SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.36A 1c9sA-5dmyA:
undetectable
1c9sK-5dmyA:
undetectable		 1c9sA-5dmyA:
6.41
1c9sK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 1c9sA-5dmyA:
undetectable
1c9sB-5dmyA:
undetectable		 1c9sA-5dmyA:
6.41
1c9sB-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.41A 1c9sB-5dmyA:
undetectable
1c9sC-5dmyA:
undetectable		 1c9sB-5dmyA:
6.41
1c9sC-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 1c9sC-5dmyA:
undetectable
1c9sD-5dmyA:
undetectable		 1c9sC-5dmyA:
6.41
1c9sD-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 1c9sD-5dmyA:
undetectable
1c9sE-5dmyA:
undetectable		 1c9sD-5dmyA:
6.41
1c9sE-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 1c9sE-5dmyA:
undetectable
1c9sF-5dmyA:
undetectable		 1c9sE-5dmyA:
6.41
1c9sF-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 1c9sF-5dmyA:
undetectable
1c9sG-5dmyA:
undetectable		 1c9sF-5dmyA:
6.41
1c9sG-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 1c9sG-5dmyA:
undetectable
1c9sH-5dmyA:
undetectable		 1c9sG-5dmyA:
6.41
1c9sH-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.36A 1c9sH-5dmyA:
undetectable
1c9sI-5dmyA:
undetectable		 1c9sH-5dmyA:
6.41
1c9sI-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 1c9sJ-5dmyA:
undetectable
1c9sK-5dmyA:
undetectable		 1c9sJ-5dmyA:
6.41
1c9sK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.39A 1c9sL-5dmyA:
1.5
1c9sM-5dmyA:
1.2		 1c9sL-5dmyA:
6.41
1c9sM-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 1c9sS-5dmyA:
undetectable
1c9sT-5dmyA:
undetectable		 1c9sS-5dmyA:
6.41
1c9sT-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 GLY A 169
PRO A  86
GLY A  87
GLY A  88
LEU A 597
 None
 0.98A 1ej0A-5dmyA:
undetectable		 1ej0A-5dmyA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.37A 1gtfA-5dmyA:
undetectable
1gtfK-5dmyA:
undetectable		 1gtfA-5dmyA:
6.41
1gtfK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 1gtfA-5dmyA:
undetectable
1gtfB-5dmyA:
undetectable		 1gtfA-5dmyA:
6.41
1gtfB-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 1gtfB-5dmyA:
undetectable
1gtfC-5dmyA:
undetectable		 1gtfB-5dmyA:
6.41
1gtfC-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 1gtfC-5dmyA:
undetectable
1gtfD-5dmyA:
undetectable		 1gtfC-5dmyA:
6.41
1gtfD-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.36A 1gtfE-5dmyA:
undetectable
1gtfF-5dmyA:
1.6		 1gtfE-5dmyA:
6.41
1gtfF-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.36A 1gtfF-5dmyA:
1.6
1gtfG-5dmyA:
undetectable		 1gtfF-5dmyA:
6.41
1gtfG-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 1gtfG-5dmyA:
undetectable
1gtfH-5dmyA:
undetectable		 1gtfG-5dmyA:
6.41
1gtfH-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.36A 1gtfH-5dmyA:
undetectable
1gtfI-5dmyA:
undetectable		 1gtfH-5dmyA:
6.41
1gtfI-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 1gtfI-5dmyA:
undetectable
1gtfJ-5dmyA:
undetectable		 1gtfI-5dmyA:
6.41
1gtfJ-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 7 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 1gtfL-5dmyA:
undetectable
1gtfM-5dmyA:
undetectable		 1gtfL-5dmyA:
6.41
1gtfM-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.39A 1gtfM-5dmyA:
undetectable
1gtfN-5dmyA:
undetectable		 1gtfM-5dmyA:
6.41
1gtfN-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 8 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.39A 1gtfN-5dmyA:
undetectable
1gtfO-5dmyA:
undetectable		 1gtfN-5dmyA:
6.41
1gtfO-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.39A 1gtfO-5dmyA:
undetectable
1gtfP-5dmyA:
undetectable		 1gtfO-5dmyA:
6.41
1gtfP-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.39A 1gtfP-5dmyA:
undetectable
1gtfQ-5dmyA:
undetectable		 1gtfP-5dmyA:
6.41
1gtfQ-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 1gtfT-5dmyA:
undetectable
1gtfU-5dmyA:
undetectable		 1gtfT-5dmyA:
6.41
1gtfU-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 1gtfU-5dmyA:
undetectable
1gtfV-5dmyA:
