SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dkc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5dkc PROBABLE GLOBAL
TRANSCRIPTION
ACTIVATOR SNF2L2
(Homo
sapiens) 		5 / 12 LEU A1383
GLN A1386
MET A1387
ILE A1390
MET A1454
 None
 1.03A 4ltwA-5dkcA:
undetectable		 4ltwA-5dkcA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5dkc PROBABLE GLOBAL
TRANSCRIPTION
ACTIVATOR SNF2L2
(Homo
sapiens) 		4 / 7 ILE A1434
TYR A1443
ASN A1459
ARG A1437
 None
 1.38A 4o7gA-5dkcA:
undetectable
4o7gB-5dkcA:
undetectable		 4o7gA-5dkcA:
16.45
4o7gB-5dkcA:
16.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5dkc PROBABLE GLOBAL
TRANSCRIPTION
ACTIVATOR SNF2L2
(Homo
sapiens) 		5 / 5 LEU A1412
TYR A1421
ALA A1460
ASN A1464
ILE A1470
 5BW  A1502 (-4.2A)
5BW  A1502 (-4.5A)
5BW  A1502 (-3.5A)
5BW  A1502 (-3.2A)
5BW  A1502 (-4.9A)
 0.41A 4y03B-5dkcA:
20.6		 4y03B-5dkcA:
36.92