SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dkv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		4 / 8 ASP A 121
TYR A 129
TYR A 142
THR A 179
 T6T  A 401 (-2.0A)
None
None
T6T  A 401 (-3.0A)
 1.26A 1ceaA-5dkvA:
undetectable
1ceaB-5dkvA:
undetectable		 1ceaA-5dkvA:
13.45
1ceaB-5dkvA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		4 / 6 LYS A 108
LYS A 109
ASP A 112
ALA A 113
 None
 0.35A 1iwhA-5dkvA:
undetectable		 1iwhA-5dkvA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 12 ALA A 144
PRO A  97
GLY A  40
LEU A  41
ASP A 121
 None
None
None
None
T6T  A 401 (-2.0A)
 1.36A 2nv4B-5dkvA:
undetectable		 2nv4B-5dkvA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 12 GLY A 231
SER A 236
ALA A 212
LEU A 216
VAL A 168
 None
 1.15A 2yvlC-5dkvA:
2.9		 2yvlC-5dkvA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		3 / 3 ASN A 172
MET A 191
PHE A 230
 None
 0.80A 3g4lD-5dkvA:
undetectable		 3g4lD-5dkvA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 12 PHE A  73
GLY A  40
ALA A  96
THR A 119
ILE A 124
 T6T  A 401 ( 4.5A)
None
None
None
None
 1.26A 3ld6A-5dkvA:
undetectable		 3ld6A-5dkvA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 12 PHE A  73
GLY A  40
ALA A  96
THR A 119
ILE A 124
 T6T  A 401 ( 4.5A)
None
None
None
None
 1.25A 3ld6B-5dkvA:
undetectable		 3ld6B-5dkvA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 12 GLY A 231
GLY A 237
LEU A 238
ASN A 205
ALA A 154
 None
 1.26A 3vywB-5dkvA:
undetectable		 3vywB-5dkvA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 12 GLY A 231
GLY A 237
LEU A 238
ASN A 205
ALA A 154
 None
 1.22A 3vywD-5dkvA:
3.1		 3vywD-5dkvA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 11 GLY A 288
ALA A 292
ILE A  35
PRO A  90
ILE A  66
 None
 1.07A 4dt8A-5dkvA:
undetectable		 4dt8A-5dkvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 10 GLY A 288
ALA A 292
ILE A  35
PRO A  90
ILE A  66
 None
 1.01A 4dt8B-5dkvA:
undetectable		 4dt8B-5dkvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 9 TYR A 129
ASP A 128
ALA A 144
GLY A 125
PHE A 123
 None
 1.36A 4mmfA-5dkvA:
undetectable		 4mmfA-5dkvA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		4 / 5 THR A 179
THR A 122
ASP A 121
TYR A  47
 T6T  A 401 (-3.0A)
T6T  A 401 ( 4.7A)
T6T  A 401 (-2.0A)
T6T  A 401 (-4.0A)
 1.18A 4oltB-5dkvA:
undetectable		 4oltB-5dkvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 12 PHE A 235
GLY A 239
ALA A 213
SER A 214
ASP A 208
 T6T  A 401 ( 4.5A)
None
None
None
None
 1.21A 4rtpA-5dkvA:
undetectable		 4rtpA-5dkvA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		4 / 5 TYR A 142
PHE A 138
LEU A 103
PRO A 139
 None
 1.40A 5csyB-5dkvA:
undetectable		 5csyB-5dkvA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		4 / 8 ALA A 321
ARG A 324
HIS A 280
THR A 310
 None
 1.22A 5db5A-5dkvA:
4.0
5db5B-5dkvA:
3.7		 5db5A-5dkvA:
22.58
5db5B-5dkvA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 12 ASP A 181
ASP A  72
THR A  77
GLY A  40
THR A  42
 None
 1.22A 5hfjH-5dkvA:
3.4		 5hfjH-5dkvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		4 / 7 THR A 179
ASP A 121
TYR A  47
GLY A  40
 T6T  A 401 (-3.0A)
T6T  A 401 (-2.0A)
T6T  A 401 (-4.0A)
None
 1.01A 5hwaA-5dkvA:
undetectable		 5hwaA-5dkvA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 9 ALA A 257
ALA A 260
ALA A 276
GLY A 239
ALA A 241
 None
 1.05A 5l5zK-5dkvA:
undetectable
5l5zL-5dkvA:
undetectable		 5l5zK-5dkvA:
24.06
5l5zL-5dkvA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		5 / 9 ALA A 257
ALA A 260
ALA A 276
GLY A 239
ALA A 241
 None
 1.04A 5l5zY-5dkvA:
undetectable
5l5zZ-5dkvA:
undetectable		 5l5zY-5dkvA:
24.06
5l5zZ-5dkvA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		4 / 7 THR A 179
PHE A  46
MET A  50
THR A 307
 T6T  A 401 (-3.0A)
T6T  A 401 (-3.2A)
None
None
 1.42A 5u6mA-5dkvA:
5.3		 5u6mA-5dkvA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 5dkv ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		4 / 7 THR A 179
PHE A  46
MET A  50
THR A 307
 T6T  A 401 (-3.0A)
T6T  A 401 (-3.2A)
None
None
 1.48A 5u6mB-5dkvA:
5.6		 5u6mB-5dkvA:
20.65