undetectable		 1gtfU-5dmyA:
6.41
1gtfV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 1gtfL-5dmyA:
undetectable
1gtfV-5dmyA:
undetectable		 1gtfL-5dmyA:
6.41
1gtfV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H1D_A_SAMA301_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 ASN A 159
GLY A 113
TYR A 115
ASN A 362
TYR A 134
 None
 1.45A 1h1dA-5dmyA:
2.4		 1h1dA-5dmyA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 THR A 476
SER A 475
ARG A 477
LEU A 378
 None
 1.11A 1ibgL-5dmyA:
6.1		 1ibgL-5dmyA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 VAL A 668
VAL A 672
ILE A 694
LEU A 649
 None
 0.88A 1iepB-5dmyA:
undetectable		 1iepB-5dmyA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.37A 1utdA-5dmyA:
undetectable
1utdB-5dmyA:
undetectable		 1utdA-5dmyA:
6.41
1utdB-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.39A 1utdC-5dmyA:
undetectable
1utdD-5dmyA:
1.0		 1utdC-5dmyA:
6.41
1utdD-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.39A 1utdD-5dmyA:
1.0
1utdE-5dmyA:
undetectable		 1utdD-5dmyA:
6.41
1utdE-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 1utdG-5dmyA:
undetectable
1utdH-5dmyA:
1.2		 1utdG-5dmyA:
6.41
1utdH-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.42A 1utdA-5dmyA:
undetectable
1utdK-5dmyA:
undetectable		 1utdA-5dmyA:
6.41
1utdK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 1utdN-5dmyA:
undetectable
1utdO-5dmyA:
undetectable		 1utdN-5dmyA:
6.41
1utdO-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 ILE A 848
VAL A 820
ILE A 172
ASP A  63
 None
 0.71A 1uwhA-5dmyA:
undetectable		 1uwhA-5dmyA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 LEU A 819
ILE A 790
ILE A 858
ASP A 812
 None
 0.81A 1uwjA-5dmyA:
undetectable		 1uwjA-5dmyA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_B_CHDB4085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 GLY A 323
THR A 359
THR A 360
PHE A 594
GLY A 593
 None
 1.48A 1v54A-5dmyA:
undetectable
1v54B-5dmyA:
undetectable
1v54T-5dmyA:
undetectable		 1v54A-5dmyA:
19.59
1v54B-5dmyA:
12.15
1v54T-5dmyA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 TYR A 727
ALA A 572
SER A 573
ASN A 563
 None
NA  A 903 ( 4.0A)
None
None
 1.04A 1yvpB-5dmyA:
undetectable		 1yvpB-5dmyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 TRP A 421
TYR A 398
GLY A 414
PHE A 137
 None
 0.99A 2a3cA-5dmyA:
5.6		 2a3cA-5dmyA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 ALA A 773
ALA A 847
ARG A 838
LEU A 819
LEU A 771
 None
 1.14A 2bxqA-5dmyA:
undetectable		 2bxqA-5dmyA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 5 ALA A 145
ILE A 107
ASN A 151
ILE A 153
 None
 1.06A 2h4jA-5dmyA:
undetectable		 2h4jA-5dmyA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 TYR A 167
MET A 116
TYR A 134
HIS A 328
 None
 1.11A 2pncA-5dmyA:
undetectable		 2pncA-5dmyA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 PHE A 459
TRP A 387
GLY A 451
ASN A 484
 None
 1.01A 2qr2A-5dmyA:
undetectable
2qr2B-5dmyA:
undetectable		 2qr2A-5dmyA:
15.27
2qr2B-5dmyA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 ASN A 446
GLU A 447
TYR A 511
GLU A 533
TRP A 591
 None
 0.76A 2v3dB-5dmyA:
14.3		 2v3dB-5dmyA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 PHE A 841
SER A 560
LEU A 558
 None
 0.50A 2w1bA-5dmyA:
undetectable		 2w1bA-5dmyA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 TYR A 511
GLU A 447
ASN A 392
 None
 0.84A 2y7hC-5dmyA:
undetectable		 2y7hC-5dmyA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 804
ASN A 807
GLY A 843
PRO A 803
 None
 1.00A 2ys6A-5dmyA:
undetectable		 2ys6A-5dmyA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 GLY A 323
THR A 359
THR A 360
PHE A 594
GLY A 593
 None
 1.49A 2zxwA-5dmyA:
undetectable
2zxwB-5dmyA:
undetectable
2zxwT-5dmyA:
undetectable		 2zxwA-5dmyA:
19.59
2zxwB-5dmyA:
12.15
2zxwT-5dmyA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 GLY A 323
THR A 359
THR A 360
PHE A 594
GLY A 593
 None
 1.49A 3ablA-5dmyA:
undetectable
