SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dmx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		5 / 12 SER A  94
VAL A  91
GLY A  90
GLY A  73
LEU A  82
 None
 0.97A 1fduA-5dmxA:
2.5		 1fduA-5dmxA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		4 / 6 ARG A 241
PHE A 188
GLN A 192
PRO A 193
 None
 1.08A 2qqtA-5dmxA:
undetectable		 2qqtA-5dmxA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_B_DMOB700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		4 / 5 ASP A  33
CYH A 296
ASP A 293
PHE A 292
 None
 1.45A 2todA-5dmxA:
undetectable
2todB-5dmxA:
undetectable		 2todA-5dmxA:
22.43
2todB-5dmxA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_C_DMOC700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		4 / 5 CYH A 296
ASP A 293
PHE A 292
ASP A  33
 None
 1.44A 2todC-5dmxA:
undetectable
2todD-5dmxA:
undetectable		 2todC-5dmxA:
22.43
2todD-5dmxA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		4 / 6 ARG A 241
PHE A 188
GLN A 192
PRO A 193
 None
 1.06A 3gclA-5dmxA:
undetectable		 3gclA-5dmxA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		5 / 9 ALA A  30
ALA A  34
LEU A 295
SER A  24
VAL A  64
 None
 1.38A 4or0A-5dmxA:
undetectable		 4or0A-5dmxA:
19.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		4 / 6 ARG A 253
GLY A 274
SER A 279
LEU A 280
 None
 0.46A 5bphA-5dmxA:
31.3		 5bphA-5dmxA:
53.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		4 / 7 ARG A 253
GLY A 274
SER A 279
LEU A 280
 None
 0.71A 5bphB-5dmxA:
31.3		 5bphB-5dmxA:
53.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		4 / 6 ARG A 253
GLY A 274
SER A 279
LEU A 280
 None
 0.62A 5bphD-5dmxA:
31.4		 5bphD-5dmxA:
53.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  36
GLY A  39
LEU A  32
ARG A  60
ALA A  42
 None
 0.89A 5o96G-5dmxA:
2.4		 5o96G-5dmxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		5 / 12 ALA A 248
GLY A 191
ILE A  96
ASP A  72
GLY A  70
 None
 1.10A 5wwsB-5dmxA:
undetectable		 5wwsB-5dmxA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  97
ARG A 241
ILE A 186
GLY A 252
ALA A 242
 None
 1.05A 6c2mA-5dmxA:
undetectable		 6c2mA-5dmxA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  97
ARG A 241
ILE A 186
GLY A 252
ALA A 242
 None
 1.20A 6c2mB-5dmxA:
undetectable		 6c2mB-5dmxA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		5 / 10 GLY A  88
GLY A  90
VAL A 272
THR A  87
ILE A 299
 None
 1.15A 6exiA-5dmxA:
undetectable		 6exiA-5dmxA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		5 / 10 GLY A  88
GLY A  90
VAL A 272
THR A  87
ILE A 299
 None
 1.13A 6exiB-5dmxA:
undetectable		 6exiB-5dmxA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  88
GLY A  90
VAL A 272
THR A  87
ILE A 299
 None
 1.17A 6exiC-5dmxA:
undetectable
6exiD-5dmxA:
undetectable		 6exiC-5dmxA:
15.06
6exiD-5dmxA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  88
GLY A  90
VAL A 272
THR A  87
ILE A 299
 None
 1.13A 6exiC-5dmxA:
undetectable
6exiD-5dmxA:
undetectable		 6exiC-5dmxA:
15.06
6exiD-5dmxA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5dmx D-ALANINE--D-ALANINE
LIGASE
(Acinetobacter
baumannii) 		4 / 8 ASP A  33
GLY A  16
SER A  18
VAL A  23
 None
 1.02A 6giqL-5dmxA:
undetectable
6giqP-5dmxA:
undetectable
6giqT-5dmxA:
undetectable		 6giqL-5dmxA:
22.15
6giqP-5dmxA:
21.20
6giqT-5dmxA:
12.50