SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dl7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILQ_C_ACAC7_1
(INTERLEUKIN-8
PRECURSOR
INTERLEUKIN-8
RECEPTOR A)		 5dl7 PORIN
(Acinetobacter
baumannii) 		4 / 6 HIS A 251
PHE A 234
ASP A 230
PRO A 287
 None
 1.17A 1ilqA-5dl7A:
undetectable
1ilqC-5dl7A:
undetectable		 1ilqA-5dl7A:
11.32
1ilqC-5dl7A:
3.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 5dl7 PORIN
(Acinetobacter
baumannii) 		3 / 3 SER A 298
THR A 118
GLN A 210
 None
 0.80A 2fk8A-5dl7A:
undetectable		 2fk8A-5dl7A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5dl7 PORIN
(Acinetobacter
baumannii) 		4 / 6 LEU A 281
ASN A 249
ILE A 207
PHE A 183
 None
 1.20A 2jn3A-5dl7A:
1.8		 2jn3A-5dl7A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5dl7 PORIN
(Acinetobacter
baumannii) 		4 / 8 ARG A 250
ASP A 339
LEU A 341
ASP A 345
 C8E  A 511 (-2.9A)
None
None
None
 0.80A 2zw9A-5dl7A:
undetectable		 2zw9A-5dl7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_0
(N,N-DIMETHYLTRANSFER
ASE)		 5dl7 PORIN
(Acinetobacter
baumannii) 		5 / 12 ALA A 199
GLY A 187
HIS A 201
LEU A 197
SER A 189
 None
 1.50A 3bxoB-5dl7A:
undetectable		 3bxoB-5dl7A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 5dl7 PORIN
(Acinetobacter
baumannii) 		5 / 11 ILE A 170
ASP A 168
GLY A 283
VAL A 288
ARG A 331
 None
 1.06A 4ac9B-5dl7A:
undetectable
4ac9C-5dl7A:
undetectable		 4ac9B-5dl7A:
22.84
4ac9C-5dl7A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 5dl7 PORIN
(Acinetobacter
baumannii) 		3 / 3 ARG A  19
ASP A 158
GLN A 156
 None
 0.77A 4azsA-5dl7A:
undetectable		 4azsA-5dl7A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5dl7 PORIN
(Acinetobacter
baumannii) 		4 / 8 ASP A 291
ARG A 198
GLU A 310
ASP A 230
 None
 1.05A 4gkhF-5dl7A:
undetectable		 4gkhF-5dl7A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 5dl7 PORIN
(Acinetobacter
baumannii) 		5 / 12 LEU A  10
GLY A  37
PHE A  40
ALA A  35
ASN A  14
 None
None
None
None
C8E  A 510 (-4.1A)
 1.38A 4pclB-5dl7A:
undetectable		 4pclB-5dl7A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5dl7 PORIN
(Acinetobacter
baumannii) 		3 / 3 ASP A 168
ARG A 395
ARG A  19
 None
 0.84A 4x5iA-5dl7A:
undetectable		 4x5iA-5dl7A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5dl7 PORIN
(Acinetobacter
baumannii) 		4 / 4 GLY A 268
VAL A 304
PHE A 233
ILE A 252
 None
 1.14A 4xv2B-5dl7A:
undetectable		 4xv2B-5dl7A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 5dl7 PORIN
(Acinetobacter
baumannii) 		3 / 3 ARG A  87
ASP A  33
TYR A  73
 None
 0.86A 4yo9B-5dl7A:
undetectable		 4yo9B-5dl7A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5dl7 PORIN
(Acinetobacter
baumannii) 		5 / 12 GLY A  62
GLY A  92
PRO A  80
LEU A  38
LEU A 126
 None
 1.08A 5bw4A-5dl7A:
undetectable		 5bw4A-5dl7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 5dl7 PORIN
(Acinetobacter
baumannii) 		4 / 6 ILE A 207
TYR A 208
PHE A 174
THR A 284
 None
 1.28A 5g08A-5dl7A:
undetectable		 5g08A-5dl7A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5dl7 PORIN
(Acinetobacter
baumannii) 		4 / 6 PHE A 292
PHE A 348
VAL A 304
ASP A 351
 None
 1.20A 5hesA-5dl7A:
undetectable		 5hesA-5dl7A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5dl7 PORIN
(Acinetobacter
baumannii) 		5 / 12 PRO A 117
THR A 185
PHE A 212
GLY A 187
SER A 189
 None
 1.36A 5hfjC-5dl7A:
undetectable		 5hfjC-5dl7A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5dl7 PORIN
(Acinetobacter
baumannii) 		5 / 12 PRO A 117
THR A 185
PHE A 212
GLY A 187
SER A 189
 None
 1.28A 5hfjG-5dl7A:
undetectable		 5hfjG-5dl7A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5dl7 PORIN
(Acinetobacter
baumannii) 		4 / 6 PHE A 127
PRO A 128
ARG A  13
THR A  11
 None
 1.40A 5ih0A-5dl7A:
undetectable		 5ih0A-5dl7A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 5dl7 PORIN
(Acinetobacter
baumannii) 		3 / 3 TRP A  34
MET A  66
ASN A  64
 C8E  A 510 (-3.7A)
C8E  A 510 ( 4.3A)
None
 1.22A 5uc1B-5dl7A:
undetectable		 5uc1B-5dl7A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 5dl7 PORIN
(Acinetobacter
baumannii) 		3 / 3 ARG A 374
ARG A  13
ARG A 125
 None
 0.99A 6bplA-5dl7A:
undetectable
6bplB-5dl7A:
undetectable		 6bplA-5dl7A:
12.68
6bplB-5dl7A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 5dl7 PORIN
(Acinetobacter
baumannii) 		5 / 12 ILE A 170
SER A 286
ASN A 380
PHE A 388
ASN A 171
 None
 1.27A 6dwnB-5dl7A:
undetectable		 6dwnB-5dl7A:
11.31