SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5djw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 11 ASN A 466
SER A 404
GLY A 432
PHE A 443
GLY A 433
 None
 1.31A 1ho5A-5djwA:
undetectable		 1ho5A-5djwA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 10 ASN A 466
SER A 404
GLY A 432
PHE A 443
GLY A 433
 None
 1.36A 1ho5B-5djwA:
undetectable		 1ho5B-5djwA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 176
SER A 591
ASN A 590
ASP A 617
 None
 1.13A 1ig3A-5djwA:
undetectable
1ig3B-5djwA:
undetectable		 1ig3A-5djwA:
16.50
1ig3B-5djwA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 7 ASP A 617
LEU A 176
SER A 591
ASN A 590
 None
 1.05A 1ig3A-5djwA:
undetectable
1ig3B-5djwA:
undetectable		 1ig3A-5djwA:
16.50
1ig3B-5djwA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 568
ALA A 540
GLY A 448
TYR A 566
LEU A 442
 None
 1.11A 1qabF-5djwA:
undetectable		 1qabF-5djwA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 490
ILE A 583
ILE A 489
THR A 596
 None
 0.95A 1sbrA-5djwA:
undetectable		 1sbrA-5djwA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 9 GLY A 177
ALA A 175
LEU A 176
PHE A 381
LEU A 498
 None
 1.29A 1y7iA-5djwA:
undetectable		 1y7iA-5djwA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A  67
GLY A  66
SER A 422
LEU A  74
SER A  73
 None
 0.98A 1ya4A-5djwA:
undetectable		 1ya4A-5djwA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_A_CHDA1_0
(LIVER
CARBOXYLESTERASE 1)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 5 TRP A 613
GLY A 649
LYS A 647
LEU A 629
 None
 1.49A 2dqyA-5djwA:
undetectable		 2dqyA-5djwA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 416
THR A 384
GLN A 101
 None
 0.74A 2fk8A-5djwA:
undetectable		 2fk8A-5djwA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 GLY A 370
ARG A 304
TYR A 307
 None
 0.83A 2opxA-5djwA:
undetectable		 2opxA-5djwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
ILE A 212
TRP A 285
ASP A 321
ARG A 385
 None
 1.04A 2qmjA-5djwA:
36.2		 2qmjA-5djwA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 211
TRP A 285
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.31A 2qmjA-5djwA:
36.2		 2qmjA-5djwA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 414
VAL A 413
GLU A 525
ALA A 528
 None
 1.00A 2v32A-5djwA:
undetectable
2v32B-5djwA:
undetectable		 2v32A-5djwA:
16.38
2v32B-5djwA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 414
VAL A 413
GLU A 525
ALA A 528
 None
 0.96A 2v32A-5djwA:
undetectable
2v32B-5djwA:
undetectable		 2v32A-5djwA:
16.38
2v32B-5djwA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 620
HIS A 499
THR A 648
LEU A 628
 None
 1.14A 3arrA-5djwA:
3.1		 3arrA-5djwA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 533
ARG A 573
ARG A 159
 None
 0.74A 3k37A-5djwA:
undetectable		 3k37A-5djwA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 319
ASP A 321
ASP A 401
PHE A 434
 None
 1.44A 3l4wA-5djwA:
36.1		 3l4wA-5djwA:
28.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 GLY A 317
TRP A 209
VAL A 207
 None
 0.72A 3n62B-5djwA:
undetectable		 3n62B-5djwA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 GLY A 317
TRP A 209
VAL A 207
 None
 0.76A 3n65B-5djwA:
undetectable		 3n65B-5djwA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 GLY A 317
TRP A 209
VAL A 207
 None
 0.72A 3n66B-5djwA:
undetectable		 3n66B-5djwA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 490
PHE A 494
ILE A 537
ILE A 482
ALA A 479
 None
 1.11A 3nxuB-5djwA:
undetectable		 3nxuB-5djwA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 204
TYR A 488
ILE A 584
ILE A 583
 None
 0.66A 3p4wC-5djwA:
undetectable		 3p4wC-5djwA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 285
ASP A 321
ASP A 401
PHE A 434
 None
 1.36A 3phaA-5djwA:
39.4		 3phaA-5djwA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 285
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.22A 3phaA-5djwA:
39.4		 3phaA-5djwA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 285
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.24A 3phaB-5djwA:
38.2		 3phaB-5djwA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 211
TRP A 285
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.38A 3phaC-5djwA:
41.4		 3phaC-5djwA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 285
ASP A 321
ASP A 401
PHE A 434
 None
 1.30A 3phaD-5djwA:
41.5		 3phaD-5djwA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 285
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.19A 3phaD-5djwA:
41.5		 3phaD-5djwA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 285
ARG A 385
ASP A 401
PHE A 434
 None
 1.44A 3topA-5djwA:
35.7		 3topA-5djwA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 285
ASP A 321
ARG A 385
PHE A 434
 None
 1.25A 3topA-5djwA:
35.7		 3topA-5djwA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 285
ARG A 385
ASP A 401
PHE A 434
 None
 1.44A 3topB-5djwA:
35.7		 3topB-5djwA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 285
ASP A 321
ARG A 385
PHE A 434
 None
 1.25A 3topB-5djwA:
35.7		 3topB-5djwA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.43A 3w37A-5djwA:
38.1		 3w37A-5djwA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 319
ASP A 321
ASP A 401
PHE A 434
 None
 1.44A 3w37A-5djwA:
38.1		 3w37A-5djwA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.43A 3welA-5djwA:
37.3		 3welA-5djwA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 319
ASP A 321
ASP A 401
PHE A 434
 None
 1.45A 3welA-5djwA:
37.3		 3welA-5djwA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  90
ASP A 211
ILE A 212
ASP A 321
ARG A 385
 None
 1.08A 3wemA-5djwA:
36.2		 3wemA-5djwA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.46A 3wemA-5djwA:
36.2		 3wemA-5djwA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.45A 3weoA-5djwA:
38.5		 3weoA-5djwA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 319
ASP A 321
ASP A 401
PHE A 434
 None
 1.46A 3weoA-5djwA:
38.5		 3weoA-5djwA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 8 GLN A 585
ILE A 203
PHE A 243
GLY A 177
 None
 0.97A 4fgjA-5djwA:
undetectable
4fgjB-5djwA:
undetectable		 4fgjA-5djwA:
15.80
4fgjB-5djwA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 216
ARG A 219
ASP A 213
 None
 0.79A 4fp9C-5djwA:
undetectable		 4fp9C-5djwA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 216
ARG A 219
ASP A 213
 None
 0.77A 4fp9F-5djwA:
undetectable		 4fp9F-5djwA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A 447
ALA A 483
TYR A 178
ALA A 456
 None
 0.81A 4g77A-5djwA:
undetectable		 4g77A-5djwA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 614
TYR A 621
TRP A 613
 None
 1.33A 4p7nA-5djwA:
11.3		 4p7nA-5djwA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 384
ASN A 387
SER A 386
 None
 0.72A 4tvtA-5djwA:
undetectable		 4tvtA-5djwA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
ILE A 212
TRP A 319
ASP A 321
ASP A 401
 None
 1.15A 5iefA-5djwA:
34.8		 5iefA-5djwA:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 319
ASP A 321
ASP A 401
PHE A 434
 None
 1.38A 5iefA-5djwA:
34.8		 5iefA-5djwA:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 7 PRO A 204
TYR A 488
ILE A 584
ILE A 583
 None
 0.68A 5murB-5djwA:
undetectable		 5murB-5djwA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 285
ASP A 321
ASP A 401
PHE A 434
 None
 1.39A 5nn6A-5djwA:
37.9		 5nn6A-5djwA:
29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 211
TRP A 319
ASP A 321
ASP A 401
PHE A 434
 None
 1.46A 5nn6A-5djwA:
37.9		 5nn6A-5djwA:
29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 211
TRP A 285
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.31A 5nn8A-5djwA:
38.7		 5nn8A-5djwA:
29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 211
TRP A 285
TRP A 319
ASP A 321
ASP A 401
PHE A 434
 None
 1.35A 5nn8A-5djwA:
38.7		 5nn8A-5djwA:
29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 413
LEU A 417
LEU A 497
PRO A 539
ALA A 528
 None
 1.30A 5og9A-5djwA:
undetectable		 5og9A-5djwA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		3 / 3 GLY A 317
TRP A 209
VAL A 207
 None
 0.77A 5vuoB-5djwA:
undetectable		 5vuoB-5djwA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 10 TRP A 319
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.16A 5x7pA-5djwA:
20.2		 5x7pA-5djwA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 436
GLY A 432
GLN A 180
TYR A 178
 None
 0.82A 6ag0A-5djwA:
10.4		 6ag0A-5djwA:
7.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 285
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.20A 6c9zA-5djwA:
36.8		 6c9zA-5djwA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 285
ASP A 321
ARG A 385
ASP A 401
PHE A 434
 None
 1.30A 6ca3B-5djwA:
36.9		 6ca3B-5djwA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 10 LEU A 164
THR A 165
GLY A 423
ILE A 158
ILE A 149
 None
 1.10A 6ebpD-5djwA:
undetectable		 6ebpD-5djwA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 164
THR A 165
GLY A 423
ILE A 158
ILE A 149
 None
 1.07A 6ebzA-5djwA:
undetectable		 6ebzA-5djwA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 164
THR A 165
GLY A 423
ILE A 158
ILE A 149
 None
 1.07A 6ebzC-5djwA:
undetectable		 6ebzC-5djwA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 164
THR A 165
GLY A 423
ILE A 158
ILE A 149
 None
 1.08A 6ebzD-5djwA:
undetectable		 6ebzD-5djwA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 5djw ALPHA-GLUCOSIDASE II
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 164
THR A 165
GLY A 423
ILE A 158
ILE A 149
 None
 1.06A 6gp2B-5djwA:
undetectable		 6gp2B-5djwA:
8.87