SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dk3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_B_ACTB1867_0 (FPRA)	5dk3	HEAVY CHAIN (Homo sapiens)	4 / 4	ALA B 40 ARG B 38 GLN B 43 GLU B 46	None	0.93A	1lqtB-5dk3B: undetectable	1lqtB-5dk3B: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_B_ACTB1424_0 (FPRA)	5dk3	HEAVY CHAIN (Homo sapiens)	4 / 4	ALA B 40 ARG B 38 GLN B 43 GLU B 46	None	0.95A	1lquB-5dk3B: undetectable	1lquB-5dk3B: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KOT_A_ANWA99_0 (PROTEIN S100-A13)	5dk3	HEAVY CHAIN (Homo sapiens)	4 / 7	VAL B 11 THR B 117 THR B 115 LYS B 208	None	1.18A	2kotA-5dk3B: undetectable	2kotA-5dk3B: 12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BRF_A_SORA2_0 (LIN-12 AND GLP-1 PHENOTYPE PROTEIN 1, ISOFORM A)	5dk3	HEAVY CHAIN (Homo sapiens)	3 / 3	LYS B 12 LYS B 19 VAL B 18	None	1.07A	3brfA-5dk3B: 2.8	3brfA-5dk3B: 21.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4M7K_H_ACTH302_0 (10H10 HEAVY CHAIN)	5dk3	HEAVY CHAIN (Homo sapiens)	4 / 5	VAL B 2 TYR B 27 ARG B 98 TYR B 109	None	0.40A	4m7kH-5dk3B: 23.4	4m7kH-5dk3B: 39.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P7N_A_GCSA701_1 (POLY-BETA-1,6-N-ACET YL-D-GLUCOSAMINE N-DEACETYLASE)	5dk3	HEAVY CHAIN (Homo sapiens)	4 / 5	TYR B 373 ASP B 280 TRP B 313 TYR B 319	None None SO4 B 504 (-4.5A) None	1.21A	4p7nA-5dk3B: 0.0	4p7nA-5dk3B: 18.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LQT_B_ACTB1867_0","FPRA","5dk3","HEAVY CHAIN","Homo sapiens",4,"ALA B  40;ARG B  38;GLN B  43;GLU B  46","None","0.93A","1lqtB-5dk3B:undetectable","1lqtB-5dk3B:21.79"],["1LQU_B_ACTB1424_0","FPRA","5dk3","HEAVY CHAIN","Homo sapiens",4,"ALA B  40;ARG B  38;GLN B  43;GLU B  46","None","0.95A","1lquB-5dk3B:undetectable","1lquB-5dk3B:21.79"],["2KOT_A_ANWA99_0","PROTEIN S100-A13","5dk3","HEAVY CHAIN","Homo sapiens",4,"VAL B  11;THR B 117;THR B 115;LYS B 208","None","1.18A","2kotA-5dk3B:undetectable","2kotA-5dk3B:12.53"],["3BRF_A_SORA2_0","LIN-12 AND GLP-1 PHENOTYPE PROTEIN 1, ISOFORM A","5dk3","HEAVY CHAIN","Homo sapiens",3,"LYS B  12;LYS B  19;VAL B  18","None","1.07A","3brfA-5dk3B:2.8","3brfA-5dk3B:21.17"],["4M7K_H_ACTH302_0","10H10 HEAVY CHAIN","5dk3","HEAVY CHAIN","Homo sapiens",4,"VAL B   2;TYR B  27;ARG B  98;TYR B 109","None","0.40A","4m7kH-5dk3B:23.4","4m7kH-5dk3B:39.77"],["4P7N_A_GCSA701_1","POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE N-DEACETYLASE","5dk3","HEAVY CHAIN","Homo sapiens",4,"TYR B 373;ASP B 280;TRP B 313;TYR B 319","None;None;SO4 B 504 (-4.5A);None","1.21A","4p7nA-5dk3B:0.0","4p7nA-5dk3B:18.66"]]