3ablB-5dmyA:
undetectable
3ablT-5dmyA:
undetectable		 3ablA-5dmyA:
19.59
3ablB-5dmyA:
12.15
3ablT-5dmyA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 PHE A 594
GLY A 593
GLY A 323
THR A 359
THR A 360
 None
 1.50A 3ag4G-5dmyA:
undetectable
3ag4N-5dmyA:
undetectable
3ag4O-5dmyA:
undetectable		 3ag4G-5dmyA:
7.13
3ag4N-5dmyA:
19.59
3ag4O-5dmyA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 ASP A 626
PHE A 594
SER A 332
 None
 1.00A 3i5uB-5dmyA:
2.3		 3i5uB-5dmyA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 SER A 493
ARG A 165
GLY A 451
GLU A 599
 None
 1.08A 3k9fA-5dmyA:
1.7
3k9fB-5dmyA:
undetectable
3k9fD-5dmyA:
undetectable		 3k9fA-5dmyA:
19.74
3k9fB-5dmyA:
19.74
3k9fD-5dmyA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 GLY A 323
THR A 359
THR A 360
PHE A 594
GLY A 593
 None
 1.49A 3wg7A-5dmyA:
undetectable
3wg7B-5dmyA:
undetectable
3wg7T-5dmyA:
undetectable		 3wg7A-5dmyA:
19.59
3wg7B-5dmyA:
12.15
3wg7T-5dmyA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 ASP A 416
LYS A 417
ASP A 418
 None
 0.79A 4a7tA-5dmyA:
4.3		 4a7tA-5dmyA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 ILE A  70
LEU A 333
GLY A 331
VAL A 336
ALA A 337
 None
 1.23A 4fqsA-5dmyA:
undetectable		 4fqsA-5dmyA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 ILE A  70
LEU A 333
GLY A 331
VAL A 336
ALA A 337
 None
 1.23A 4fqsB-5dmyA:
undetectable		 4fqsB-5dmyA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 LEU A 102
ALA A 145
ILE A 109
VAL A  25
ILE A  98
 None
 0.97A 4hlaB-5dmyA:
undetectable		 4hlaB-5dmyA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 TYR A 530
THR A 480
VAL A 439
ILE A 440
VAL A 379
 None
 1.21A 4jx1B-5dmyA:
undetectable		 4jx1B-5dmyA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 5 ASN A 392
SER A 164
LEU A 161
ASN A 159
 None
 1.11A 4n09C-5dmyA:
undetectable		 4n09C-5dmyA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 ASN A 510
GLY A 482
ASP A 329
ASP A 385
 None
 1.38A 4n49A-5dmyA:
undetectable		 4n49A-5dmyA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 HIS A 830
PRO A 615
LYS A 618
SER A 540
 None
 1.32A 4ndnC-5dmyA:
undetectable		 4ndnC-5dmyA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 HIS A 830
PRO A 615
LYS A 618
SER A 540
 None
 1.31A 4odjA-5dmyA:
undetectable		 4odjA-5dmyA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 SER A 540
TYR A 621
ASP A 555
 None
 0.88A 4rp8C-5dmyA:
undetectable		 4rp8C-5dmyA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 GLY A 514
ASN A 516
SER A 574
THR A 634
ALA A 535
 None
None
None
NA  A 903 (-2.8A)
None
 0.95A 4uckB-5dmyA:
undetectable		 4uckB-5dmyA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 ASP A 595
GLY A 825
ASP A 823
 None
 0.69A 4xdtA-5dmyA:
undetectable		 4xdtA-5dmyA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 GLU A  79
GLU A  81
LEU A 597
GLY A 169
ALA A 335
 NI  A 904 (-2.8A)
NI  A 904 (-3.6A)
None
None
None
 1.14A 4xe5A-5dmyA:
undetectable		 4xe5A-5dmyA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 HIS A 830
PRO A 615
LYS A 618
SER A 540
 None
 1.29A 5a1iA-5dmyA:
undetectable		 5a1iA-5dmyA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 LEU A 349
MET A 352
VAL A 354
ASN A 355
 None
 1.24A 5b8iB-5dmyA:
undetectable		 5b8iB-5dmyA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eeuB-5dmyA:
undetectable
5eeuC-5dmyA:
undetectable		 5eeuB-5dmyA:
6.41
5eeuC-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eeuC-5dmyA:
undetectable
5eeuD-5dmyA:
undetectable		 5eeuC-5dmyA:
6.41
5eeuD-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.41A 5eeuD-5dmyA:
undetectable
5eeuE-5dmyA:
1.5		 5eeuD-5dmyA:
6.41
5eeuE-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5eeuE-5dmyA:
1.5
5eeuF-5dmyA:
1.6		 5eeuE-5dmyA:
6.41
5eeuF-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5eeuG-5dmyA:
undetectable
5eeuH-5dmyA:
1.6		 5eeuG-5dmyA:
6.41
5eeuH-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5eeuH-5dmyA:
1.6
