SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dm3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		4 / 4 HIS A 228
LEU A 193
LEU A 189
LEU A 148
 None
 1.23A 1a4lD-5dm3A:
undetectable		 1a4lD-5dm3A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 368
GLY A 366
LEU A 128
ALA A 363
SER A 266
 None
None
None
None
ADP  A 501 (-2.9A)
 0.98A 1dfoA-5dm3A:
undetectable		 1dfoA-5dm3A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 368
GLY A 366
LEU A 128
ALA A 363
SER A 266
 None
None
None
None
ADP  A 501 (-2.9A)
 0.97A 1dfoB-5dm3A:
undetectable		 1dfoB-5dm3A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 368
GLY A 366
LEU A 128
ALA A 363
SER A 266
 None
None
None
None
ADP  A 501 (-2.9A)
 0.98A 1dfoC-5dm3A:
undetectable		 1dfoC-5dm3A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 368
GLY A 366
LEU A 128
ALA A 363
SER A 266
 None
None
None
None
ADP  A 501 (-2.9A)
 0.98A 1dfoD-5dm3A:
undetectable		 1dfoD-5dm3A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 ALA A 365
ILE A 216
PHE A 305
ARG A 121
LEU A 222
 None
 1.38A 1eiiA-5dm3A:
undetectable		 1eiiA-5dm3A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 368
GLY A 366
LEU A 128
ALA A 363
SER A 266
 None
None
None
None
ADP  A 501 (-2.9A)
 1.01A 1eqbA-5dm3A:
undetectable		 1eqbA-5dm3A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 368
GLY A 366
LEU A 128
ALA A 363
SER A 266
 None
None
None
None
ADP  A 501 (-2.9A)
 1.01A 1eqbB-5dm3A:
undetectable		 1eqbB-5dm3A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 368
GLY A 366
LEU A 128
ALA A 363
SER A 266
 None
None
None
None
ADP  A 501 (-2.9A)
 1.01A 1eqbC-5dm3A:
undetectable		 1eqbC-5dm3A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 368
GLY A 366
LEU A 128
ALA A 363
SER A 266
 None
None
None
None
ADP  A 501 (-2.9A)
 1.01A 1eqbD-5dm3A:
undetectable		 1eqbD-5dm3A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		3 / 4 LYS A 373
ALA A 370
MET A 413
 None
 0.93A 1hk3A-5dm3A:
undetectable		 1hk3A-5dm3A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 PRO A 323
GLY A 355
GLY A 354
PHE A 147
SER A 312
 None
 1.23A 1wg8A-5dm3A:
undetectable		 1wg8A-5dm3A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD205_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 10 ALA A 307
LEU A 306
MET A 418
MET A 413
SER A 411
 None
 1.17A 1wrlC-5dm3A:
undetectable
1wrlD-5dm3A:
undetectable		 1wrlC-5dm3A:
10.14
1wrlD-5dm3A:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		4 / 4 VAL A  27
LEU A 193
ILE A 216
LEU A 144
 None
 1.01A 2byoA-5dm3A:
undetectable		 2byoA-5dm3A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_B_CLUB809_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		4 / 6 ALA A 119
MET A 418
TYR A 426
HIS A 118
 None
 1.46A 2pncB-5dm3A:
undetectable		 2pncB-5dm3A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		3 / 3 ASN A 359
LEU A 358
HIS A 228
 None
 0.70A 2q6fB-5dm3A:
undetectable		 2q6fB-5dm3A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 368
GLY A 366
LEU A 128
ALA A 363
SER A 266
 None
None
None
None
ADP  A 501 (-2.9A)
 0.96A 2vmyA-5dm3A:
undetectable		 2vmyA-5dm3A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 10 ALA A 221
ALA A 225
THR A 229
LEU A 104
VAL A  27
 None
 1.37A 2wuzA-5dm3A:
undetectable		 2wuzA-5dm3A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 10 ALA A 221
ALA A 225
THR A 229
LEU A 104
VAL A  27
 None
 1.38A 2wuzB-5dm3A:
undetectable		 2wuzB-5dm3A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		4 / 6 VAL A 432
GLN A  30
PHE A 437
ARG A 428
 None
 1.17A 3bjwF-5dm3A:
undetectable		 3bjwF-5dm3A:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		3 / 3 SER A 259
SER A 250
HIS A 262
 None
 0.84A 3mzeA-5dm3A:
undetectable		 3mzeA-5dm3A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 ALA A 239
TRP A  96
SER A 152
LEU A 148
ALA A 234
 None
 1.07A 3ou6A-5dm3A:
undetectable		 3ou6A-5dm3A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 ALA A 239
TRP A  96
SER A 152
LEU A 148
ALA A 234
 None
 1.07A 3ou6B-5dm3A:
undetectable		 3ou6B-5dm3A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 ALA A 239
TRP A  96
SER A 152
LEU A 148
ALA A 234
 None
 1.09A 3ou6C-5dm3A:
undetectable		 3ou6C-5dm3A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 ALA A 239
TRP A  96
SER A 152
LEU A 148
ALA A 234
 None
 1.04A 3ou7B-5dm3A:
undetectable		 3ou7B-5dm3A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 ALA A 239
TRP A  96
SER A 152
LEU A 148
ALA A 234
 None
 1.05A 3ou7C-5dm3A:
undetectable		 3ou7C-5dm3A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 11 PHE A 275
LEU A 131
LEU A 136
LEU A 295
ILE A 375
 None
 1.10A 4dm8A-5dm3A:
undetectable		 4dm8A-5dm3A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		4 / 7 ARG A 190
THR A 179
THR A 203
GLY A 205
 None
 0.77A 4eq4A-5dm3A:
undetectable		 4eq4A-5dm3A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		4 / 8 ARG A 190
THR A 179
THR A 203
GLY A 205
 None
 0.85A 4eq4B-5dm3A:
undetectable		 4eq4B-5dm3A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		4 / 7 ARG A 190
THR A 179
THR A 203
GLY A 205
 None
 0.81A 4eqlA-5dm3A:
undetectable		 4eqlA-5dm3A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		4 / 7 ARG A 190
THR A 179
THR A 203
GLY A 205
 None
 0.83A 4eqlB-5dm3A:
undetectable		 4eqlB-5dm3A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		4 / 7 ARG A 190
THR A 179
THR A 203
GLY A 205
 None
 0.87A 4l39B-5dm3A:
undetectable		 4l39B-5dm3A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 ASP A 357
TYR A 309
SER A 312
ALA A 429
ALA A 430
 None
 1.49A 4u15B-5dm3A:
undetectable		 4u15B-5dm3A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		4 / 7 ARG A 315
SER A 260
GLU A 206
GLU A 145
 None
 1.27A 4xzkA-5dm3A:
undetectable		 4xzkA-5dm3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		3 / 3 LEU A 408
ARG A 409
ARG A 415
 None
 0.46A 4yiaB-5dm3A:
undetectable		 4yiaB-5dm3A:
5.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 ASP A 424
LEU A 434
ALA A 430
ARG A 415
GLY A 410
 None
 0.96A 5m5cB-5dm3A:
undetectable		 5m5cB-5dm3A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 ILE A 375
GLY A 374
GLY A 294
SER A 266
HIS A 290
 None
None
None
ADP  A 501 (-2.9A)
None
 1.01A 5twjA-5dm3A:
undetectable		 5twjA-5dm3A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 10 ILE A 375
GLY A 374
GLY A 294
SER A 266
HIS A 290
 None
None
None
ADP  A 501 (-2.9A)
None
 1.04A 5twjB-5dm3A:
undetectable		 5twjB-5dm3A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 10 ILE A 375
GLY A 374
LEU A 267
SER A 266
HIS A 290
 None
None
None
ADP  A 501 (-2.9A)
None
 1.15A 5twjB-5dm3A:
undetectable		 5twjB-5dm3A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		3 / 3 GLY A 258
THR A 326
PRO A 323
 None
 0.66A 5v5zA-5dm3A:
undetectable		 5v5zA-5dm3A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 12 ALA A 407
GLY A 410
SER A 411
LEU A 414
ASP A 424
 None
 1.30A 5vlmF-5dm3A:
undetectable		 5vlmF-5dm3A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 5dm3 L-GLUTAMINE
SYNTHETASE
(Chromohalobacter
salexigens) 		5 / 9 GLY A 371
ALA A 369
GLY A 374
LEU A 379
GLU A 376
 None
 1.16A 5vw4A-5dm3A:
undetectable		 5vw4A-5dm3A:
19.58