SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5di0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_1
(ALCOHOL
DEHYDROGENASE)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		4 / 4 GLU A 113
MET A 116
LEU A  77
SER A  78
 PG4  A 416 (-3.4A)
None
None
PG4  A 416 ( 4.0A)
 1.45A 1ee2B-5di0A:
undetectable		 1ee2B-5di0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		5 / 12 GLY A 130
GLY A  15
GLY A  14
PHE A  18
SER A 132
 PEG  A 406 (-3.5A)
PGE  A 413 ( 4.9A)
None
PEG  A 406 (-4.9A)
PGE  A 413 (-3.5A)
 1.11A 1xdsA-5di0A:
undetectable		 1xdsA-5di0A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		5 / 12 GLY A 130
GLY A  15
GLY A  14
PHE A  18
SER A 132
 PEG  A 406 (-3.5A)
PGE  A 413 ( 4.9A)
None
PEG  A 406 (-4.9A)
PGE  A 413 (-3.5A)
 1.09A 1xdsB-5di0A:
undetectable		 1xdsB-5di0A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		4 / 7 VAL A 153
ALA A 215
PRO A 275
TRP A 199
 None
 1.05A 2q6oA-5di0A:
undetectable		 2q6oA-5di0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		5 / 12 GLY A  51
GLY A  26
GLY A  22
LEU A 142
THR A 148
 None
PEG  A 410 (-4.1A)
None
None
None
 0.95A 2wa2B-5di0A:
undetectable		 2wa2B-5di0A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		4 / 7 LEU A 150
VAL A 153
GLY A 216
THR A 236
 None
 0.70A 2wd9A-5di0A:
undetectable		 2wd9A-5di0A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		4 / 8 LEU A 150
VAL A 153
GLY A 216
THR A 236
 None
 0.70A 2wd9B-5di0A:
undetectable		 2wd9B-5di0A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		4 / 7 PRO A  59
GLY A  57
ALA A  43
ALA A  46
 None
PEG  A 406 (-4.2A)
None
None
 0.80A 3ur0B-5di0A:
undetectable		 3ur0B-5di0A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		5 / 12 LEU A  88
ILE A   9
ILE A  91
ILE A 126
PHE A 139
 None
PEG  A 408 (-4.3A)
None
None
None
 1.06A 4rp8C-5di0A:
undetectable		 4rp8C-5di0A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		4 / 5 ARG A  52
GLY A  22
ALA A  27
GLY A 125
 PEG  A 409 (-3.8A)
None
PEG  A 410 ( 4.3A)
None
 0.87A 4u9uA-5di0A:
undetectable		 4u9uA-5di0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		4 / 5 ARG A  52
GLY A  22
ALA A  27
GLY A 125
 PEG  A 409 (-3.8A)
None
PEG  A 410 ( 4.3A)
None
 0.91A 4u9uB-5di0A:
undetectable		 4u9uB-5di0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		3 / 4 ARG A 269
GLY A 268
GLU A 168
 None
PEG  A 411 (-3.8A)
None
 0.61A 4z2dB-5di0A:
undetectable
4z2dC-5di0A:
undetectable		 4z2dB-5di0A:
20.40
4z2dC-5di0A:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 5di0 NATTERIN-LIKE
PROTEIN
(Danio
rerio) 		4 / 5 ILE A   9
LEU A  29
GLY A 125
PHE A 139
 PEG  A 408 (-4.3A)
None
None
None
 0.78A 5kmdC-5di0A:
undetectable
5kmdD-5di0A:
undetectable		 5kmdC-5di0A:
24.66
5kmdD-5di0A:
24.66