SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		3 / 3 TRP A 114
ALA A 112
VAL A  87
 None
 0.94A 1av2C-5djiA:
undetectable
1av2D-5djiA:
undetectable		 1av2C-5djiA:
4.17
1av2D-5djiA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 10 LEU A 247
ALA A 201
ASP A 200
ILE A 179
PRO A 167
 None
 0.95A 1d4sA-5djiA:
undetectable		 1d4sA-5djiA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ND4_A_KANA1300_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 10 ASP A  50
GLU A  47
ASP A 212
ASP A  91
GLU A  74
 PO4  A 304 ( 3.9A)
None
MG  A 302 ( 2.7A)
MG  A 301 (-2.5A)
None
 1.41A 1nd4A-5djiA:
undetectable		 1nd4A-5djiA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 8 GLY A  46
GLU A  47
ALA A  48
ILE A  37
 None
 0.74A 2dtjA-5djiA:
undetectable
2dtjB-5djiA:
undetectable		 2dtjA-5djiA:
21.12
2dtjB-5djiA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 112
VAL A  87
TRP A 114
 None
 0.95A 2izqA-5djiA:
undetectable
2izqB-5djiA:
undetectable		 2izqA-5djiA:
4.17
2izqB-5djiA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 247
ALA A 201
ASP A 200
ILE A 179
PRO A 167
 None
 1.00A 2o4lA-5djiA:
undetectable		 2o4lA-5djiA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 247
ALA A 201
ASP A 200
ILE A 179
PRO A 167
 None
 1.04A 2o4pA-5djiA:
undetectable		 2o4pA-5djiA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 9 LEU A 248
VAL A 254
ALA A 201
MET A 225
LEU A 235
 None
 1.41A 2qo5A-5djiA:
0.6		 2qo5A-5djiA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		3 / 3 TRP A 114
ALA A 112
VAL A  87
 None
 0.85A 3l8lA-5djiA:
undetectable
3l8lB-5djiA:
undetectable		 3l8lA-5djiA:
4.17
3l8lB-5djiA:
3.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 248
ILE A 262
GLY A 260
ALA A 261
LEU A 177
 None
 1.18A 3n8yA-5djiA:
undetectable		 3n8yA-5djiA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 247
ALA A 201
ASP A 200
ILE A 179
PRO A 167
 None
 1.06A 3spkA-5djiA:
undetectable		 3spkA-5djiA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 247
ALA A 201
ASP A 200
ILE A 179
PRO A 167
 None
 0.99A 3spkB-5djiA:
undetectable		 3spkB-5djiA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 9 ASP A 212
ASP A  91
GLY A 185
ILE A 184
VAL A 129
 MG  A 302 ( 2.7A)
MG  A 301 (-2.5A)
AMP  A 303 (-3.6A)
None
None
 1.06A 3u7sB-5djiA:
undetectable		 3u7sB-5djiA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_C_SVRC516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 9 PRO A 167
GLY A 206
ALA A 205
ARG A 229
LEU A 230
 None
AMP  A 303 (-4.3A)
None
None
None
 1.48A 3ur0C-5djiA:
undetectable		 3ur0C-5djiA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 5 SER A 100
GLU A  98
THR A 101
ASP A 106
 None
AMP  A 303 ( 4.1A)
None
None
 1.41A 3zs3A-5djiA:
undetectable		 3zs3A-5djiA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 12 MET A 249
GLY A 185
SER A 186
GLN A 208
ILE A 184
 None
AMP  A 303 (-3.6A)
None
AMP  A 303 (-4.1A)
None
 1.42A 4djfA-5djiA:
undetectable		 4djfA-5djiA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 247
ALA A 201
ASP A 200
ILE A 179
PRO A 167
 None
 1.05A 4njuC-5djiA:
undetectable		 4njuC-5djiA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		3 / 3 THR A  14
ASP A  15
ALA A  16
 None
 0.00A 5g5gB-5djiA:
undetectable		 5g5gB-5djiA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 10 ILE A 111
ASN A 238
LEU A  61
ALA A  69
GLU A 123
 None
 1.19A 5y7pG-5djiA:
undetectable		 5y7pG-5djiA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 8 ASP A  94
HIS A 110
GLU A  74
ASP A  50
 MG  A 302 (-3.1A)
None
None
PO4  A 304 ( 3.9A)
 1.21A 6mn4B-5djiA:
undetectable		 6mn4B-5djiA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5dji 3'-PHOSPHOADENOSINE
5'-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 8 ASP A 212
HIS A 110
GLU A  74
ASP A  50
 MG  A 302 ( 2.7A)
None
None
PO4  A 304 ( 3.9A)
 1.26A 6mn4C-5djiA:
undetectable		 6mn4C-5djiA:
23.51