5eeuI-5dmyA:
1.6		 5eeuH-5dmyA:
6.41
5eeuI-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.35A 5eeuJ-5dmyA:
1.4
5eeuK-5dmyA:
1.6		 5eeuJ-5dmyA:
6.41
5eeuK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eeuA-5dmyA:
1.5
5eeuK-5dmyA:
1.6		 5eeuA-5dmyA:
6.41
5eeuK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5eeuL-5dmyA:
1.6
5eeuV-5dmyA:
1.5		 5eeuL-5dmyA:
6.41
5eeuV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5eeuL-5dmyA:
1.6
5eeuM-5dmyA:
1.5		 5eeuL-5dmyA:
6.41
5eeuM-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.37A 5eeuN-5dmyA:
undetectable
5eeuO-5dmyA:
1.6		 5eeuN-5dmyA:
6.41
5eeuO-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eeuU-5dmyA:
1.5
5eeuV-5dmyA:
1.5		 5eeuU-5dmyA:
6.41
5eeuV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eevB-5dmyA:
undetectable
5eevC-5dmyA:
undetectable		 5eevB-5dmyA:
6.41
5eevC-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eevC-5dmyA:
undetectable
5eevD-5dmyA:
undetectable		 5eevC-5dmyA:
6.41
5eevD-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.41A 5eevD-5dmyA:
undetectable
5eevE-5dmyA:
1.6		 5eevD-5dmyA:
6.41
5eevE-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5eevE-5dmyA:
1.6
5eevF-5dmyA:
1.6		 5eevE-5dmyA:
6.41
5eevF-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5eevG-5dmyA:
undetectable
5eevH-5dmyA:
undetectable		 5eevG-5dmyA:
6.41
5eevH-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5eevH-5dmyA:
undetectable
5eevI-5dmyA:
1.5		 5eevH-5dmyA:
6.41
5eevI-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.35A 5eevJ-5dmyA:
undetectable
5eevK-5dmyA:
1.6		 5eevJ-5dmyA:
6.41
5eevK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eevA-5dmyA:
1.5
5eevK-5dmyA:
1.6		 5eevA-5dmyA:
6.41
5eevK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5eevL-5dmyA:
1.6
5eevM-5dmyA:
1.5		 5eevL-5dmyA:
6.41
5eevM-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.37A 5eevN-5dmyA:
1.5
5eevO-5dmyA:
1.6		 5eevN-5dmyA:
6.41
5eevO-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eevU-5dmyA:
1.6
5eevV-5dmyA:
1.5		 5eevU-5dmyA:
6.41
5eevV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eewB-5dmyA:
undetectable
5eewC-5dmyA:
undetectable		 5eewB-5dmyA:
6.41
5eewC-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eewC-5dmyA:
undetectable
5eewD-5dmyA:
undetectable		 5eewC-5dmyA:
6.41
5eewD-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5eewD-5dmyA:
undetectable
5eewE-5dmyA:
1.6		 5eewD-5dmyA:
6.41
5eewE-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5eewE-5dmyA:
1.6
5eewF-5dmyA:
1.6		 5eewE-5dmyA:
6.41
5eewF-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5eewG-5dmyA:
undetectable
5eewH-5dmyA:
undetectable		 5eewG-5dmyA:
6.41
5eewH-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5eewH-5dmyA:
undetectable
5eewI-5dmyA:
1.5		 5eewH-5dmyA:
6.41
5eewI-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.35A 5eewJ-5dmyA:
undetectable
5eewK-5dmyA:
1.6		 5eewJ-5dmyA:
6.41
5eewK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eewA-5dmyA:
1.5
5eewK-5dmyA:
1.6		 5eewA-5dmyA:
6.41
5eewK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5eewL-5dmyA:
1.6
5eewM-5dmyA:
1.5		 5eewL-5dmyA:
6.41
5eewM-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5eewN-5dmyA:
undetectable
5eewO-5dmyA:
1.6		 5eewN-5dmyA:
6.41
5eewO-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eewU-5dmyA:
1.6
5eewV-5dmyA:
1.5		 5eewU-5dmyA:
6.41
5eewV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eexB-5dmyA:
undetectable
5eexC-5dmyA:
undetectable		 5eexB-5dmyA:
6.41
5eexC-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eexC-5dmyA:
undetectable
5eexD-5dmyA:
undetectable		 5eexC-5dmyA:
6.41
5eexD-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5eexD-5dmyA:
undetectable
5eexE-5dmyA:
1.6		 5eexD-5dmyA:
6.41
5eexE-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5eexE-5dmyA:
1.6
5eexF-5dmyA:
1.6		 5eexE-5dmyA:
6.41
5eexF-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5eexG-5dmyA:
undetectable
5eexH-5dmyA:
undetectable		 5eexG-5dmyA:
6.41
5eexH-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5eexH-5dmyA:
undetectable
5eexI-5dmyA:
undetectable		 5eexH-5dmyA:
6.41
5eexI-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.35A 5eexJ-5dmyA:
undetectable
5eexK-5dmyA:
1.6		 5eexJ-5dmyA:
6.41
5eexK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eexA-5dmyA:
1.5
5eexK-5dmyA:
1.6		 5eexA-5dmyA:
6.41
5eexK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.41A 5eexL-5dmyA:
1.5
5eexV-5dmyA:
1.6		 5eexL-5dmyA:
6.41
5eexV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5eexL-5dmyA:
1.5
5eexM-5dmyA:
1.6		 5eexL-5dmyA:
6.41
5eexM-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5eexN-5dmyA:
undetectable
5eexO-5dmyA:
1.5		 5eexN-5dmyA:
6.41
5eexO-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eexQ-5dmyA:
1.4
5eexR-5dmyA:
1.5		 5eexQ-5dmyA:
6.41
5eexR-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eexU-5dmyA:
1.6
5eexV-5dmyA:
1.6		 5eexU-5dmyA:
6.41
5eexV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eeyB-5dmyA:
1.5
5eeyC-5dmyA:
undetectable		 5eeyB-5dmyA:
6.41
5eeyC-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eeyC-5dmyA:
undetectable
5eeyD-5dmyA:
undetectable		 5eeyC-5dmyA:
6.41
5eeyD-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5eeyD-5dmyA:
undetectable
5eeyE-5dmyA:
1.5		 5eeyD-5dmyA:
6.41
5eeyE-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5eeyE-5dmyA:
1.5
5eeyF-5dmyA:
1.6		 5eeyE-5dmyA:
6.41
5eeyF-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5eeyG-5dmyA:
undetectable
5eeyH-5dmyA:
undetectable		 5eeyG-5dmyA:
6.41
5eeyH-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5eeyH-5dmyA:
undetectable
5eeyI-5dmyA:
undetectable		 5eeyH-5dmyA:
6.41
5eeyI-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.34A 5eeyJ-5dmyA:
1.4
5eeyK-5dmyA:
1.6		 5eeyJ-5dmyA:
6.41
5eeyK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eeyA-5dmyA:
undetectable
5eeyK-5dmyA:
1.6		 5eeyA-5dmyA:
6.41
5eeyK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.41A 5eeyL-5dmyA:
1.4
5eeyV-5dmyA:
1.6		 5eeyL-5dmyA:
6.41
5eeyV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5eeyL-5dmyA:
1.4
5eeyM-5dmyA:
1.5		 5eeyL-5dmyA:
6.41
5eeyM-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5eeyN-5dmyA:
undetectable
5eeyO-5dmyA:
1.5		 5eeyN-5dmyA:
6.41
5eeyO-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eeyQ-5dmyA:
1.5
5eeyR-5dmyA:
1.5		 5eeyQ-5dmyA:
6.41
5eeyR-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eeyU-5dmyA:
1.5
5eeyV-5dmyA:
1.6		 5eeyU-5dmyA:
6.41
5eeyV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eezB-5dmyA:
1.7
5eezC-5dmyA:
undetectable		 5eezB-5dmyA:
6.41
5eezC-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eezC-5dmyA:
undetectable
5eezD-5dmyA:
undetectable		 5eezC-5dmyA:
6.41
5eezD-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5eezD-5dmyA:
undetectable
5eezE-5dmyA:
undetectable		 5eezD-5dmyA:
6.41
5eezE-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5eezE-5dmyA:
undetectable
5eezF-5dmyA:
1.6		 5eezE-5dmyA:
6.41
5eezF-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5eezG-5dmyA:
undetectable
5eezH-5dmyA:
undetectable		 5eezG-5dmyA:
6.41
5eezH-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5eezH-5dmyA:
undetectable
5eezI-5dmyA:
undetectable		 5eezH-5dmyA:
6.41
5eezI-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.34A 5eezJ-5dmyA:
1.4
5eezK-5dmyA:
1.6		 5eezJ-5dmyA:
6.41
5eezK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eezA-5dmyA:
1.6
5eezK-5dmyA:
1.6		 5eezA-5dmyA:
6.41
5eezK-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 8 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.41A 5eezL-5dmyA:
1.6
5eezV-5dmyA:
1.6		 5eezL-5dmyA:
6.41
5eezV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5eezL-5dmyA:
1.6
5eezM-5dmyA:
1.6		 5eezL-5dmyA:
6.41
5eezM-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5eezN-5dmyA:
1.6
5eezO-5dmyA:
1.4		 5eezN-5dmyA:
6.41
5eezO-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eezQ-5dmyA:
1.5
5eezR-5dmyA:
1.5		 5eezQ-5dmyA:
6.41
5eezR-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5eezU-5dmyA:
1.6
5eezV-5dmyA:
1.6		 5eezU-5dmyA:
6.41
5eezV-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5ef0B-5dmyA:
undetectable
5ef0C-5dmyA:
undetectable		 5ef0B-5dmyA:
6.41
5ef0C-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5ef0C-5dmyA:
undetectable
5ef0D-5dmyA:
undetectable		 5ef0C-5dmyA:
6.41
5ef0D-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5ef0D-5dmyA:
undetectable
5ef0E-5dmyA:
undetectable		 5ef0D-5dmyA:
6.41
5ef0E-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5ef0E-5dmyA:
undetectable
5ef0F-5dmyA:
1.6		 5ef0E-5dmyA:
6.41
5ef0F-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5ef0G-5dmyA:
undetectable
5ef0H-5dmyA:
undetectable		 5ef0G-5dmyA:
6.41
5ef0H-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5ef0H-5dmyA:
undetectable
5ef0I-5dmyA:
undetectable		 5ef0H-5dmyA:
6.41
5ef0I-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.34A 5ef0J-5dmyA:
1.4
5ef0K-5dmyA:
1.6		 5ef0J-5dmyA:
6.41
5ef0K-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef0A-5dmyA:
1.5
5ef0K-5dmyA:
1.6		 5ef0A-5dmyA:
6.41
5ef0K-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.41A 5ef0L-5dmyA:
1.5
5ef0V-5dmyA:
1.5		 5ef0L-5dmyA:
6.41
5ef0V-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5ef0L-5dmyA:
1.5
5ef0M-5dmyA:
1.6		 5ef0L-5dmyA:
6.41
5ef0M-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5ef0N-5dmyA:
1.6
5ef0O-5dmyA:
1.5		 5ef0N-5dmyA:
6.41
5ef0O-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef0Q-5dmyA:
1.5
5ef0R-5dmyA:
1.5		 5ef0Q-5dmyA:
6.41
5ef0R-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef0U-5dmyA:
1.6
5ef0V-5dmyA:
1.5		 5ef0U-5dmyA:
6.41
5ef0V-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5ef1B-5dmyA:
undetectable
5ef1C-5dmyA:
undetectable		 5ef1B-5dmyA:
6.41
5ef1C-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5ef1C-5dmyA:
undetectable
5ef1D-5dmyA:
undetectable		 5ef1C-5dmyA:
6.41
5ef1D-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5ef1D-5dmyA:
undetectable
5ef1E-5dmyA:
undetectable		 5ef1D-5dmyA:
6.41
5ef1E-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5ef1E-5dmyA:
undetectable
5ef1F-5dmyA:
1.6		 5ef1E-5dmyA:
6.41
5ef1F-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5ef1G-5dmyA:
undetectable
5ef1H-5dmyA:
undetectable		 5ef1G-5dmyA:
6.41
5ef1H-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5ef1H-5dmyA:
undetectable
5ef1I-5dmyA:
undetectable		 5ef1H-5dmyA:
6.41
5ef1I-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.34A 5ef1J-5dmyA:
1.4
5ef1K-5dmyA:
1.6		 5ef1J-5dmyA:
6.41
5ef1K-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef1A-5dmyA:
1.5
5ef1K-5dmyA:
1.6		 5ef1A-5dmyA:
6.41
5ef1K-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 8 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.41A 5ef1L-5dmyA:
1.5
5ef1V-5dmyA:
1.5		 5ef1L-5dmyA:
6.41
5ef1V-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5ef1L-5dmyA:
1.4
5ef1M-5dmyA:
1.6		 5ef1L-5dmyA:
6.41
5ef1M-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5ef1N-5dmyA:
1.5
5ef1O-5dmyA:
1.5		 5ef1N-5dmyA:
6.41
5ef1O-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef1Q-5dmyA:
1.5
5ef1R-5dmyA:
1.4		 5ef1Q-5dmyA:
6.41
5ef1R-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef1U-5dmyA:
1.6
5ef1V-5dmyA:
1.5		 5ef1U-5dmyA:
6.41
5ef1V-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5ef2B-5dmyA:
undetectable
5ef2C-5dmyA:
undetectable		 5ef2B-5dmyA:
6.41
5ef2C-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5ef2C-5dmyA:
undetectable
5ef2D-5dmyA:
undetectable		 5ef2C-5dmyA:
6.41
5ef2D-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5ef2D-5dmyA:
undetectable
5ef2E-5dmyA:
undetectable		 5ef2D-5dmyA:
6.41
5ef2E-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.39A 5ef2E-5dmyA:
undetectable
