SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dkd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5dkd TRANSCRIPTION
ACTIVATOR BRG1
(Homo
sapiens) 		5 / 11 PHE A1507
ILE A1486
ALA A1536
ASN A1535
VAL A1469
 None
None
5BW  A1605 (-3.4A)
None
None
 1.17A 2gl0B-5dkdA:
undetectable
2gl0C-5dkdA:
undetectable		 2gl0B-5dkdA:
23.21
2gl0C-5dkdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5dkd TRANSCRIPTION
ACTIVATOR BRG1
(Homo
sapiens) 		4 / 6 GLU A1548
ASP A1549
ASP A1474
ARG A1479
 None
 1.07A 4kcnA-5dkdA:
undetectable		 4kcnA-5dkdA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5dkd TRANSCRIPTION
ACTIVATOR BRG1
(Homo
sapiens) 		4 / 6 GLU A1548
ASP A1549
ASP A1474
ARG A1479
 None
 1.13A 4kcnB-5dkdA:
undetectable		 4kcnB-5dkdA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5dkd TRANSCRIPTION
ACTIVATOR BRG1
(Homo
sapiens) 		4 / 7 ILE A1510
TYR A1519
ASN A1535
ARG A1513
 None
None
None
EDO  A1602 (-3.9A)
 1.31A 4o7gA-5dkdA:
undetectable
4o7gB-5dkdA:
undetectable		 4o7gA-5dkdA:
20.00
4o7gB-5dkdA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5dkd TRANSCRIPTION
ACTIVATOR BRG1
(Homo
sapiens) 		5 / 5 LEU A1488
TYR A1497
ALA A1536
ASN A1540
ILE A1546
 5BW  A1605 (-4.0A)
5BW  A1605 (-4.6A)
5BW  A1605 (-3.4A)
5BW  A1605 (-3.3A)
None
 0.46A 4y03B-5dkdA:
19.6		 4y03B-5dkdA:
39.06