SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dld'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 9 GLU A 270
LEU A 246
ARG A 253
ILE A 211
LEU A 280
 None
 1.50A 1ereA-5dldA:
undetectable		 1ereA-5dldA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 PRO A 330
LEU A 332
THR A 311
ARG A 309
 None
None
None
ACT  A 505 (-4.1A)
 1.35A 1i2wA-5dldA:
undetectable		 1i2wA-5dldA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 11 LEU A  20
ALA A  23
ALA A 362
THR A 173
VAL A 117
 None
 1.13A 1ictA-5dldA:
undetectable
1ictC-5dldA:
undetectable		 1ictA-5dldA:
17.13
1ictC-5dldA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 8 SER A 363
ILE A  15
PHE A  51
MET A 184
 None
UDP  A 501 (-3.7A)
None
None
 1.15A 1kb9A-5dldA:
undetectable
1kb9C-5dldA:
undetectable
1kb9D-5dldA:
undetectable
1kb9E-5dldA:
undetectable		 1kb9A-5dldA:
24.33
1kb9C-5dldA:
22.08
1kb9D-5dldA:
20.05
1kb9E-5dldA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 11 THR A 150
GLY A 120
GLU A 118
GLU A 296
ASN A 156
 None
 1.29A 1odiD-5dldA:
undetectable		 1odiD-5dldA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 11 THR A 150
GLY A 120
GLU A 118
GLU A 296
ASN A 156
 None
 1.29A 1odiF-5dldA:
undetectable		 1odiF-5dldA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 VAL A 164
GLY A 165
VAL A 167
TRP A 145
 None
 1.37A 1tkqB-5dldA:
undetectable		 1tkqB-5dldA:
2.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 SER A 104
VAL A 142
VAL A 103
SER A 143
 None
 1.16A 2j9cA-5dldA:
undetectable
2j9cB-5dldA:
undetectable
2j9cC-5dldA:
undetectable		 2j9cA-5dldA:
14.29
2j9cB-5dldA:
14.29
2j9cC-5dldA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		3 / 3 PRO A 299
PHE A 286
LYS A 303
 None
 1.21A 3bjwG-5dldA:
undetectable		 3bjwG-5dldA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		6 / 12 THR A 100
ILE A 114
GLY A 115
HIS A 116
ASN A 135
LEU A 105
 None
 1.49A 3eeyA-5dldA:
3.9		 3eeyA-5dldA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		6 / 12 THR A 100
ILE A 114
GLY A 115
HIS A 116
ASN A 135
LEU A 105
 None
 1.47A 3eeyB-5dldA:
3.9		 3eeyB-5dldA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		6 / 12 THR A 100
ILE A 114
GLY A 115
HIS A 116
ASN A 135
LEU A 105
 None
 1.49A 3eeyC-5dldA:
4.1		 3eeyC-5dldA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		6 / 12 THR A 100
ILE A 114
GLY A 115
HIS A 116
ASN A 135
LEU A 105
 None
 1.49A 3eeyD-5dldA:
4.0		 3eeyD-5dldA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		6 / 12 THR A 100
ILE A 114
GLY A 115
HIS A 116
ASN A 135
LEU A 105
 None
 1.47A 3eeyI-5dldA:
3.8		 3eeyI-5dldA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		6 / 12 THR A 100
ILE A 114
GLY A 115
HIS A 116
ASN A 135
LEU A 105
 None
 1.49A 3eeyJ-5dldA:
4.1		 3eeyJ-5dldA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 8 TYR A 357
LEU A 178
SER A 354
ASN A 355
 None
 0.97A 3lm8A-5dldA:
2.2
3lm8C-5dldA:
2.8		 3lm8A-5dldA:
21.01
3lm8C-5dldA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 12 GLY A  95
MET A  17
LEU A   6
THR A  37
ILE A  75
 None
 1.25A 3mneA-5dldA:
undetectable		 3mneA-5dldA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 11 TYR A 111
LYS A   2
ILE A 114
ALA A 107
ASP A  89
 GOL  A 508 ( 4.1A)
None
None
None
None
 1.11A 3nmuB-5dldA:
1.9
3nmuJ-5dldA:
3.6		 3nmuB-5dldA:
23.33
3nmuJ-5dldA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 12 ILE A 294
GLY A 292
GLY A 293
THR A 212
LEU A 210
 None
UDP  A 501 (-3.7A)
UDP  A 501 (-3.7A)
UDP  A 501 (-4.7A)
None
 1.02A 3uboB-5dldA:
6.1		 3uboB-5dldA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		3 / 3 ARG A 309
ARG A 136
ASP A 125
 ACT  A 505 (-4.1A)
ACT  A 505 (-3.6A)
None
 1.01A 3wipG-5dldA:
undetectable
3wipH-5dldA:
undetectable		 3wipG-5dldA:
20.76
3wipH-5dldA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 6 GLU A 316
