE3 A 803 ( 4.6A);PE3 A 803 (-3.4A);None;None","1.24A","3dzgB-5dhdA:undetectable","3dzgB-5dhdA:17.94"],["4G1Q_A_T27A601_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","5dhd","CHITINASE","Thermococcus kodakarensis",5,"VAL A 680;VAL A 655;TYR A 709;TYR A 679;TYR A 641","None;None;PE3 A 804 ( 3.9A);PE3 A 804 (-3.8A);None","1.20A","4g1qA-5dhdA:1.6","4g1qA-5dhdA:10.99"],["4IG3_A_T27A601_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","5dhd","CHITINASE","Thermococcus kodakarensis",5,"VAL A 680;VAL A 655;TYR A 709;TYR A 679;TYR A 641","None;None;PE3 A 804 ( 3.9A);PE3 A 804 (-3.8A);None","1.22A","4ig3A-5dhdA:undetectable","4ig3A-5dhdA:10.99"]]