SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dhx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1H8S_A_AICA1000_1 (MUTANT AL2 6E7P9G)	5dhx	ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN (Oryctolagus cuniculus)	7 / 12	TYR B 36 PHE B 101 TRP B 143 ASN B 145 VAL B 147 ALA B 205 TRP B 217	None	0.70A	1h8sA-5dhxB: 28.4	1h8sA-5dhxB: 51.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XRH_A_NIOA200_1 (PROTEIN HP0721)	5dhx	ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN (Oryctolagus cuniculus)	4 / 7	GLY B 136 ILE B 216 THR B 208 GLN B 111	None	0.96A	2xrhA-5dhxB: undetectable	2xrhA-5dhxB: 14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZM_A_SAMA401_0 (UNCHARACTERIZED PROTEIN MJ0883)	5dhx	ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN (Oryctolagus cuniculus)	5 / 12	PHE B 101 GLY B 103 VAL B 147 LEU B 89 PHE B 214	None	1.23A	2zzmA-5dhxB: undetectable	2zzmA-5dhxB: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BW4_B_SAMB301_1 (16S RRNA (ADENINE(1408)-N(1)) -METHYLTRANSFERASE)	5dhx	ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN (Oryctolagus cuniculus)	3 / 3	ASP B 207 GLU B 112 SER B 31	None	0.85A	5bw4B-5dhxB: undetectable	5bw4B-5dhxB: 22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5dhx	ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN (Oryctolagus cuniculus)	4 / 7	ALA B 200 THR B 199 VAL B 223 GLU B 197	None	0.73A	5ecmD-5dhxB: undetectable	5ecmD-5dhxB: 17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5dhx	ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN (Oryctolagus cuniculus)	4 / 7	ALA B 200 THR B 199 VAL B 223 GLU B 197	None	0.84A	5ecoD-5dhxB: undetectable	5ecoD-5dhxB: 17.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1H8S_A_AICA1000_1","MUTANT AL2 6E7P9G","5dhx","ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN","Oryctolagus cuniculus",7,"TYR B  36;PHE B 101;TRP B 143;ASN B 145;VAL B 147;ALA B 205;TRP B 217","None","0.70A","1h8sA-5dhxB:28.4","1h8sA-5dhxB:51.53"],["2XRH_A_NIOA200_1","PROTEIN HP0721","5dhx","ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN","Oryctolagus cuniculus",4,"GLY B 136;ILE B 216;THR B 208;GLN B 111","None","0.96A","2xrhA-5dhxB:undetectable","2xrhA-5dhxB:14.69"],["2ZZM_A_SAMA401_0","UNCHARACTERIZED PROTEIN MJ0883","5dhx","ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN","Oryctolagus cuniculus",5,"PHE B 101;GLY B 103;VAL B 147;LEU B  89;PHE B 214","None","1.23A","2zzmA-5dhxB:undetectable","2zzmA-5dhxB:19.72"],["5BW4_B_SAMB301_1","16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE","5dhx","ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN","Oryctolagus cuniculus",3,"ASP B 207;GLU B 112;SER B  31","None","0.85A","5bw4B-5dhxB:undetectable","5bw4B-5dhxB:22.57"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5dhx","ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN","Oryctolagus cuniculus",4,"ALA B 200;THR B 199;VAL B 223;GLU B 197","None","0.73A","5ecmD-5dhxB:undetectable","5ecmD-5dhxB:17.88"],["5ECO_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5dhx","ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, LIGHT CHAIN,ANTI-REV ANTIBODY FAB SINGLE-CHAIN VARIABLE FRAGMENT, HEAVY CHAIN","Oryctolagus cuniculus",4,"ALA B 200;THR B 199;VAL B 223;GLU B 197","None","0.84A","5ecoD-5dhxB:undetectable","5ecoD-5dhxB:17.88"]]