5ef2F-5dmyA:
1.6		 5ef2E-5dmyA:
6.41
5ef2F-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5ef2G-5dmyA:
undetectable
5ef2H-5dmyA:
undetectable		 5ef2G-5dmyA:
6.41
5ef2H-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5ef2H-5dmyA:
undetectable
5ef2I-5dmyA:
undetectable		 5ef2H-5dmyA:
6.41
5ef2I-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.34A 5ef2J-5dmyA:
1.4
5ef2K-5dmyA:
1.6		 5ef2J-5dmyA:
6.41
5ef2K-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef2A-5dmyA:
1.5
5ef2K-5dmyA:
1.6		 5ef2A-5dmyA:
6.41
5ef2K-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 8 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.41A 5ef2L-5dmyA:
1.4
5ef2V-5dmyA:
1.6		 5ef2L-5dmyA:
6.41
5ef2V-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5ef2L-5dmyA:
1.6
5ef2M-5dmyA:
1.5		 5ef2L-5dmyA:
6.41
5ef2M-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5ef2N-5dmyA:
undetectable
5ef2O-5dmyA:
1.5		 5ef2N-5dmyA:
6.41
5ef2O-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef2Q-5dmyA:
1.4
5ef2R-5dmyA:
1.5		 5ef2Q-5dmyA:
6.41
5ef2R-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef2U-5dmyA:
1.6
5ef2V-5dmyA:
1.6		 5ef2U-5dmyA:
6.41
5ef2V-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5ef3B-5dmyA:
undetectable
5ef3C-5dmyA:
undetectable		 5ef3B-5dmyA:
6.41
5ef3C-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5ef3C-5dmyA:
undetectable
5ef3D-5dmyA:
undetectable		 5ef3C-5dmyA:
6.41
5ef3D-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.40A 5ef3D-5dmyA:
undetectable
5ef3E-5dmyA:
undetectable		 5ef3D-5dmyA:
6.41
5ef3E-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.38A 5ef3E-5dmyA:
undetectable
5ef3F-5dmyA:
1.6		 5ef3E-5dmyA:
6.41
5ef3F-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5ef3G-5dmyA:
undetectable
5ef3H-5dmyA:
undetectable		 5ef3G-5dmyA:
6.41
5ef3H-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.37A 5ef3H-5dmyA:
undetectable
5ef3I-5dmyA:
undetectable		 5ef3H-5dmyA:
6.41
5ef3I-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 674
GLY A 758
ALA A 741
HIS A 647
THR A 756
 None
 1.34A 5ef3J-5dmyA:
1.4
5ef3K-5dmyA:
1.6		 5ef3J-5dmyA:
6.41
5ef3K-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef3A-5dmyA:
1.5
5ef3K-5dmyA:
1.6		 5ef3A-5dmyA:
6.41
5ef3K-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5ef3L-5dmyA:
1.6
5ef3M-5dmyA:
1.4		 5ef3L-5dmyA:
6.41
5ef3M-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.38A 5ef3N-5dmyA:
undetectable
5ef3O-5dmyA:
1.5		 5ef3N-5dmyA:
6.41
5ef3O-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef3Q-5dmyA:
1.4
5ef3R-5dmyA:
1.5		 5ef3Q-5dmyA:
6.41
5ef3R-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 GLY A 758
ALA A 741
HIS A 647
THR A 756
THR A 674
 None
 1.40A 5ef3U-5dmyA:
1.6
5ef3V-5dmyA:
1.6		 5ef3U-5dmyA:
6.41
5ef3V-5dmyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 ASN A 159
GLY A 113
TYR A 115
ASN A 362
TYR A 134
 None
 1.50A 5fhrB-5dmyA:
2.0		 5fhrB-5dmyA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 ILE A 538
VAL A 571
ALA A 575
GLY A 531
THR A 509
 None
 1.14A 5igiA-5dmyA:
undetectable		 5igiA-5dmyA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 MET A 208
ILE A 193
ALA A 239
ALA A 240
GLY A 235
 None
 1.32A 5igpA-5dmyA:
undetectable		 5igpA-5dmyA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 VAL A 659
VAL A 660
THR A 764
THR A 765
TRP A 734
 None
 1.37A 5jn8A-5dmyA:
undetectable		 5jn8A-5dmyA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 VAL A 659
VAL A 660
THR A 764
THR A 765
TRP A 734
 None
 1.37A 5jn9B-5dmyA:
undetectable		 5jn9B-5dmyA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 VAL A 659
VAL A 660
THR A 764
THR A 765
TRP A 734
 None
 1.36A 5jn9D-5dmyA:
undetectable		 5jn9D-5dmyA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 VAL A 659
VAL A 660
THR A 764
THR A 765
TRP A 734
 None
 1.38A 5jncB-5dmyA:
undetectable		 5jncB-5dmyA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 VAL A 659
VAL A 660
