SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dm7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 5dm7 50S RIBOSOMAL
PROTEIN L5
(Deinococcus
radiodurans) 		5 / 10 GLU D  56
ALA D  54
LEU D  57
GLU D  38
LEU D  40
 None
 1.47A 1a29A-5dm7D:
undetectable		 1a29A-5dm7D:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 5dm7 50S RIBOSOMAL
PROTEIN L5
(Deinococcus
radiodurans) 		4 / 7 GLU D  56
LEU D  57
GLU D  38
LEU D  40
 None
 0.90A 1linA-5dm7D:
undetectable		 1linA-5dm7D:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 5dm7 50S RIBOSOMAL
PROTEIN L15
(Deinococcus
radiodurans) 		4 / 8 GLU I  94
VAL I 106
ARG I 139
ASP I 123
 None
 1.28A 1s3zA-5dm7I:
undetectable
1s3zB-5dm7I:
undetectable		 1s3zA-5dm7I:
23.03
1s3zB-5dm7I:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5dm7 50S RIBOSOMAL
PROTEIN L27
(Deinococcus
radiodurans) 		4 / 7 ILE T  36
PHE T  69
PHE T  45
GLY T  54
 A  X2333 ( 3.9A)
C  X 869 ( 3.5A)
None
C  X2343 ( 3.2A)
 0.96A 3em0B-5dm7T:
undetectable		 3em0B-5dm7T:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 5dm7 50S RIBOSOMAL
PROTEIN L5
(Deinococcus
radiodurans) 		3 / 3 ARG D 115
ILE D 132
THR D 149
 None
 0.57A 3ia4D-5dm7D:
undetectable		 3ia4D-5dm7D:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5dm7 50S RIBOSOMAL
PROTEIN L20
(Deinococcus
radiodurans) 		5 / 12 ILE N  65
ALA N  67
LEU N  71
PHE N 106
ALA N 100
 None
 1.16A 3uvvB-5dm7N:
undetectable		 3uvvB-5dm7N:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5dm7 50S RIBOSOMAL
PROTEIN L32
(Deinococcus
radiodurans) 		4 / 8 SER Z  12
SER Z  14
ARG Z  16
MET Z  18
 U  X2004 ( 2.5A)
G  X  16 ( 3.2A)
C  X 527 ( 3.3A)
C  X2028 ( 3.8A)
 0.99A 4af0A-5dm7Z:
undetectable		 4af0A-5dm7Z:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5dm7 50S RIBOSOMAL
PROTEIN L5
(Deinococcus
radiodurans) 		5 / 12 GLU D  32
PHE D 177
ILE D 117
GLY D 174
LEU D 100
 A  Y  47 ( 4.6A)
None
None
None
None
 1.35A 5esgA-5dm7D:
undetectable		 5esgA-5dm7D:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 5dm7 50S RIBOSOMAL
PROTEIN L5
(Deinococcus
radiodurans) 		5 / 12 ILE D 154
LEU D 108
PHE D 177
ALA D 166
GLY D 126
 None
 1.13A 5uxdB-5dm7D:
undetectable		 5uxdB-5dm7D:
19.17