SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5dmi CHI220 FAB HEAVY
CHAIN
(Homo
sapiens;
Mus
musculus) 		5 / 10 PHE H 122
GLY H 118
THR H 217
VAL H 210
VAL H 219
 None
 1.21A 4jx1B-5dmiH:
undetectable		 4jx1B-5dmiH:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5dmi CHI220 FAB HEAVY
CHAIN
(Homo
sapiens;
Mus
musculus) 		5 / 12 SER H 199
GLY H 136
THR H 137
ALA H 138
THR H 131
 None
 1.20A 4qvyV-5dmiH:
undetectable
4qvyW-5dmiH:
undetectable		 4qvyV-5dmiH:
23.17
4qvyW-5dmiH:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5dmi CHI220 FAB HEAVY
CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 5 VAL H  18
ILE H  20
VAL H 109
THR H 107
 None
 0.75A 4xdtA-5dmiH:
undetectable		 4xdtA-5dmiH:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5dmi CHI220 FAB HEAVY
CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 4 GLY H  98
ARG H  94
ASN H  97
LEU H 100
 None
 1.44A 6b58A-5dmiH:
undetectable		 6b58A-5dmiH:
16.03