THR A 764
THR A 765
TRP A 734
 None
 1.37A 5ku6A-5dmyA:
undetectable		 5ku6A-5dmyA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 THR A 429
PRO A 136
ASP A 112
 None
 0.66A 5l8dB-5dmyA:
undetectable		 5l8dB-5dmyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 THR A 429
PRO A 136
ASP A 112
 None
 0.66A 5mwuB-5dmyA:
undetectable		 5mwuB-5dmyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 TYR A  84
SER A 608
TRP A 614
 None
 0.93A 5n8jB-5dmyA:
undetectable		 5n8jB-5dmyA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 TYR A  84
SER A  77
TRP A 614
 None
 1.04A 5n8jA-5dmyA:
undetectable		 5n8jA-5dmyA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 TYR A  84
SER A 608
TRP A 614
 None
 0.94A 5n8jA-5dmyA:
undetectable		 5n8jA-5dmyA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 TYR A  84
SER A  77
TRP A 614
 None
 1.02A 5n8jD-5dmyA:
undetectable		 5n8jD-5dmyA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 TYR A  84
SER A 608
TRP A 614
 None
 1.01A 5n8jD-5dmyA:
undetectable		 5n8jD-5dmyA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 LEU A 368
ALA A 365
ASP A 112
VAL A 379
ILE A 357
 None
 1.16A 5om2A-5dmyA:
undetectable
5om2B-5dmyA:
undetectable		 5om2A-5dmyA:
6.80
5om2B-5dmyA:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA304_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 ARG A 282
THR A 237
GLY A 235
PHE A 231
 None
 1.30A 5uunA-5dmyA:
undetectable		 5uunA-5dmyA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 THR A 359
MET A 326
HIS A 327
 None
 0.80A 5uunA-5dmyA:
undetectable		 5uunA-5dmyA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 VAL A 507
HIS A 524
SER A 512
THR A 509
 None
 1.03A 5vkqA-5dmyA:
undetectable
5vkqD-5dmyA:
undetectable		 5vkqA-5dmyA:
19.73
5vkqD-5dmyA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 PHE A 594
GLY A 593
GLY A 323
THR A 359
THR A 360
 None
 1.48A 5xdqG-5dmyA:
undetectable
5xdqN-5dmyA:
undetectable
5xdqO-5dmyA:
undetectable		 5xdqG-5dmyA:
7.13
5xdqN-5dmyA:
19.59
5xdqO-5dmyA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 GLY A 323
THR A 359
THR A 360
PHE A 594
GLY A 593
 None
 1.48A 5xdxA-5dmyA:
undetectable
5xdxB-5dmyA:
undetectable
5xdxT-5dmyA:
undetectable		 5xdxA-5dmyA:
19.59
5xdxB-5dmyA:
12.15
5xdxT-5dmyA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_O_CHDO301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 PHE A 594
GLY A 593
GLY A 323
THR A 359
THR A 360
 None
 1.49A 5xdxG-5dmyA:
undetectable
5xdxN-5dmyA:
undetectable
5xdxO-5dmyA:
undetectable		 5xdxG-5dmyA:
7.13
5xdxN-5dmyA:
19.59
5xdxO-5dmyA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 TYR A  68
HIS A  66
PHE A  41
 None
 1.00A 6esmA-5dmyA:
undetectable		 6esmA-5dmyA:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 GLN A  72
THR A  71
HIS A 328
ASN A 159
GLY A  87
 None
 1.37A 6exiD-5dmyA:
2.4		 6exiD-5dmyA:
6.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 HIS A 830
PRO A 615
LYS A 618
SER A 540
 None
 1.29A 6g6rA-5dmyA:
undetectable		 6g6rA-5dmyA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A  67
SER A  69
SER A 390
ASN A 159
 None
 1.09A 6giqL-5dmyA:
undetectable
6giqP-5dmyA:
undetectable
6giqT-5dmyA:
undetectable		 6giqL-5dmyA:
22.00
6giqP-5dmyA:
12.92
6giqT-5dmyA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 397
ARG A 165
GLU A  81
GLU A 450
 None
None
NI  A 904 (-3.6A)
None
 1.15A 6mn4B-5dmyA:
undetectable		 6mn4B-5dmyA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 397
ARG A 165
GLU A  81
GLU A 450
 None
None
NI  A 904 (-3.6A)
None
 1.01A 6mn4C-5dmyA:
undetectable		 6mn4C-5dmyA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 TRP A 591
HIS A 361
THR A 360
GLU A 447
 None
 0.99A 6mn4E-5dmyA:
undetectable		 6mn4E-5dmyA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 5dmy BETA-GALACTOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 ALA A 335
GLY A 334
LEU A 597
GLY A  87
ARG A 174
 None
 1.28A 6nm4B-5dmyA:
undetectable		 6nm4B-5dmyA:
12.27