SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dmp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		4 / 6 PRO A  70
LYS A 165
ALA A 149
GLU A 136
 None
EDO  A 204 (-4.4A)
None
None
 1.13A 1qhyA-5dmpA:
undetectable		 1qhyA-5dmpA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		5 / 12 GLY A 198
ASP A 192
GLY A 101
ILE A  93
VAL A 105
 None
 0.68A 2ienB-5dmpA:
undetectable		 2ienB-5dmpA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		5 / 12 GLY A 198
ASP A 192
GLY A 101
ILE A  93
VAL A 105
 None
 0.80A 2q5kB-5dmpA:
undetectable		 2q5kB-5dmpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		4 / 5 GLU A  95
PRO A  94
ILE A  93
GLY A 100
 None
 1.17A 2qeuA-5dmpA:
undetectable
2qeuC-5dmpA:
undetectable		 2qeuA-5dmpA:
23.66
2qeuC-5dmpA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		4 / 6 GLY A 109
ILE A  34
ILE A  30
ASP A 107
 None
 0.93A 3a7eA-5dmpA:
undetectable		 3a7eA-5dmpA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		5 / 12 GLY A 198
ASP A 192
GLY A 101
ILE A  93
VAL A 105
 None
 0.90A 3cywA-5dmpA:
undetectable		 3cywA-5dmpA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		5 / 12 GLY A 198
ASP A 192
GLY A 101
ILE A  93
VAL A 105
 None
 0.76A 3jvyA-5dmpA:
undetectable		 3jvyA-5dmpA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		5 / 12 GLY A 198
ASP A 192
GLY A 101
ILE A  93
VAL A 105
 None
 0.87A 3nu3A-5dmpA:
undetectable		 3nu3A-5dmpA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		4 / 7 SER A  43
GLY A  99
GLY A 100
ALA A  42
 None
MG  A 208 ( 4.0A)
None
None
 0.65A 4yjiA-5dmpA:
undetectable		 4yjiA-5dmpA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		4 / 5 GLN A  38
THR A  88
THR A 110
LEU A  57
 None
 1.26A 6aphA-5dmpA:
undetectable		 6aphA-5dmpA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_2
(-)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		4 / 4 GLN A  38
THR A  88
THR A 110
LEU A  57
 None
 1.21A 6f3mA-5dmpA:
undetectable		 6f3mA-5dmpA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_2
(-)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		4 / 4 GLN A  38
THR A  88
THR A 110
LEU A  57
 None
 1.21A 6f3mC-5dmpA:
undetectable		 6f3mC-5dmpA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 5dmp UNCHARACTERIZED
PROTEIN
(Methanocella
paludicola) 		4 / 5 GLN A  38
THR A  88
THR A 110
LEU A  57
 None
 1.27A 6gbnB-5dmpA:
undetectable		 6gbnB-5dmpA:
18.95