SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dih'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 5dih MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 10 GLU A  72
ALA A  40
LEU A  25
GLU A  93
LEU A  61
 None
 1.21A 1ie4A-5dihA:
undetectable
1ie4C-5dihA:
undetectable		 1ie4A-5dihA:
22.33
1ie4C-5dihA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 5dih MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 10 LEU A  25
GLU A  93
LEU A  61
GLU A  72
ALA A  40
 None
 1.20A 1ie4A-5dihA:
undetectable
1ie4C-5dihA:
undetectable		 1ie4A-5dihA:
22.33
1ie4C-5dihA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 5dih MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		3 / 3 ASP A 134
PHE A 162
VAL A 178
 None
 0.77A 1kijB-5dihA:
undetectable		 1kijB-5dihA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 5dih MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		3 / 3 PRO A   5
ASP A   9
ASP A 106
 None
 0.67A 1sqfA-5dihA:
undetectable		 1sqfA-5dihA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 5dih MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		4 / 4 ASP A  90
LEU A  27
LEU A  25
LEU A  89
 None
 1.39A 1u18A-5dihA:
undetectable		 1u18A-5dihA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 5dih MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		4 / 6 ALA A 139
ILE A 122
VAL A 124
PHE A 162
 None
 0.88A 2cizA-5dihA:
undetectable		 2cizA-5dihA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 5dih MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		3 / 3 GLN A 100
THR A 163
TRP A 114
 None
 1.18A 2rctA-5dihA:
undetectable		 2rctA-5dihA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 5dih MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		3 / 3 ASP A 112
ARG A 202
ARG A 103
 None
 0.99A 3k37A-5dihA:
undetectable		 3k37A-5dihA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5dih MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 12 GLU A  26
LEU A 140
ALA A 132
LEU A 147
LEU A 105
 None
 1.19A 6ew0F-5dihA:
undetectable		 6ew0F-5dihA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 5dih MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 12 GLU A  26
LEU A 140
ALA A 132
LEU A 147
LEU A 105
 None
 1.19A 6ew0G-5dihA:
undetectable		 6ew0G-5dihA:
14.63