SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 5dju NPH1-2
ENGINEERED PROTEIN,
ZDK3 AFFIBODY
(Avena
sativa;
Staphylococcus
aureus) 		5 / 9 ILE A 417
ILE A 510
PHE B  28
ALA A 542
LEU A 408
 None
 1.08A 2m9qA-5djuA:
undetectable		 2m9qA-5djuA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5dju NPH1-2
(Avena
sativa) 		5 / 11 ASP A 471
ASN A 472
VAL A 476
PHE A 509
ILE A 466
 None
None
None
None
FMN  A 601 ( 4.4A)
 1.18A 3n23A-5djuA:
undetectable		 3n23A-5djuA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5dju NPH1-2
(Avena
sativa) 		5 / 11 ASP A 471
VAL A 476
PHE A 509
ILE A 466
ARG A 421
 None
None
None
FMN  A 601 ( 4.4A)
None
 1.13A 3n23A-5djuA:
undetectable		 3n23A-5djuA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 5dju NPH1-2
ENGINEERED PROTEIN,
ZDK3 AFFIBODY
(Avena
sativa;
Staphylococcus
aureus) 		4 / 7 ALA A 542
LEU A 408
TYR B  17
LEU A 546
 None
 0.95A 4iomA-5djuA:
undetectable		 4iomA-5djuA:
12.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 5dju NPH1-2
(Avena
sativa) 		8 / 12 VAL A 416
ASN A 425
ASN A 449
ARG A 451
GLN A 454
ASN A 482
ASN A 492
GLN A 513
 None
FMN  A 601 ( 3.9A)
FMN  A 601 ( 3.1A)
FMN  A 601 ( 3.8A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.9A)
FMN  A 601 (-3.8A)
 0.47A 4kukA-5djuA:
17.3		 4kukA-5djuA:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 5dju NPH1-2
(Avena
sativa) 		6 / 9 LEU A 453
VAL A 463
ILE A 466
ARG A 467
PHE A 509
GLY A 511
 FMN  A 601 (-4.0A)
FMN  A 601 (-4.6A)
FMN  A 601 ( 4.4A)
None
None
FMN  A 601 (-3.8A)
 0.82A 4kukA-5djuA:
17.3		 4kukA-5djuA:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 5dju NPH1-2
(Avena
sativa) 		8 / 12 VAL A 416
ASN A 425
ASN A 449
ARG A 451
GLN A 454
ASN A 482
ASN A 492
GLN A 513
 None
FMN  A 601 ( 3.9A)
FMN  A 601 ( 3.1A)
FMN  A 601 ( 3.8A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.9A)
FMN  A 601 (-3.8A)
 0.59A 4kuoA-5djuA:
17.3		 4kuoA-5djuA:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5dju NPH1-2
(Avena
sativa) 		7 / 12 ARG A 451
GLN A 454
ILE A 470
ASN A 482
ASN A 492
GLY A 511
GLN A 513
 FMN  A 601 ( 3.8A)
FMN  A 601 (-3.1A)
CL  A 603 (-4.4A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.9A)
FMN  A 601 (-3.8A)
FMN  A 601 (-3.8A)
 0.58A 4r38A-5djuA:
17.6		 4r38A-5djuA:
32.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5dju NPH1-2
(Avena
sativa) 		5 / 12 GLN A 513
ALA A 430
ASN A 492
ASN A 482
GLN A 454
 FMN  A 601 (-3.8A)
None
FMN  A 601 (-3.9A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.1A)
 1.21A 4r38A-5djuA:
17.6		 4r38A-5djuA:
32.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5dju NPH1-2
(Avena
sativa) 		8 / 12 ASN A 449
ARG A 451
GLN A 454
ILE A 470
ASN A 482
ASN A 492
GLY A 511
GLN A 513
 FMN  A 601 ( 3.1A)
FMN  A 601 ( 3.8A)
FMN  A 601 (-3.1A)
CL  A 603 (-4.4A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.9A)
FMN  A 601 (-3.8A)
FMN  A 601 (-3.8A)
 0.62A 4r38B-5djuA:
17.2		 4r38B-5djuA:
32.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5dju NPH1-2
(Avena
sativa) 		7 / 12 ARG A 451
GLN A 454
ILE A 470
ASN A 482
ASN A 492
GLY A 511
GLN A 513
 FMN  A 601 ( 3.8A)
FMN  A 601 (-3.1A)
CL  A 603 (-4.4A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.9A)
FMN  A 601 (-3.8A)
FMN  A 601 (-3.8A)
 0.58A 4r38C-5djuA:
17.4		 4r38C-5djuA:
32.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5dju NPH1-2
(Avena
sativa) 		7 / 12 ARG A 451
GLN A 454
ILE A 470
ASN A 482
ASN A 492
GLY A 511
GLN A 513
 FMN  A 601 ( 3.8A)
FMN  A 601 (-3.1A)
CL  A 603 (-4.4A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.9A)
FMN  A 601 (-3.8A)
FMN  A 601 (-3.8A)
 0.59A 4r38D-5djuA:
17.4		 4r38D-5djuA:
32.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5dju NPH1-2
(Avena
sativa) 		5 / 12 GLN A 513
ALA A 430
ASN A 492
ASN A 482
GLN A 454
 FMN  A 601 (-3.8A)
None
FMN  A 601 (-3.9A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.1A)
 1.23A 4r38D-5djuA:
17.4		 4r38D-5djuA:
32.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5dju NPH1-2
(Avena
sativa) 		6 / 12 ARG A 451
GLN A 454
ILE A 470
ASN A 482
ASN A 492
GLN A 513
 FMN  A 601 ( 3.8A)
FMN  A 601 (-3.1A)
CL  A 603 (-4.4A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.9A)
FMN  A 601 (-3.8A)
 0.51A 4r3aA-5djuA:
18.2		 4r3aA-5djuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5dju NPH1-2
(Avena
sativa) 		5 / 10 ASN A 449
LEU A 453
GLN A 454
VAL A 463
PHE A 509
 FMN  A 601 ( 3.1A)
FMN  A 601 (-4.0A)
FMN  A 601 (-3.1A)
FMN  A 601 (-4.6A)
None
 0.63A 4r3aB-5djuA:
17.9		 4r3aB-5djuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5dju NPH1-2
(Avena
sativa) 		6 / 12 ARG A 451
ILE A 470
ASN A 482
ASN A 492
GLY A 511
GLN A 513
 FMN  A 601 ( 3.8A)
CL  A 603 (-4.4A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.9A)
FMN  A 601 (-3.8A)
FMN  A 601 (-3.8A)
 0.38A 4r3aB-5djuA:
17.9		 4r3aB-5djuA:
21.18