SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dlm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 5dlm HEAVY CHAIN OF
MONOCLONAL ANTIBODY
(Mus
musculus) 		3 / 3 ALA H  33
VAL H  96
TRP H  36
 None
 0.90A 1gmkA-5dlmH:
undetectable
1gmkB-5dlmH:
undetectable		 1gmkA-5dlmH:
13.04
1gmkB-5dlmH:
13.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 5dlm HEAVY CHAIN OF
MONOCLONAL ANTIBODY
(Mus
musculus) 		5 / 10 TRP H  47
SER H  50
TYR H  58
GLY H  98
TRP H 105
 None
 0.85A 3ls4H-5dlmH:
28.0		 3ls4H-5dlmH:
86.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5dlm HEAVY CHAIN OF
MONOCLONAL ANTIBODY
(Mus
musculus) 		5 / 12 GLY H 106
GLN H   6
MET H  34
VAL H  78
LEU H  29
 None
 1.35A 3mnoA-5dlmH:
undetectable		 3mnoA-5dlmH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5dlm HEAVY CHAIN OF
MONOCLONAL ANTIBODY
(Mus
musculus) 		5 / 12 GLY H 106
GLN H   6
MET H  34
VAL H  78
LEU H  29
 None
 1.37A 3mnpA-5dlmH:
undetectable		 3mnpA-5dlmH:
17.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 5dlm HEAVY CHAIN OF
MONOCLONAL ANTIBODY
(Mus
musculus) 		3 / 3 TYR H  59
GLY H  65
THR H  68
 None
 0.15A 6cjkB-5dlmH:
25.2		 6cjkB-5dlmH:
58.37