SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dl2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 5dl2 REGULATOR OF
PROTEASE B (ROPB)
(Streptococcus
pyogenes) 		3 / 3 CYH A 228
PHE A 231
PHE A 232
 None
 0.52A 3cr5X-5dl2A:
undetectable		 3cr5X-5dl2A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5dl2 REGULATOR OF
PROTEASE B (ROPB)
(Streptococcus
pyogenes) 		4 / 6 VAL A 250
LEU A 272
ILE A 252
CYH A 249
 None
 0.86A 4asdA-5dl2A:
undetectable		 4asdA-5dl2A:
22.32