SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dm5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 5dm5 PUTATIVE ACYL-COA
THIOESTER HYDROLASE
(Yersinia
pestis) 		3 / 3 TRP A 102
GLN A  44
THR A 118
 None
 0.99A 4m2xA-5dm5A:
undetectable		 4m2xA-5dm5A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5dm5 PUTATIVE ACYL-COA
THIOESTER HYDROLASE
(Yersinia
pestis) 		3 / 3 LEU A  21
GLN A  44
LYS A  54
 None
 0.82A 6exiB-5dm5A:
undetectable		 6exiB-5dm5A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5dm5 PUTATIVE ACYL-COA
THIOESTER HYDROLASE
(Yersinia
pestis) 		3 / 3 LEU A  21
GLN A  44
LYS A  54
 None
 0.85A 6exiA-5dm5A:
undetectable		 6exiA-5dm5A:
18.49