THR A 173
HIS A  94
LEU A 121
 None
 1.00A 4pgfA-5dldA:
6.1		 4pgfA-5dldA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 8 ASN A 251
PRO A 250
PHE A 219
TYR A 244
 None
UD1  A 502 (-4.6A)
None
None
 1.36A 4v2zC-5dldA:
undetectable		 4v2zC-5dldA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 12 THR A  99
LEU A 101
ALA A 102
LEU A  76
LEU A  61
 None
 0.86A 4xi3C-5dldA:
undetectable		 4xi3C-5dldA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 7 THR A  73
LEU A  76
THR A  98
LEU A 101
 None
None
UD1  A 502 (-4.2A)
None
 0.96A 4z91F-5dldA:
undetectable
4z91G-5dldA:
undetectable
4z91H-5dldA:
undetectable
4z91I-5dldA:
undetectable
4z91J-5dldA:
undetectable		 4z91F-5dldA:
22.83
4z91G-5dldA:
22.83
4z91H-5dldA:
22.83
4z91I-5dldA:
22.83
4z91J-5dldA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 12 ILE A 288
ALA A 337
ALA A 240
ARG A 207
PHE A 226
 None
None
None
None
EDO  A 503 (-3.6A)
 1.24A 4zo1X-5dldA:
undetectable		 4zo1X-5dldA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 6 ASP A 290
PRO A 255
TYR A 244
LEU A 260
 EDO  A 503 (-3.2A)
None
None
None
 1.30A 5bmvB-5dldA:
7.3		 5bmvB-5dldA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		3 / 3 ALA A 153
ASN A 156
LEU A 157
 None
 0.37A 5i1nB-5dldA:
undetectable		 5i1nB-5dldA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 HIS A 247
LEU A  48
TYR A 274
PHE A 277
 UD1  A 502 (-4.0A)
None
UDP  A 501 (-4.4A)
UDP  A 501 (-3.6A)
 1.15A 5igjA-5dldA:
undetectable		 5igjA-5dldA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 6 VAL A  93
LEU A 134
ARG A 122
ILE A 126
 None
 1.03A 5jw1A-5dldA:
undetectable		 5jw1A-5dldA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		3 / 3 THR A 311
SER A 123
ASP A  96
 None
None
ACT  A 505 (-3.0A)
 0.79A 5kvaA-5dldA:
4.0		 5kvaA-5dldA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		3 / 3 THR A 311
SER A 123
ASP A  96
 None
None
ACT  A 505 (-3.0A)
 0.76A 5kvaB-5dldA:
4.0		 5kvaB-5dldA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 7 VAL A  91
PHE A  83
THR A 100
THR A  99
 None
 0.72A 5m78A-5dldA:
undetectable		 5m78A-5dldA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 ARG A 283
THR A 205
ALA A 206
ASP A 203
 None
 1.14A 5mfxA-5dldA:
2.6		 5mfxA-5dldA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1471_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 12 ARG A 309
ARG A 215
ASN A 135
THR A 100
HIS A 116
 ACT  A 505 (-4.1A)
UDP  A 501 (-3.1A)
None
None
None
 1.41A 5x7pA-5dldA:
0.1		 5x7pA-5dldA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 4 VAL A  91
LEU A   5
LEU A  86
ASP A  31
 None
 1.41A 5xv7A-5dldA:
undetectable		 5xv7A-5dldA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 7 ARG A 154
THR A 150
PRO A 149
PRO A 315
 None
 1.49A 6a4iB-5dldA:
undetectable		 6a4iB-5dldA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 LEU A 325
THR A 289
ARG A 339
ARG A 352
 ACT  A 506 (-3.9A)
None
None
None
 1.35A 6ew0B-5dldA:
6.5		 6ew0B-5dldA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 LEU A 325
THR A 289
ARG A 339
ARG A 352
 ACT  A 506 (-3.9A)
None
None
None
 1.35A 6ew0D-5dldA:
6.5		 6ew0D-5dldA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 LEU A 325
THR A 289
ARG A 339
ARG A 352
 ACT  A 506 (-3.9A)
None
None
None
 1.35A 6ew0H-5dldA:
undetectable		 6ew0H-5dldA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 LEU A 325
THR A 289
ARG A 339
ARG A 352
 ACT  A 506 (-3.9A)
None
None
None
 1.35A 6ew0I-5dldA:
undetectable		 6ew0I-5dldA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 6 THR A  10
LEU A  44
MET A  17
THR A 100
LEU A  61
 UD1  A 502 ( 4.2A)
None
None
None
None
 1.36A 6mvxA-5dldA:
undetectable
6mvxB-5dldA:
undetectable
6mvxC-5dldA:
undetectable		 6mvxA-5dldA:
20.49
6mvxB-5dldA:
20.49
6mvxC-5dldA:
20.49