SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dmr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
5 / 12 ALA A 538
GLY A 525
GLU A 616
LEU A 552
PRO A 553
None
1.14A 1mj2C-5dmrA:
undetectable
1mj2D-5dmrA:
undetectable
1mj2C-5dmrA:
21.26
1mj2D-5dmrA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
5 / 12 ALA A 538
GLY A 525
GLU A 616
LEU A 552
PRO A 553
None
1.19A 1mjoC-5dmrA:
undetectable
1mjoD-5dmrA:
undetectable
1mjoC-5dmrA:
21.26
1mjoD-5dmrA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.44A 1v54N-5dmrA:
undetectable
1v54P-5dmrA:
undetectable
1v54N-5dmrA:
15.89
1v54P-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.45A 2dysA-5dmrA:
undetectable
2dysC-5dmrA:
undetectable
2dysA-5dmrA:
15.89
2dysC-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.37A 2dysN-5dmrA:
undetectable
2dysP-5dmrA:
undetectable
2dysN-5dmrA:
15.89
2dysP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.44A 2dysN-5dmrA:
undetectable
2dysP-5dmrA:
undetectable
2dysN-5dmrA:
15.89
2dysP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.43A 2eijA-5dmrA:
undetectable
2eijC-5dmrA:
undetectable
2eijA-5dmrA:
15.89
2eijC-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.42A 2eikA-5dmrA:
undetectable
2eikC-5dmrA:
undetectable
2eikA-5dmrA:
15.89
2eikC-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.43A 2eikN-5dmrA:
undetectable
2eikP-5dmrA:
undetectable
2eikN-5dmrA:
15.89
2eikP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.46A 2eilA-5dmrA:
undetectable
2eilC-5dmrA:
undetectable
2eilA-5dmrA:
15.89
2eilC-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.43A 2eilN-5dmrA:
undetectable
2eilP-5dmrA:
undetectable
2eilN-5dmrA:
15.89
2eilP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.40A 2eimA-5dmrA:
undetectable
2eimC-5dmrA:
undetectable
2eimA-5dmrA:
15.89
2eimC-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.41A 2eimN-5dmrA:
undetectable
2eimP-5dmrA:
undetectable
2eimN-5dmrA:
15.89
2eimP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.43A 2einA-5dmrA:
undetectable
2einC-5dmrA:
undetectable
2einA-5dmrA:
15.89
2einC-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.36A 2einN-5dmrA:
undetectable
2einP-5dmrA:
undetectable
2einN-5dmrA:
15.89
2einP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.42A 2einN-5dmrA:
undetectable
2einP-5dmrA:
undetectable
2einN-5dmrA:
15.89
2einP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
5 / 10 ALA A 573
LEU A 509
LEU A 624
LEU A 570
LEU A 630
None
1.05A 2xn7A-5dmrA:
undetectable
2xn7B-5dmrA:
undetectable
2xn7A-5dmrA:
21.85
2xn7B-5dmrA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.44A 2y69A-5dmrA:
undetectable
2y69C-5dmrA:
undetectable
2y69A-5dmrA:
15.89
2y69C-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.36A 2zxwN-5dmrA:
undetectable
2zxwP-5dmrA:
undetectable
2zxwN-5dmrA:
15.89
2zxwP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.43A 3abkA-5dmrA:
undetectable
3abkC-5dmrA:
undetectable
3abkA-5dmrA:
15.89
3abkC-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.43A 3abkN-5dmrA:
undetectable
3abkP-5dmrA:
undetectable
3abkN-5dmrA:
15.89
3abkP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.35A 3abmN-5dmrA:
undetectable
3abmP-5dmrA:
undetectable
3abmN-5dmrA:
15.89
3abmP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.46A 3abmN-5dmrA:
undetectable
3abmP-5dmrA:
undetectable
3abmN-5dmrA:
15.89
3abmP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.46A 3ag1A-5dmrA:
undetectable
3ag1C-5dmrA:
undetectable
3ag1A-5dmrA:
15.89
3ag1C-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.44A 3ag1N-5dmrA:
undetectable
3ag1P-5dmrA:
undetectable
3ag1N-5dmrA:
15.89
3ag1P-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.45A 3ag2A-5dmrA:
undetectable
3ag2C-5dmrA:
undetectable
3ag2A-5dmrA:
15.89
3ag2C-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.39A 3ag2N-5dmrA:
undetectable
3ag2P-5dmrA:
undetectable
3ag2N-5dmrA:
15.89
3ag2P-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.45A 3ag2N-5dmrA:
undetectable
3ag2P-5dmrA:
undetectable
3ag2N-5dmrA:
15.89
3ag2P-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.44A 3ag3N-5dmrA:
undetectable
3ag3P-5dmrA:
undetectable
3ag3N-5dmrA:
15.89
3ag3P-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.45A 3ag4A-5dmrA:
undetectable
3ag4C-5dmrA:
undetectable
3ag4A-5dmrA:
15.89
3ag4C-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.38A 3ag4N-5dmrA:
undetectable
3ag4P-5dmrA:
undetectable
3ag4N-5dmrA:
15.89
3ag4P-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.44A 3ag4N-5dmrA:
undetectable
3ag4P-5dmrA:
undetectable
3ag4N-5dmrA:
15.89
3ag4P-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)
5dmr EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1
REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus;
Mus
musculus)
5 / 12 ILE B 294
ALA A 591
LEU A 621
GLU B 398
TYR A 586
None
1.43A 3eigA-5dmrB:
undetectable
3eigA-5dmrB:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5dmr EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1

