SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dmg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5dmg RB86 ANTIBODY FAB
FRAGMENT LIGHT CHAIN
(Oryctolagus
cuniculus) 		4 / 7 LEU L 598
GLY L 710
GLY L 712
THR L 581
 None
 0.80A 2wd9A-5dmgL:
undetectable		 2wd9A-5dmgL:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 5dmg RB86 ANTIBODY FAB
FRAGMENT LIGHT CHAIN
(Oryctolagus
cuniculus) 		3 / 3 GLY L 607
PRO L 606
ALA L 730
 None
 0.56A 4qn9B-5dmgL:
undetectable		 4qn9B-5dmgL:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5dmg RB86 ANTIBODY FAB
FRAGMENT LIGHT CHAIN
(Oryctolagus
cuniculus) 		4 / 5 VAL L 519
ILE L 521
VAL L 807
THR L 805
 None
 0.74A 4xdtA-5dmgL:
undetectable		 4xdtA-5dmgL:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 5dmg RB86 ANTIBODY FAB
FRAGMENT HEAVY CHAIN
(Oryctolagus
cuniculus) 		4 / 6 PRO H 114
GLY H 115
THR H 116
LYS H 316
 None
 1.03A 5xxiA-5dmgH:
undetectable		 5xxiA-5dmgH:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 5dmg RB86 ANTIBODY FAB
FRAGMENT HEAVY CHAIN
(Oryctolagus
cuniculus) 		3 / 3 PRO H1071
SER H1073
SER H1074
 None
 0.69A 6bpyA-5dmgH:
undetectable		 6bpyA-5dmgH:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5dmg RB86 ANTIBODY FAB
FRAGMENT HEAVY CHAIN
(Oryctolagus
cuniculus) 		5 / 12 VAL H1093
THR H1091
VAL H1097
GLY H1004
VAL H1038
 None
 1.04A 6drzA-5dmgH:
undetectable		 6drzA-5dmgH:
17.37