SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dil'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 5dil NON-STRUCTURAL
PROTEIN 1
(Influenza
B
virus) 		5 / 10 LEU A 209
LEU A 243
SER A 184
LEU A 185
ARG A 186
 None
 1.18A 2ceoB-5dilA:
undetectable		 2ceoB-5dilA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 5dil NON-STRUCTURAL
PROTEIN 1
(Influenza
B
virus) 		5 / 12 LEU A 209
LEU A 222
ALA A 224
PHE A 171
THR A 192
 None
 1.33A 3gwuA-5dilA:
undetectable		 3gwuA-5dilA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5dil NON-STRUCTURAL
PROTEIN 1
(Influenza
B
virus) 		4 / 5 ASN A 152
ALA A 155
ARG A 208
LYS A 221
 None
None
None
IOD  A 305 (-3.7A)
 1.45A 3kp2B-5dilA:
undetectable		 3kp2B-5dilA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 5dil NON-STRUCTURAL
PROTEIN 1
(Influenza
B
virus) 		5 / 12 ILE A 239
ILE A 255
ALA A 257
LEU A 173
LEU A 265
 None
 1.13A 3vw1B-5dilA:
undetectable		 3vw1B-5dilA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 5dil NON-STRUCTURAL
PROTEIN 1
(Influenza
B
virus) 		5 / 12 ILE A 239
ARG A 246
LEU A 243
LEU A 274
LEU A 265
 None
 1.32A 4qynB-5dilA:
undetectable		 4qynB-5dilA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 5dil NON-STRUCTURAL
PROTEIN 1
(Influenza
B
virus) 		5 / 12 VAL A 187
LEU A 240
LEU A 173
ILE A 175
ALA A 220
 None
 1.49A 5xprA-5dilA:
undetectable		 5xprA-5dilA:
16.31