SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5diz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		3 / 3 TRP A 425
TYR A 424
LEU A 305
 None
 0.97A 1kxhA-5dizA:
undetectable		 1kxhA-5dizA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		4 / 5 GLU A 180
ARG A 117
LEU A 146
LEU A 154
 None
 1.21A 1n13B-5dizA:
undetectable
1n13C-5dizA:
undetectable		 1n13B-5dizA:
12.26
1n13C-5dizA:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		3 / 3 GLU A 405
ASN A 409
TRP A 380
 None
 1.24A 1r15C-5dizA:
undetectable		 1r15C-5dizA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		3 / 3 GLU A 405
ASN A 409
TRP A 380
 None
 1.26A 1r15D-5dizA:
undetectable		 1r15D-5dizA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		3 / 3 GLU A 405
ASN A 409
TRP A 380
 None
 1.27A 1r15E-5dizA:
undetectable		 1r15E-5dizA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		3 / 3 GLU A 405
ASN A 409
TRP A 380
 None
 1.25A 1r15F-5dizA:
undetectable		 1r15F-5dizA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		4 / 7 SER A 114
SER A 111
ASN A 108
GLN A  66
 None
 1.14A 2cmlA-5dizA:
undetectable		 2cmlA-5dizA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		4 / 8 SER A 114
SER A 111
ASN A 108
GLN A  66
 None
 1.02A 2cmlB-5dizA:
undetectable		 2cmlB-5dizA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		4 / 8 SER A 114
SER A 111
ASN A 108
GLN A  66
 None
 1.13A 2cmlD-5dizA:
undetectable		 2cmlD-5dizA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		4 / 7 ALA A 429
LEU A 426
PHE A 454
PHE A 455
 None
 0.97A 2vcvL-5dizA:
2.6		 2vcvL-5dizA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		3 / 3 LEU A 308
GLU A 448
ILE A 446
 None
 0.55A 3czhA-5dizA:
undetectable		 3czhA-5dizA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA213_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		5 / 10 PHE A 226
PHE A 495
GLU A 487
VAL A 234
TYR A 201
 None
 1.36A 3r6wA-5dizA:
undetectable
3r6wB-5dizA:
undetectable		 3r6wA-5dizA:
18.34
3r6wB-5dizA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		4 / 6 LEU A  34
ALA A  49
LEU A  75
THR A  71
 None
 1.10A 3rozA-5dizA:
undetectable		 3rozA-5dizA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		3 / 3 HIS A 399
SER A 366
GLU A 365
 None
 0.77A 3s8pA-5dizA:
undetectable		 3s8pA-5dizA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		3 / 3 PHE A  35
LYS A  42
SER A  41
 None
 1.01A 3tyeB-5dizA:
undetectable		 3tyeB-5dizA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		3 / 3 PHE A  35
LYS A  42
SER A  43
 None
 1.37A 3tyeB-5dizA:
undetectable		 3tyeB-5dizA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		3 / 3 GLN A 329
ASP A 303
GLN A 299
 None
 0.77A 4aztA-5dizA:
undetectable		 4aztA-5dizA:
23.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		4 / 6 ALA A 345
ASN A 346
LEU A 349
ASP A 440
 None
 0.35A 4g24A-5dizA:
34.8		 4g24A-5dizA:
46.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		4 / 5 GLU A 109
SER A 111
ARG A 145
SER A 114
 None
 1.26A 4k17B-5dizA:
undetectable		 4k17B-5dizA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		5 / 12 THR A 453
ILE A 485
GLY A 212
PHE A 495
VAL A 484
 None
 1.14A 4rvgA-5dizA:
undetectable		 4rvgA-5dizA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		4 / 6 LEU A  33
CYH A  40
HIS A  68
LEU A  72
 None
 1.30A 5hrqD-5dizA:
undetectable
5hrqG-5dizA:
undetectable
5hrqH-5dizA:
undetectable		 5hrqD-5dizA:
4.75
5hrqG-5dizA:
5.36
5hrqH-5dizA:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		4 / 6 GLU A 109
ARG A 145
LEU A 146
ARG A 147
 None
 0.92A 5l6eA-5dizA:
undetectable
5l6eB-5dizA:
undetectable		 5l6eA-5dizA:
17.68
5l6eB-5dizA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5diz PROTEINACEOUS RNASE
P 2
(Arabidopsis
thaliana) 		5 / 10 GLY A 123
GLY A 125
VAL A 115
LEU A 118
ARG A 117
 None
 1.07A 5o96E-5dizA:
undetectable
5o96F-5dizA:
undetectable		 5o96E-5dizA:
17.88
5o96F-5dizA:
17.88