SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dl8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 5dl8 BENZOATE TRANSPORT
PORIN BENP
(Acinetobacter
baumannii) 		3 / 4 VAL B 115
TRP B 119
TRP B 138
 None
 1.18A 1gmkC-5dl8B:
undetectable
1gmkD-5dl8B:
undetectable		 1gmkC-5dl8B:
7.24
1gmkD-5dl8B:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 5dl8 BENZOATE TRANSPORT
PORIN BENP
(Acinetobacter
baumannii) 		5 / 12 ASN B 387
SER B  34
VAL B  83
ALA B  38
ALA B  70
 None
 1.01A 1n5xA-5dl8B:
undetectable		 1n5xA-5dl8B:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 5dl8 BENZOATE TRANSPORT
PORIN BENP
(Acinetobacter
baumannii) 		5 / 12 ASN B 387
SER B  34
VAL B  83
ALA B  38
ALA B  70
 None
 1.01A 1n5xB-5dl8B:
undetectable		 1n5xB-5dl8B:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5dl8 BENZOATE TRANSPORT
PORIN BENP
(Acinetobacter
baumannii) 		5 / 12 TYR B 187
TYR B 137
VAL B 157
PHE B 236
TYR B 203
 None
 1.43A 3apwA-5dl8B:
undetectable		 3apwA-5dl8B:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5dl8 BENZOATE TRANSPORT
PORIN BENP
(Acinetobacter
baumannii) 		5 / 9 LEU B 134
THR B 135
TYR B 137
PHE B 171
GLY B 283
 None
 1.43A 3jusB-5dl8B:
undetectable		 3jusB-5dl8B:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5dl8 BENZOATE TRANSPORT
PORIN BENP
(Acinetobacter
baumannii) 		4 / 7 GLU B 345
TYR B 329
GLU B 343
GLU B 303
 None
 1.22A 4mi4A-5dl8B:
undetectable
4mi4C-5dl8B:
undetectable		 4mi4A-5dl8B:
17.68
4mi4C-5dl8B:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5dl8 BENZOATE TRANSPORT
PORIN BENP
(Acinetobacter
baumannii) 		4 / 6 GLU B 345
TYR B 329
GLU B 343
GLU B 303
 None
 1.15A 4r87H-5dl8B:
undetectable		 4r87H-5dl8B:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 5dl8 BENZOATE TRANSPORT
PORIN BENP
(Acinetobacter
baumannii) 		3 / 3 ARG B 383
ASP B 382
ARG B 368
 None
 0.70A 4wq4B-5dl8B:
undetectable		 4wq4B-5dl8B:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5dl8 BENZOATE TRANSPORT
PORIN BENP
(Acinetobacter
baumannii) 		4 / 7 ASP B 121
TYR B 289
GLU B 201
ASP B 189
 None
 1.36A 6mn5E-5dl8B:
undetectable		 6mn5E-5dl8B:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5dl8 BENZOATE TRANSPORT
PORIN BENP
(Acinetobacter
baumannii) 		4 / 7 TYR B 215
GLU B 201
ASP B 189
GLU B 153
 None
 1.31A 6mn5E-5dl8B:
undetectable		 6mn5E-5dl8B:
11.36