SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dl6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 5 GLU A 345
TYR A 371
SER A 305
ASP A 290
 None
 1.44A 1vidA-5dl6A:
undetectable		 1vidA-5dl6A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		5 / 11 PHE A 296
LEU A 297
HIS A 252
THR A 326
GLU A 345
 None
 1.32A 2dttD-5dl6A:
undetectable
2dttE-5dl6A:
undetectable		 2dttD-5dl6A:
14.63
2dttE-5dl6A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 7 SER A 305
LEU A 287
PHE A 296
THR A 291
 None
 1.07A 2f78A-5dl6A:
undetectable		 2f78A-5dl6A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 7 SER A 305
LEU A 287
PHE A 296
THR A 291
 None
 1.04A 2f78B-5dl6A:
undetectable		 2f78B-5dl6A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		3 / 3 ARG A  20
ARG A 124
ARG A 388
 None
 1.14A 2jb7A-5dl6A:
undetectable
2jb7B-5dl6A:
undetectable
2jb7C-5dl6A:
undetectable		 2jb7A-5dl6A:
16.02
2jb7B-5dl6A:
16.02
2jb7C-5dl6A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		3 / 3 ARG A 124
ARG A 388
ARG A  20
 None
 1.15A 2jb7A-5dl6A:
undetectable
2jb7B-5dl6A:
undetectable
2jb7C-5dl6A:
undetectable		 2jb7A-5dl6A:
16.02
2jb7B-5dl6A:
16.02
2jb7C-5dl6A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		3 / 3 ARG A 388
ARG A  20
ARG A 124
 None
 1.18A 2jb7A-5dl6A:
undetectable
2jb7B-5dl6A:
undetectable
2jb7C-5dl6A:
undetectable		 2jb7A-5dl6A:
16.02
2jb7B-5dl6A:
16.02
2jb7C-5dl6A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		3 / 3 SER A 227
GLU A 309
ASP A 347
 None
 0.64A 2zulA-5dl6A:
undetectable		 2zulA-5dl6A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 6 GLU A 345
TYR A 371
SER A 305
ASP A 290
 None
 1.39A 2zvjA-5dl6A:
undetectable		 2zvjA-5dl6A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		3 / 3 SER A 227
GLU A 309
ASP A 347
 None
 0.61A 3dmhA-5dl6A:
undetectable		 3dmhA-5dl6A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 7 LEU A 111
ASP A  56
SER A 134
THR A 136
 None
 1.09A 3dzgB-5dl6A:
undetectable		 3dzgB-5dl6A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 7 TYR A 149
TYR A 182
TYR A 200
TYR A 207
 None
 1.12A 3ku9B-5dl6A:
undetectable		 3ku9B-5dl6A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		3 / 3 ILE A 381
VAL A 169
ARG A 172
 None
 0.70A 3p73A-5dl6A:
undetectable		 3p73A-5dl6A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 8 ARG A 124
LEU A 125
THR A  74
TYR A  17
 None
 1.21A 3wipF-5dl6A:
undetectable
3wipJ-5dl6A:
undetectable		 3wipF-5dl6A:
19.63
3wipJ-5dl6A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 7 GLY A 294
ILE A 381
ASN A 298
GLU A 295
 None
 1.12A 4g0vA-5dl6A:
undetectable		 4g0vA-5dl6A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 6 ARG A 365
GLU A 309
ARG A 324
ASP A 347
 None
 1.12A 4kcnA-5dl6A:
undetectable		 4kcnA-5dl6A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 6 GLU A 309
ARG A 324
ASP A 349
ASP A 347
 None
 1.28A 4kcnA-5dl6A:
undetectable		 4kcnA-5dl6A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 6 ARG A 365
GLU A 309
ARG A 324
ASP A 347
 None
 1.14A 4kcnB-5dl6A:
undetectable		 4kcnB-5dl6A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 6 GLU A 309
ARG A 324
ASP A 349
ASP A 347
 None
 1.29A 4kcnB-5dl6A:
undetectable		 4kcnB-5dl6A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		5 / 9 THR A 291
LEU A 288
LEU A 250
GLN A 270
PHE A 269
 None
 1.42A 4ltwA-5dl6A:
undetectable		 4ltwA-5dl6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 8 GLY A  75
THR A  35
ASN A  76
PHE A  16
 None
 1.10A 4m5mA-5dl6A:
undetectable		 4m5mA-5dl6A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 6 GLU A 295
ASP A 290
GLU A 386
ARG A 156
 None
 1.29A 4ntxA-5dl6A:
undetectable
4ntxC-5dl6A:
undetectable		 4ntxA-5dl6A:
22.87
4ntxC-5dl6A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		5 / 12 ASN A 373
ALA A 333
GLY A 338
GLY A 337
ASN A 170
 None
 1.03A 4obwB-5dl6A:
undetectable		 4obwB-5dl6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		5 / 12 ARG A 388
ALA A 123
ARG A 156
GLY A 283
GLU A 345
 None
 1.19A 4r29B-5dl6A:
undetectable		 4r29B-5dl6A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		5 / 11 VAL A 246
ASP A 237
GLY A 168
PHE A 173
GLY A 244
 None
 1.25A 4xp4A-5dl6A:
undetectable		 4xp4A-5dl6A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		5 / 11 VAL A 246
ASP A 237
TYR A 207
GLY A 168
PHE A 173
 None
 1.25A 4xp4A-5dl6A:
undetectable		 4xp4A-5dl6A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)
(Acinetobacter
baumannii) 		4 / 7 ALA A 243
GLY A 244
LEU A 245
GLY A 171
 None
 0.76A 6nm4A-5dl6A:
undetectable		 6nm4A-5dl6A:
20.20