SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5dn2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5dn2 NEUROPILIN-2
(Homo
sapiens) 		3 / 3 GLY A 426
THR A 340
ASN A 278
 None
 0.73A 3v4tD-5dn2A:
undetectable		 3v4tD-5dn2A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5dn2 NEUROPILIN-2
(Homo
sapiens) 		4 / 8 GLY A 346
THR A 305
TRP A 318
TYR A 299
 None
 0.87A 5flcB-5dn2A:
undetectable		 5flcB-5dn2A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5dn2 NEUROPILIN-2
(Homo
sapiens) 		4 / 8 GLY A 346
THR A 305
TRP A 318
TYR A 299
 None
 0.86A 5flcF-5dn2A:
undetectable		 5flcF-5dn2A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_0
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 5dn2 NEUROPILIN-2
(Homo
sapiens) 		5 / 12 MET A 338
THR A 367
THR A 404
VAL A 365
TYR A 375
 None
 1.47A 6ak3A-5dn2A:
undetectable		 6ak3A-5dn2A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 5dn2 NEUROPILIN-2
(Homo
sapiens) 		5 / 9 ALA A 390
ALA A 419
GLY A 346
GLY A 317
SER A 349
 None
 1.15A 6bklE-5dn2A:
undetectable
6bklF-5dn2A:
undetectable
6bklG-5dn2A:
undetectable
6bklH-5dn2A:
undetectable		 6bklE-5dn2A:
11.33
6bklF-5dn2A:
11.33
6bklG-5dn2A:
11.33
6bklH-5dn2A:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5dn2 NEUROPILIN-2
(Homo
sapiens) 		5 / 10 VAL A 407
LEU A 339
LEU A 398
LEU A 422
LEU A 424
 None
 0.84A 6f5uA-5dn2A:
undetectable
6f5uB-5dn2A:
undetectable		 6f5uA-5dn2A:
22.76
6f5uB-5dn2A:
21.23