(Mus
musculus)
4 / 6 ILE B 319
THR B 308
PHE B 402
TYR B 290
None
1.19A 3elzB-5dmrB:
undetectable
3elzB-5dmrB:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
3 / 3 ASP A 524
ASN A 649
SER A 526
None
0.91A 3lslA-5dmrA:
undetectable
3lslD-5dmrA:
undetectable
3lslA-5dmrA:
25.00
3lslD-5dmrA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
3 / 3 SER A 526
ASP A 524
ASN A 649
None
0.84A 3lslA-5dmrA:
undetectable
3lslD-5dmrA:
undetectable
3lslA-5dmrA:
25.00
3lslD-5dmrA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
3 / 3 THR A 556
SER A 557
ARG A 560
None
0.83A 3phnA-5dmrA:
undetectable
3phnA-5dmrA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)
5dmr EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1

(Mus
musculus)
4 / 4 TYR B 290
THR B 308
VAL B 322
ILE B 412
None
1.47A 4jx1F-5dmrB:
undetectable
4jx1F-5dmrB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)
5dmr EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1

(Mus
musculus)
4 / 6 LEU B 389
LEU B 326
THR B 308
VAL B 317
None
1.08A 4udaA-5dmrB:
undetectable
4udaA-5dmrB:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.38A 5b1aN-5dmrA:
undetectable
5b1aP-5dmrA:
undetectable
5b1aN-5dmrA:
15.89
5b1aP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.45A 5b1aN-5dmrA:
undetectable
5b1aP-5dmrA:
undetectable
5b1aN-5dmrA:
15.89
5b1aP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.37A 5b1bN-5dmrA:
undetectable
5b1bP-5dmrA:
undetectable
5b1bN-5dmrA:
15.89
5b1bP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.44A 5b1bN-5dmrA:
undetectable
5b1bP-5dmrA:
undetectable
5b1bN-5dmrA:
15.89
5b1bP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.39A 5b3sN-5dmrA:
undetectable
5b3sP-5dmrA:
undetectable
5b3sN-5dmrA:
15.89
5b3sP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.44A 5b3sN-5dmrA:
undetectable
5b3sP-5dmrA:
undetectable
5b3sN-5dmrA:
15.89
5b3sP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.37A 5iy5A-5dmrA:
undetectable
5iy5C-5dmrA:
undetectable
5iy5A-5dmrA:
15.89
5iy5C-5dmrA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.43A 5iy5A-5dmrA:
undetectable
5iy5C-5dmrA:
undetectable
5iy5A-5dmrA:
15.89
5iy5C-5dmrA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.38A 5x19N-5dmrA:
undetectable
5x19P-5dmrA:
undetectable
5x19N-5dmrA:
15.89
5x19P-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.44A 5x19N-5dmrA:
undetectable
5x19P-5dmrA:
undetectable
5x19N-5dmrA:
15.89
5x19P-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.41A 5x1fN-5dmrA:
undetectable
5x1fP-5dmrA:
undetectable
5x1fN-5dmrA:
15.89
5x1fP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.39A 6nknA-5dmrA:
undetectable
6nknC-5dmrA:
undetectable
6nknA-5dmrA:
15.89
6nknC-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.41A 6nmfN-5dmrA:
undetectable
6nmfP-5dmrA:
undetectable
6nmfN-5dmrA:
15.89
6nmfP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.45A 6nmfN-5dmrA:
undetectable
6nmfP-5dmrA:
undetectable
6nmfN-5dmrA:
15.89
6nmfP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.35A 6nmpA-5dmrA:
undetectable
6nmpC-5dmrA:
undetectable
6nmpA-5dmrA:
15.89
6nmpC-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 6 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.44A 6nmpA-5dmrA:
undetectable
6nmpC-5dmrA:
undetectable
6nmpA-5dmrA:
15.89
6nmpC-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 ASP A 524
THR A 523
TYR A 522
HIS A 592
None
1.38A 6nmpN-5dmrA:
undetectable
6nmpP-5dmrA:
undetectable
6nmpN-5dmrA:
15.89
6nmpP-5dmrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5dmr REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H P80

(Murine
leukemia
virus)
4 / 7 HIS A 592
ASP A 583
THR A 582
TYR A 581
None
1.47A 6nmpN-5dmrA:
undetectable
6nmpP-5dmrA:
undetectable
6nmpN-5dmrA:
15.89
6nmpP-5dmrA:
22.48